(Q41251781)

28 September 2017

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title

What's new in ras genes? Physiological role of ras genes in signal transduction and significance of ras gene activation in tumorigenesis (English)

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28 September 2017

Waldmann V

1

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28 September 2017

Rabes HM

series ordinal

2

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28 September 2017

publication date

1 September 1996

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Pathology, Research and Practice

28 September 2017

published in

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28 September 2017

volume

192

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28 September 2017

issue

9

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28 September 2017

page(s)

883-891

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Complex formation between RAS and RAF and other protein kinases

28 September 2017

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A novel mechanism of Ha-ras oncogene action: regulation of fibronectin mRNA levels by a nuclear posttranscriptional event

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Critical binding and regulatory interactions between Ras and Raf occur through a small, stable N-terminal domain of Raf and specific Ras effector residues

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RapV12 antagonizes Ras-dependent activation of ERK1 and ERK2 by LPA and EGF in Rat-1 fibroblasts

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What's new in breast cancer? Molecular perspectives of cancer development and the role of the oncogene c-erbB-2 in prognosis and disease

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Identification of the SH3 domain of GAP as an essential sequence for Ras-GAP-mediated signaling

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7 January 2021

Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation

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7 January 2021

The pathway to signal achievement

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7 January 2021

A single amino acid change in Raf-1 inhibits Ras binding and alters Raf-1 function

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7 January 2021

K-ras gene mutation as a pathogenetic and diagnostic marker in human cancer

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7 January 2021

A genetic model for colorectal tumorigenesis

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7 January 2021

Guanine-nucleotide exchange factors: a family of positive regulators of Ras and related GTPases

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Bcl-2 associates with the ras-related protein R-ras p23

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7 January 2021

Detection of high incidence of K-ras oncogenes during human colon tumorigenesis

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Non-involvement of ras mutations in flat colorectal adenomas and carcinomas

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7 January 2021

Mitogen-activated protein kinase activation resulting from selective oncogene expression in NIH 3T3 and rat 1a cells

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7 January 2021

Farnesyltransferase inhibitors: Ras research yields a potential cancer therapeutic

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7 January 2021

Prenyl proteins in eukaryotic cells: a new type of membrane anchor

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7 January 2021

Pseudopeptide inhibitors of Ras farnesyl-protein transferase

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7 January 2021

Immunodetection of the p21-ras products in human normal and preneoplastic tissues and solid tumors: a review

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7 January 2021

Activation of the MAP kinase pathway by the protein kinase raf

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7 January 2021

Mutations in the K-ras oncogene induced by 1,2-dimethylhydrazine in preneoplastic and neoplastic rat colonic mucosa

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PDGF beta-receptor stimulates tyrosine phosphorylation of GAP and association of GAP with a signaling complex

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Structure and function of signal-transducing GTP-binding proteins

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7 January 2021

The Ras signal transduction pathway

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Point mutation of c-Ki-ras oncogene in gastric adenoma and adenocarcinoma with tubular differentiation.

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7 January 2021

Raf-1 activates MAP kinase-kinase

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7 January 2021

Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane

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7 January 2021

Growth factors induce nuclear translocation of MAP kinases (p42mapk and p44mapk) but not of their activator MAP kinase kinase (p45mapkk) in fibroblasts

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7 January 2021

Nerve growth factor stimulation of the Ras-guanine nucleotide exchange factor and GAP activities

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7 January 2021

Characterization of downstream elements in a Raf-1 pathway

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7 January 2021

cPLA2 is phosphorylated and activated by MAP kinase

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7 January 2021

Function and regulation of ras.

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7 January 2021

Posttranslational modification of proteins by isoprenoids in mammalian cells

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7 January 2021

MAP kinase kinase kinase, MAP kinase kinase and MAP kinase

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7 January 2021

CRK protein binds to two guanine nucleotide-releasing proteins for the Ras family and modulates nerve growth factor-induced activation of Ras in PC12 cells

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7 January 2021

Activators and effectors of ras p21 proteins

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7 January 2021

GTPase-activating protein SH2-SH3 domains induce gene expression in a Ras-dependent fashion

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7 January 2021

Ras activation by insulin and epidermal growth factor through enhanced exchange of guanine nucleotides on p21ras

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7 January 2021

PDGF induction of tyrosine phosphorylation of GTPase activating protein

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7 January 2021

Complexes of Ras.GTP with Raf-1 and mitogen-activated protein kinase kinase

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7 January 2021

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7 January 2021

Lysis of ras oncogene-transformed cells by specific cytotoxic T lymphocytes elicited by primary in vitro immunization with mutated ras peptide

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7 January 2021

Mitogen-activated protein kinases: versatile transducers for cell signaling

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7 January 2021

A novel transforming protein (SHC) with an SH2 domain is implicated in mitogenic signal transduction

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7 January 2021

APC mutations occur early during colorectal tumorigenesis

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7 January 2021

Ras regulatory interactions: novel targets for anti-cancer intervention?

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7 January 2021

Farnesyltransferase inhibition causes morphological reversion of ras-transformed cells by a complex mechanism that involves regulation of the actin cytoskeleton

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7 January 2021

Vesicle-mediated protein sorting

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7 January 2021

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7 January 2021

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

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7 January 2021

The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

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7 January 2021

Mutations in the ras protooncogenes are rare events in renal cell cancer

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7 January 2021

The ras oncogenes in human lung cancer

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7 January 2021

How receptor tyrosine kinases activate Ras.

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7 January 2021

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7 January 2021

Induction of mammary carcinomas in rats by nitroso-methylurea involves malignant activation of H-ras-1 locus by single point mutations.

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7 January 2021

Independent molecular pathways in initiation and loss of hormone responsiveness of breast carcinomas.

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7 January 2021

Inhibitors of Ras farnesyltransferases

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7 January 2021

Coupling between p210bcr-abl and Shc and Grb2 adaptor proteins in hematopoietic cells permits growth factor receptor-independent link to ras activation pathway

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7 January 2021

Detection of K-ras mutation in colonic effluent samples from patients without evidence of colorectal carcinoma

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7 January 2021

Sustained activation of the mitogen-activated protein (MAP) kinase cascade may be required for differentiation of PC12 cells. Comparison of the effects of nerve growth factor and epidermal growth factor

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7 January 2021

The ras protein family: evolutionary tree and role of conserved amino acids

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7 January 2021

Mammalian Ras interacts directly with the serine/threonine kinase Raf

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7 January 2021

Cell proliferation and prevalence of ras gene mutations in 7,12-dimethylbenz(a)anthracene (DMBA)-induced rat mammary tumors.

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7 January 2021

Signal transduction pathways involving the Raf proto-oncogene

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7 January 2021

Inhibition of the EGF-activated MAP kinase signaling pathway by adenosine 3',5'-monophosphate

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7 January 2021

Direct mutagenesis of Ha-ras-1 oncogenes by N-nitroso-N-methylurea during initiation of mammary carcinogenesis in rats.

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7 January 2021

Normal and oncogenic p21ras proteins bind to the amino-terminal regulatory domain of c-Raf-1

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7 January 2021

10.1016/S0344-0338(96)80067-7

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