(Q41435961)

30 September 2017

Gpr124 is essential for blood-brain barrier integrity in central nervous system disease (English)

1 reference

Adhesion G protein-coupled receptor A2

30 September 2017

1 reference

1 reference

GOA release 2020-03-11

author

Haijing Zhang

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28288111%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Rona Giffard

31

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28288111%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

29

Michael Snyder

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28288111%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

author name string

Junlei Chang

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28288111%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Michael R Mancuso

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28288111%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Carolina Maier

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28288111%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Xibin Liang

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28288111%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Kanako Yuki

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28288111%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Lu Yang

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28288111%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Jeffrey W Kwong

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28288111%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Jing Wang

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28288111%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Varsha Rao

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28288111%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Mario Vallon

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28288111%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Cynthia Kosinski

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28288111%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Amanda T Mah

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28288111%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Lijun Xu

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28288111%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Le Li

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28288111%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Sharareh Gholamin

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28288111%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Teresa F Reyes

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28288111%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Rui Li

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28288111%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Frank Kuhnert

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28288111%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Xiaoyuan Han

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28288111%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Jenny Yuan

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28288111%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Ari D Brettman

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28288111%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Lauren Daly

24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28288111%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

David C Corney

25

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28288111%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Samuel H Cheshier

26

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28288111%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Linda D Shortliffe

27

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28288111%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Xiwei Wu

28

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28288111%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Pak Chan

30

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28288111%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Howard Y Chang

32

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28288111%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Katrin Andreasson

33

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28288111%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Calvin J Kuo

34

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28288111%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Shin-Heng Chiou

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28288111%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

language of work or name

English

0 references

publication date

13 March 2017

1 reference

30 September 2017

11

1 reference

inferred from page(s)

published in

Nature Medicine

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28288111%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

volume

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28288111%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28288111%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

page(s)

450-460

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28288111%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

31 May 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5559385/fullTextXML

inferred from PubMed Central ID database lookup

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1 October 2017

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Wnt/β-catenin coupled with HIF-1α/VEGF signaling pathways involved in galangin neurovascular unit protection from focal cerebral ischemia

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Gpr124 controls CNS angiogenesis and blood-brain barrier integrity by promoting ligand-specific canonical wnt signaling

1 October 2017

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1 October 2017

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1 October 2017

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Canonical WNT signaling components in vascular development and barrier formation

1 October 2017

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Mfsd2a is critical for the formation and function of the blood-brain barrier

1 October 2017

1 reference

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Developmental and pathological angiogenesis in the central nervous system

1 October 2017

1 reference

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Capillary pericytes regulate cerebral blood flow in health and disease

1 October 2017

1 reference

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Novel insights into the development and maintenance of the blood-brain barrier

1 October 2017

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Development, maintenance and disruption of the blood-brain barrier

1 October 2017

1 reference

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Wnt activation of immortalized brain endothelial cells as a tool for generating a standardized model of the blood brain barrier in vitro

1 October 2017

1 reference

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Ablation of astrocytic laminin impairs vascular smooth muscle cell function and leads to hemorrhagic stroke.

1 October 2017

1 reference

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Norrin/Frizzled4 signaling in retinal vascular development and blood brain barrier plasticity

1 October 2017

1 reference

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Endothelial Wnt/β-catenin signaling inhibits glioma angiogenesis and normalizes tumor blood vessels by inducing PDGF-B expression

1 October 2017

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Derivation of blood-brain barrier endothelial cells from human pluripotent stem cells

1 October 2017

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Sex, stroke, and inflammation: the potential for estrogen-mediated immunoprotection in stroke

1 October 2017

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Central nervous system pericytes in health and disease

1 October 2017

1 reference

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PDGFR-β as a positive regulator of tissue repair in a mouse model of focal cerebral ischemia

1 October 2017

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Pericytes: developmental, physiological, and pathological perspectives, problems, and promises

1 October 2017

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Principles and mechanisms of vessel normalization for cancer and other angiogenic diseases

1 October 2017

1 reference

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GPR124, an orphan G protein-coupled receptor, is required for CNS-specific vascularization and establishment of the blood-brain barrier

1 October 2017

1 reference

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Angiogenic sprouting into neural tissue requires Gpr124, an orphan G protein-coupled receptor.

1 October 2017

1 reference

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Essential regulation of CNS angiogenesis by the orphan G protein-coupled receptor GPR124.

1 October 2017

1 reference

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The Mouse Blood-Brain Barrier Transcriptome: A New Resource for Understanding the Development and Function of Brain Endothelial Cells

1 October 2017

1 reference

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Expression of the Norrie disease gene (Ndp) in developing and adult mouse eye, ear, and brain

1 October 2017

1 reference

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Pericytes Control Key Neurovascular Functions and Neuronal Phenotype in the Adult Brain and during Brain Aging

1 October 2017

1 reference

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Pericytes regulate the blood-brain barrier

1 October 2017

1 reference

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Pericytes are required for blood-brain barrier integrity during embryogenesis

1 October 2017

1 reference

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Involvement of the Reck tumor suppressor protein in maternal and embryonic vascular remodeling in mice

1 October 2017

1 reference

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Ephrin-B2 controls VEGF-induced angiogenesis and lymphangiogenesis

1 October 2017

1 reference

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3'-end sequencing for expression quantification (3SEQ) from archival tumor samples

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5559385

TSPAN12 regulates retinal vascular development by promoting Norrin- but not Wnt-induced FZD4/beta-catenin signaling

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5559385

Norrin, frizzled-4, and Lrp5 signaling in endothelial cells controls a genetic program for retinal vascularization

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5559385

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5559385

Wnt/beta-catenin signaling is required for CNS, but not non-CNS, angiogenesis

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5559385

Canonical Wnt signaling regulates organ-specific assembly and differentiation of CNS vasculature

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5559385

Wnt/beta-catenin signaling controls development of the blood-brain barrier

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5559385

Restoration of p53 function leads to tumour regression in vivo

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5559385

Vascular development of the brain requires beta8 integrin expression in the neuroepithelium

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5559385

Vascular development in the retina and inner ear: control by Norrin and Frizzled-4, a high-affinity ligand-receptor pair

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5559385

Endothelial PDGF-B retention is required for proper investment of pericytes in the microvessel wall

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5559385

Size-selective loosening of the blood-brain barrier in claudin-5-deficient mice

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5559385

Mapping Wnt/beta-catenin signaling during mouse development and in colorectal tumors

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5559385

Comparative evaluation of the antitumor activity of antiangiogenic proteins delivered by gene transfer

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5559385

Intestinal polyposis in mice with a dominant stable mutation of the beta-catenin gene

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5559385

Pericyte loss and microaneurysm formation in PDGF-B-deficient mice

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5559385

In vivo Wnt signaling tracing through a transgenic biosensor fish reveals novel activity domains.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5559385

Frizzled 4 is required for retinal angiogenesis and maintenance of the blood-retina barrier.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5559385

The Reck tumor suppressor protein alleviates tissue damage and promotes functional recovery after transient cerebral ischemia in mice

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5559385

Vascular changes in the cerebellum of Norrin /Ndph knockout mice correlate with high expression of Norrin and Frizzled-4.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5559385

Evaluating therapeutic targets for reperfusion-related brain hemorrhage

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5559385

Mutations in Col4a1 cause perinatal cerebral hemorrhage and porencephaly.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5559385

Neuroprotective function of the PGE2 EP2 receptor in cerebral ischemia.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5559385

Temporal profile of angiogenesis and expression of related genes in the brain after ischemia

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5559385

Glucose transporter glut-1 expression correlates with tumor hypoxia and predicts metastasis-free survival in advanced carcinoma of the cervix

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5559385

News from the brain: the GPR124 orphan receptor directs brain-specific angiogenesis

19 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNM.4309

7 January 2021

inferred from DOI database lookup

Selective ablation of v integrins in the central nervous system leads to cerebral hemorrhage, seizures, axonal degeneration and premature death

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNM.4309

7 January 2021

inferred from DOI database lookup

Reck enables cerebrovascular development by promoting canonical Wnt signaling

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNM.4309

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/NM.4309

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28288111%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

31 May 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28288111%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

PubMed publication ID

28288111

1 reference