(Q41456819)

English

Catalysis of GTP hydrolysis by small GTPases at atomic detail by integration of X-ray crystallography, experimental, and theoretical IR spectroscopy

scientific article published on 13 August 2015

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

30 September 2017

Catalysis of GTP hydrolysis by small GTPases at atomic detail by integration of X-ray crystallography, experimental, and theoretical IR spectroscopy (English)

1 reference

Europe PubMed Central

PMC publication ID

30 September 2017

X-ray crystallography

0 references

RAN, member RAS oncogene family

1 reference

GOA release 2020-03-11

GTP metabolic process

1 reference

GOA release 2020-03-11

5

object named as

Klaus Gerwert

1 reference

Europe PubMed Central

PMC publication ID

30 September 2017

Carsten Kötting

6

object named as

Carsten Kötting

1 reference

Europe PubMed Central

PMC publication ID

30 September 2017

1

object named as

Till Rudack

1 reference

Europe PubMed Central

PMC publication ID

30 September 2017

3

object named as

Sven Brucker

1 reference

Europe PubMed Central

PMC publication ID

30 September 2017

author name string

Sarah Jenrich

2

1 reference

Europe PubMed Central

PMC publication ID

30 September 2017

Ingrid R Vetter

4

1 reference

Europe PubMed Central

PMC publication ID

30 September 2017

language of work or name

0 references

publication date

13 August 2015

1 reference

Europe PubMed Central

PMC publication ID

30 September 2017

number of pages

12

1 reference

based on heuristic

inferred from page(s)

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PMC publication ID

30 September 2017

290

1 reference

Europe PubMed Central

PMC publication ID

30 September 2017

40

1 reference

Europe PubMed Central

PMC publication ID

30 September 2017

24079-24090

1 reference

Europe PubMed Central

PMC publication ID

30 September 2017

GROMACS 4: Algorithms for Highly Efficient, Load-Balanced, and Scalable Molecular Simulation

1 reference

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Regulation of small GTPases by GEFs, GAPs, and GDIs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591799

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Catalytic mechanism of a mammalian Rab⋅RabGAP complex in atomic detail

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591799

30 September 2017

Ras and GTPase-activating protein (GAP) drive GTP into a precatalytic state as revealed by combining FTIR and biomolecular simulations

1 reference

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A comprehensive survey of Ras mutations in cancer

1 reference

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Inhibition and termination of physiological responses by GTPase activating proteins

1 reference

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Ras history: The saga continues

1 reference

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Structure-function relationships of the G domain, a canonical switch motif

1 reference

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The defective nuclear lamina in Hutchinson-gilford progeria syndrome disrupts the nucleocytoplasmic Ran gradient and inhibits nuclear localization of Ubc9.

1 reference

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Nuclear pore complex: biochemistry and biophysics of nucleocytoplasmic transport in health and disease

1 reference

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Conformational states of human rat sarcoma (Ras) protein complexed with its natural ligand GTP and their role for effector interaction and GTP hydrolysis

1 reference

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Effector Proteins Exert an Important Influence on the Signaling-active State of the Small GTPase Cdc42

1 reference

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Molecular mechanism of the nuclear protein import cycle

1 reference

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Structure of the extremely slow GTPase Rab6A in the GTP bound form at 1.8A resolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591799

30 September 2017

GROMACS: fast, flexible, and free

1 reference

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Characterization of Ran-driven cargo transport and the RanGTPase system by kinetic measurements and computer simulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591799

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Understanding the catalytic mechanism of GTPase-activating proteins: demonstration of the importance of switch domain stabilization in the stimulation of GTP hydrolysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591799

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RanGAP mediates GTP hydrolysis without an arginine finger

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591799

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Structure of the metal-water complex in Ras x GDP studied by high-field EPR spectroscopy and 31P NMR spectroscopy

1 reference

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Transport between the cell nucleus and the cytoplasm

1 reference

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The pre-hydrolysis state of p21(ras) in complex with GTP: new insights into the role of water molecules in the GTP hydrolysis reaction of ras-like proteins

1 reference

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The crystal structure of rna1p: a new fold for a GTPase-activating protein

1 reference

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30 September 2017

Structure of a Ran-binding domain complexed with Ran bound to a GTP analogue: implications for nuclear transport

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591799

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Three-dimensional structures of H-ras p21 mutants: molecular basis for their inability to function as signal switch molecules

1 reference

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The role of magnesium for geometry and charge in GTP hydrolysis, revealed by quantum mechanics/molecular mechanics simulations

1 reference

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11 June 2018

Time-resolved FTIR studies of the GTPase reaction of H-ras p21 reveal a key role for the beta-phosphate

1 reference

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Expression of p21 proteins in Escherichia coli and stereochemistry of the nucleotide-binding site

1 reference

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Tyr39 of ran preserves the Ran.GTP gradient by inhibiting GTP hydrolysis

1 reference

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The chromophore structural changes during the photocycle of phytochrome: a combined resonance Raman and quantum chemical approach.

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A novel N-ras mutation in malignant melanoma is associated with excellent prognosis.

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New Photoactivated Protecting Groups. 6.p-Hydroxyphenacyl: A Phototrigger for Chemical and Biochemical Probes1,2

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M115.648071

21 January 2018

The Crystal Structure of rna1p

1 reference

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21 January 2018

Three ways in, one way out: water dynamics in the trans-membrane domains of the inner membrane translocase AcrB

1 reference

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Time-resolved FTIR studies provide activation free energy, activation enthalpy and activation entropy for GTPase reactions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M115.648071

21 January 2018

Surface Change of Ras Enabling Effector Binding Monitored in Real Time at Atomic Resolution

1 reference

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The specific vibrational modes of GTP in solution and bound to Ras: a detailed theoretical analysis by QM/MM simulations

1 reference

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Dynamic and equilibrium studies on the interaction of Ran with its effector, RanBP1

1 reference

https://pubmed.ncbi.nlm.nih.gov/26272610

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inferred from PubMed ID database lookup

Kinetics of interaction of nucleotides with nucleotide-free H-ras p21

1 reference

https://pubmed.ncbi.nlm.nih.gov/26272610

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based on heuristic

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The C terminus of the nuclear RAN/TC4 GTPase stabilizes the GDP-bound state and mediates interactions with RCC1, RAN-GAP, and HTF9A/RANBP1

1 reference

https://pubmed.ncbi.nlm.nih.gov/26272610

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M115.648071

1 reference

Europe PubMed Central

PMC publication ID

30 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

30 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

30 September 2017

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