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Knockdown and replacement therapy mediated by artificial mirtrons in spinocerebellar ataxia 7.
scientific article published on 30 May 2017
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5569705
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21 March 2020
title
Knockdown and replacement therapy mediated by artificial mirtrons in spinocerebellar ataxia 7
(English)
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Europe PubMed Central
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5569705
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21 March 2020
main subject
spinocerebellar ataxia
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Yiqi Seow
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2
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5569705
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21 March 2020
Helen J Curtis
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1
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21 March 2020
Matthew J. Wood
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3
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21 March 2020
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Miguel A Varela
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4
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publication date
1 July 2017
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21 March 2020
published in
Nucleic Acids Research
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21 March 2020
volume
45
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21 March 2020
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13
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21 March 2020
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7870-7885
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21 March 2020
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Creative Commons Attribution 4.0 International
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30 May 2017
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5569705
retrieved
10 June 2018
Impact of RNA structure on the prediction of donor and acceptor splice sites
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5569705
retrieved
10 June 2018
Polycistronic RNA polymerase II expression vectors for RNA interference based on BIC/miR-155.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5569705
retrieved
10 June 2018
Novel Pol II fusion promoter directs human immunodeficiency virus type 1-inducible coexpression of a short hairpin RNA and protein.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5569705
retrieved
10 June 2018
New RNAi strategy for selective suppression of a mutant allele in polyglutamine disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5569705
retrieved
10 June 2018
Argonaute2 cleaves the anti-guide strand of siRNA during RISC activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5569705
retrieved
10 June 2018
Repeat instability: mechanisms of dynamic mutations
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5569705
retrieved
10 June 2018
A combinatorial code for splicing silencing: UAGG and GGGG motifs
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5569705
retrieved
10 June 2018
Post-entrapment genome engineering: first exon size does not affect the expression of fusion transcripts generated by gene entrapment
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5569705
retrieved
10 June 2018
Influence of RNA secondary structure on the pre-mRNA splicing process
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5569705
retrieved
10 June 2018
Promoters and control elements: designing expression cassettes for gene therapy.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5569705
retrieved
10 June 2018
Analysis and recognition of 5' UTR intron splice sites in human pre-mRNA.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5569705
retrieved
10 June 2018
Rational siRNA design for RNA interference
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5569705
retrieved
10 June 2018
Functional siRNAs and miRNAs Exhibit Strand Bias
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5569705
retrieved
10 June 2018
MicroRNAs and small interfering RNAs can inhibit mRNA expression by similar mechanisms
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5569705
retrieved
10 June 2018
A quantitative analysis of intron effects on mammalian gene expression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5569705
retrieved
10 June 2018
Predictive identification of exonic splicing enhancers in human genes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5569705
retrieved
10 June 2018
Gene silencing using micro-RNA designed hairpins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5569705
retrieved
10 June 2018
RNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5569705
retrieved
10 June 2018
Similarities between spinocerebellar ataxia type 7 (SCA7) cell models and human brain: proteins recruited in inclusions and activation of caspase-3.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5569705
retrieved
10 June 2018
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5569705
retrieved
10 June 2018
Splicing of constitutive upstream introns is essential for the recognition of intra-exonic suboptimal splice sites in the thrombopoietin gene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5569705
retrieved
10 June 2018
RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5569705
retrieved
10 June 2018
Statistical features of human exons and their flanking regions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5569705
retrieved
10 June 2018
Cloning of the SCA7 gene reveals a highly unstable CAG repeat expansion
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5569705
retrieved
10 June 2018
G triplets located throughout a class of small vertebrate introns enforce intron borders and regulate splice site selection
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5569705
retrieved
10 June 2018
Short artificial hairpins sequester splicing signals and inhibit yeast pre-mRNA splicing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5569705
retrieved
10 June 2018
Exon recognition in vertebrate splicing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5569705
retrieved
10 June 2018
Control of adenovirus E1B mRNA synthesis by a shift in the activities of RNA splice sites
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5569705
retrieved
10 June 2018
Transfer of genetic therapy across human populations: molecular targets for increasing patient coverage in repeat expansion diseases.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5569705
retrieved
19 August 2018
Artificial miRNAs Targeting Mutant Huntingtin Show Preferential Silencing In Vitro and In Vivo.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5569705
retrieved
19 August 2018
In vivo application of an RNAi strategy for the selective suppression of a mutant allele
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5569705
retrieved
19 August 2018
Expression of shRNA from a tissue-specific pol II promoter is an effective and safe RNAi therapeutic
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5569705
retrieved
19 August 2018
Structural determinants of RNA recognition and cleavage by Dicer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5569705
retrieved
19 August 2018
A genetic strategy to treat sickle cell anemia by coregulating globin transgene expression and RNA interference
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5569705
retrieved
19 August 2018
Toward a gene therapy for dominant disease: validation of an RNA interference-based mutation-independent approach
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5569705
retrieved
19 August 2018
An RNAi strategy for treatment of amyotrophic lateral sclerosis caused by mutant Cu,Zn superoxide dismutase.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5569705
retrieved
19 August 2018
Computational identification of promoters and first exons in the human genome
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/28575281
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Ribozyme-based therapeutic approaches for autosomal dominant retinitis pigmentosa
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/28575281
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1093/NAR/GKX483
1 reference
stated in
Europe PubMed Central
PMCID
5569705
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28575281%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 March 2020
PMCID
5569705
1 reference
stated in
Europe PubMed Central
PMCID
5569705
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28575281%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 March 2020
PubMed ID
28575281
1 reference
stated in
Europe PubMed Central
PMCID
5569705
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28575281%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 March 2020
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