(Q41516895)

2 October 2017

The antibiotic Furvina® targets the P-site of 30S ribosomal subunits and inhibits translation initiation displaying start codon bias (English)

1 reference

2 October 2017

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3

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2 October 2017

1

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Claudio O Gualerzi

7

object named as

Claudio O Gualerzi

1 reference

2 October 2017

4

Cynthia L Pon

1 reference

2 October 2017

Attilio Fabbretti

1

1 reference

2 October 2017

Letizia Brandi

2

1 reference

2 October 2017

Nilo R Castañedo

5

1 reference

2 October 2017

Ricardo Medina

6

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2 October 2017

language of work or name

1 reference

31 August 2012

1 reference

2 October 2017

Nucleic Acids Research

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2 October 2017

40

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2 October 2017

20

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2 October 2017

10366-10374

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Creative Commons Attribution-NonCommercial 3.0 Unported

2 October 2017

start time

7 November 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Role of helix 44 of 16S rRNA in the fidelity of translation initiation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488254

Differential effects of thiopeptide and orthosomycin antibiotics on translational GTPases

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488254

How to cope with the quest for new antibiotics.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488254

Novel small molecule inhibitors of MDR Mycobacterium tuberculosis by NMR fragment screening of antigen 85C.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488254

The A-Z of bacterial translation inhibitors

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488254

Fragment-based discovery of selective inhibitors of the Mycobacterium tuberculosis protein tyrosine phosphatase PtpA.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488254

In vitro bactericidal activity of iclaprim in human plasma

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488254

Discovery of antibacterial biotin carboxylase inhibitors by virtual screening and fragment-based approaches

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488254

Control of translation initiation involves a factor-induced rearrangement of helix 44 of 16S ribosomal RNA

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488254

Bad bugs, no drugs: no ESKAPE! An update from the Infectious Diseases Society of America

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488254

Assays for the identification of inhibitors targeting specific translational steps

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488254

Characterization of 16S rRNA mutations that decrease the fidelity of translation initiation

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488254

Methods for identifying compounds that specifically target translation

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488254

A quantitative kinetic scheme for 70 S translation initiation complex formation

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488254

Molecular mechanisms of antibacterial multidrug resistance

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488254

Structure of the 70S ribosome complexed with mRNA and tRNA

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488254

Specific, efficient, and selective inhibition of prokaryotic translation initiation by a novel peptide antibiotic

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488254

Mode of action and biochemical characterization of REP8839, a novel inhibitor of methionyl-tRNA synthetase

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488254

Translation initiation factor IF3: two domains, five functions, one mechanism?

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488254

Altered discrimination of start codons and initiator tRNAs by mutant initiation factor 3

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488254

Structure of functionally activated small ribosomal subunit at 3.3 angstroms resolution

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488254

In vitro evaluation of G1: a novel antimicrobial compound

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488254

Crystal structure of the anti-bacterial sulfonamide drug target dihydropteroate synthase

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488254

Escherichia coli translation initiation factor 3 discriminates the initiation codon in vivo

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488254

The role of the AUU initiation codon in the negative feedback regulation of the gene for translation initiation factor IF3 in Escherichia coli.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488254

Translation of mRNAs with degenerate initiation triplet AUU displays high initiation factor 2 dependence and is subject to initiation factor 3 repression

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488254

Effect of Initiation Factor 3 Binding on the 30S Ribosomal Subunits of Escherichia coli

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488254

Temperature-sensitive mutation in the initiation codon of the rIIB gene of bacteriophage T4

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488254

Specificity and Properties of the Destabilization, Induced by Initiation Factor IF-3, of Ternary Complexes of the 30-S Ribosomal Subunit, Aminoacyl-tRNA and Polynucleotides

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488254

Real-time dynamics of ribosome-ligand interaction by time-resolved chemical probing methods

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488254

Transient kinetics, fluorescence, and FRET in studies of initiation of translation in bacteria

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488254

The real-time path of translation factor IF3 onto and off the ribosome.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488254

Novel tetrapeptide inhibitors of bacterial protein synthesis produced by a Streptomyces sp.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488254

Involvement of 16S rRNA nucleotides G1338 and A1339 in discrimination of initiator tRNA.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488254

The translation initiation functions of IF2: targets for thiostrepton inhibition.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488254

Initiation of protein synthesis: a target for antimicrobials

19 August 2018

1 reference

12 December 2020

Kinetic Checkpoint at a Late Step in Translation Initiation

1 reference

12 December 2020

The topographical localization of IF3 on Escherichia coli 30 S ribosomal subunits as a clue to its way of functioning

1 reference

12 December 2020

Late events in translation initiation. Adjustment of fMet-tRNA in the ribosomal P-site

1 reference

12 December 2020

Identifiers

DOI

10.1093/NAR/GKS822

1 reference

2 October 2017

1 reference

2 October 2017

PubMed publication ID

22941660

1 reference