(Q41722127)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9505089%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

review article

1 reference

title

Prenylation of Ras GTPase superfamily proteins and their function in immunobiology (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9505089%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

author name string

R B Lobell

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9505089%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

publication date

1 January 1998

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9505089%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

published in

Advances in Immunology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9505089%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

volume

68

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9505089%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

page(s)

145-189

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9505089%20AND%20SRC:MED&resulttype=core&format=json

Activation of the NADPH oxidase involves the small GTP-binding protein p21rac1

10 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Activation of NADPH oxidase involves the dissociation of p21rac from its inhibitory GDP/GTP exchange protein (rhoGDI) followed by its translocation to the plasma membrane.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Phosphatidic acid as a second messenger in human polymorphonuclear leukocytes. Effects on activation of NADPH oxidase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Inhibition of protein prenylation down-regulates signalling by inflammatory mediators in human keratinocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

cDNA cloning of component A of Rab geranylgeranyl transferase and demonstration of its role as a Rab escort protein

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Activation of exocytosis by the heterotrimeric G protein Gi3

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Sp1 is phosphorylated and its DNA binding activity down-regulated upon terminal differentiation of the liver

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

1 reference

7 January 2021

The structure of the GTPase-activating domain from p50rhoGAP

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Novel tricyclic inhibitors of farnesyl protein transferase. Biochemical characterization and inhibition of Ras modification in transfected Cos cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Proteins regulating Ras and its relatives

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Rab4 and Rab7 define distinct nonoverlapping endosomal compartments

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

The GTPase superfamily: conserved structure and molecular mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Modulation of Ras and a-factor function by carboxyl-terminal proteolysis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

GTP-binding proteins in polymorphonuclear granulocytes of severely burned patients.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Tetrapeptide inhibitors of protein farnesyltransferase: amino-terminal substitution in phenylalanine-containing tetrapeptides restores farnesylation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Mapping of the C5a receptor signal transduction network in human neutrophils

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

A conserved binding motif defines numerous candidate target proteins for both Cdc42 and Rac GTPases

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Regulation of Ras-mediated signalling: more than one way to skin a cat.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Activation of the cellular proto-oncogene product p21Ras by addition of a myristylation signal

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Signal transduction by the B cell antigen receptor and its coreceptors

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

p21ras is modified by a farnesyl isoprenoid

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Enzymatic modification of proteins with a geranylgeranyl isoprenoid

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Prenylation of oncogenic human PTP(CAAX) protein tyrosine phosphatases

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Calcium-dependent immediate-early gene induction in lymphocytes is negatively regulated by p21Ha-ras

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Cloning and expression of a cDNA encoding the alpha subunit of rat p21ras protein farnesyltransferase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

cDNA cloning and expression of the peptide-binding β subunit of rat p21rasfarnesyltransferase, the counterpart of yeast DPR1/RAM1

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Solubilization, partial purification, and affinity labeling of the membrane-bound isoprenylated protein endoprotease

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Interferon-induced guanylate-binding proteins lack an N(T)KXD consensus motif and bind GMP in addition to GDP and GTP

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

The 70 kDa S6 kinase complexes with and is activated by the Rho family G proteins Cdc42 and Rac1.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Two cytosolic components of the human neutrophil respiratory burst oxidase translocate to the plasma membrane during cell activation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Amino acid substitutions that convert the protein substrate specificity of farnesyltransferase to that of geranylgeranyltransferase type I.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Activation of mitogen-activated protein kinase kinase by v-Raf in NIH 3T3 cells and in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Isolation of a novel gene mutated in Wiskott-Aldrich syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Geranylgeranylation of Rab proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Interaction of Rac with p67phox and regulation of phagocytic NADPH oxidase activity

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

The respiratory burst oxidase and the molecular genetics of chronic granulomatous disease

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Purification of a protein palmitoyltransferase that acts on H-Ras protein and on a C-terminal N-Ras peptide

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Protein-DNA interactions at a drug-responsive element of the human apolipoprotein A-I gene

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Rab geranylgeranyl transferase catalyzes the geranylgeranylation of adjacent cysteines in the small GTPases Rab1A, Rab3A, and Rab5A

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Capacitance measurements reveal stepwise fusion events in degranulating mast cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

p190 RhoGAP, the major RasGAP-associated protein, binds GTP directly

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Ligation of the T cell receptor complex results in activation of the Ras/Raf-1/MEK/MAPK cascade in human T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Activation of multiple protein kinases including a MAP kinase upon Fc epsilon RI cross-linking

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Mutational and kinetic analyses of the GTPase-activating protein (GAP)-p21 interaction: the C-terminal domain of GAP is not sufficient for full activity

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Aberrant function of the Ras-related protein TC21/R-Ras2 triggers malignant transformation.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

FAS-induced apoptosis is mediated via a ceramide-initiated RAS signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Fas-induced programmed cell death is mediated by a Ras-regulated O2- synthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

All ras proteins are polyisoprenylated but only some are palmitoylated

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

A polybasic domain or palmitoylation is required in addition to the CAAX motif to localize p21ras to the plasma membrane

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

A CAAX or a CAAL motif and a second signal are sufficient for plasma membrane targeting of ras proteins.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Identification of Ras farnesyltransferase inhibitors by microbial screening

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Requirement for posttranslational processing of Rac GTP-binding proteins for activation of human neutrophil NADPH oxidase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

The role of prenylation in G-protein assembly and function

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Activation of the MAP kinase pathway by the protein kinase raf

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Farnesyl cysteine C-terminal methyltransferase activity is dependent upon the STE14 gene product in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Evidence for a catalytic role of zinc in protein farnesyltransferase. Spectroscopy of Co2+-farnesyltransferase indicates metal coordination of the substrate thiolate

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Potent, cell active, non-thiol tetrapeptide inhibitors of farnesyltransferase.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Protein prenylcysteine analog inhibits agonist-receptor-mediated signal transduction in human platelets

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Mitogenic signaling mediated by oxidants in Ras-transformed fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

p21ras couples the T cell antigen receptor to extracellular signal-regulated kinase 2 in T lymphocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

The role of Raf-1 in the regulation of extracellular signal-regulated kinase 2 by the T cell antigen receptor.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Resistance of K-RasBV12 proteins to farnesyltransferase inhibitors in Rat1 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Benzodiazepine peptidomimetics: potent inhibitors of Ras farnesylation in animal cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Mutagenesis of active site residues in type I dehydroquinase from Escherichia coli. Stalled catalysis in a histidine to alanine mutant.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

The GTPase Rab3a negatively controls calcium-dependent exocytosis in neuroendocrine cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

RAC regulation of actin polymerization and proliferation by a pathway distinct from Jun kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Stimulation of membrane ruffling and MAP kinase activation by distinct effectors of RAS.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Isoprenoid addition to Ras protein is the critical modification for its membrane association and transforming activity

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Oncogenic Ras activation of Raf/mitogen-activated protein kinase-independent pathways is sufficient to cause tumorigenic transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Efficient interaction with a receptor requires a specific type of prenyl group on the G protein gamma subunit

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Regulation of phagocyte oxygen radical production by the GTP-binding protein Rac 2

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Selective inhibition of ras-dependent transformation by a farnesyltransferase inhibitor

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Protein farnesyltransferase inhibitors block the growth of ras-dependent tumors in nude mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Inhibition of farnesyltransferase induces regression of mammary and salivary carcinomas in ras transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

The ksr-1 gene encodes a novel protein kinase involved in Ras-mediated signaling in C. elegans

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Membrane association of Rac is required for high activity of the respiratory burst oxidase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

The effect of posttranslational modifications on the interaction of Ras2 with adenylyl cyclase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

ADP-ribosylation factor functions synergistically with a 50-kDa cytosolic factor in cell-free activation of human neutrophil phospholipase D.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Raf-1 activates MAP kinase-kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

GAPs for rho-related GTPases

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Rac and Cdc42 induce actin polymerization and G1 cell cycle progression independently of p65PAK and the JNK/SAPK MAP kinase cascade

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Regulation of receptor-mediated endocytosis by Rho and Rac.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Role of Rho in chemoattractant-activated leukocyte adhesion through integrins

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Evidence that farnesyltransferase inhibitors suppress Ras transformation by interfering with Rho activity

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Differential expression of the ras gene family in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Disruption of oncogenic K-Ras4B processing and signaling by a potent geranylgeranyltransferase I inhibitor

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Inhibition of Rab3B expression attenuates Ca(2+)-dependent exocytosis in rat anterior pituitary cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Function and regulation of ras.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Inhibitors of the isoprenylated protein endoprotease

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Mechanistic studies on human platelet isoprenylated protein methyltransferase: farnesylcysteine analogs block platelet aggregation without inhibiting the methyltransferase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Evidence for Rho-mediated agonist stimulation of phospholipase D in rat1 fibroblasts. Effects of Clostridium botulinum C3 exoenzyme.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

A non-receptor tyrosine kinase that inhibits the GTPase activity of p21cdc42

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Activation of phospholipase D and phosphatidylinositol 4-phosphate 5-kinase in HL60 membranes is mediated by endogenous Arf but not Rho

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Platelet-derived growth factor receptor tyrosine phosphorylation requires protein geranylgeranylation but not farnesylation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Selective activation of the JNK signaling cascade and c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

T cell lines characterize events in the pathogenesis of the Wiskott-Aldrich syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Complexes of Ras.GTP with Raf-1 and mitogen-activated protein kinase kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

G protein gamma subunits contain a 20-carbon isoprenoid

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Endosome dynamics regulated by a Rho protein.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Prenylation of an interferon-gamma-induced GTP-binding protein: the human guanylate binding protein, huGBP1

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Regulation and function of the Rho subfamily of small GTPases

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

GTPases: multifunctional molecular switches regulating vesicular traffic

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

The dynamics of exocytosis in human neutrophils

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Intracellular application of guanosine-5'-O-(3-thiotriphosphate) induces exocytotic granule fusion in guinea pig eosinophils

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Exocytotic fusion is activated by Rab3a peptides

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

RT-PCR cloning of Rab3 isoforms expressed in peritoneal mast cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Suppression of yeast geranylgeranyl transferase I defect by alternative prenylation of two target GTPases, Rho1p and Cdc42p

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Effect of Clostridium difficile toxin B on IgE receptor-mediated signal transduction in rat basophilic leukemia cells: inhibition of phospholipase D activation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Characterization of recombinant human farnesyl-protein transferase: cloning, expression, farnesyl diphosphate binding, and functional homology with yeast prenyl-protein transferases

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

T cell activation via the disialoganglioside GD3: analysis of signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Functional significance of G protein carboxymethylation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Functional significance of beta gamma-subunit carboxymethylation for the activation of phospholipase C and phosphoinositide 3-kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Crystal structure of protein farnesyltransferase at 2.25 angstrom resolution

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Purified cytochrome b from human granulocyte plasma membrane is comprised of two polypeptides with relative molecular weights of 91,000 and 22,000

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

The regulation and function of p21ras during T-cell activation and growth.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Phosphinyl acid-based bisubstrate analog inhibitors of Ras farnesyl protein transferase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Rac mediates growth factor-induced arachidonic acid release.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Rab GTPases: master regulators of membrane trafficking

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Rab GDP dissociation inhibitor: putting rab GTPases in the right place.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Carboxyl methylation of Ras-related proteins during signal transduction in neutrophils

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Activation-dependent carboxyl methylation of neutrophil G-protein gamma subunit

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

RAM, a gene of yeast required for a functional modification of RAS proteins and for production of mating pheromone a-factor

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Farnesyltransferase inhibition causes morphological reversion of ras-transformed cells by a complex mechanism that involves regulation of the actin cytoskeleton

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

G protein-coupled chemoattractant receptors regulate Lyn tyrosine kinase.Shc adapter protein signaling complexes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

A role for Rho in Ras transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

An essential role for Rac in Ras transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Guanine nucleotide exchange factors: activators of the Ras superfamily of proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Association of a Ras-related protein with cytochrome b of human neutrophils

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

NF-ATp: a transcription factor required for the co-ordinate induction of several cytokine genes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Prenylcysteine analogs mimicking the C-terminus of GTP-binding proteins stimulate exocytosis from permeabilized HIT-T15 cells: comparison with the effect of Rab3AL peptide.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Inhibition of purified p21ras farnesyl:protein transferase by Cys-AAX tetrapeptides

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Sequence requirement for peptide recognition by rat brain p21ras protein farnesyltransferase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

GTPase activity of Rab5 acts as a timer for endocytic membrane fusion

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Genetic and pharmacological suppression of oncogenic mutations in ras genes of yeast and humans.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Structure and mutational analysis of Rab GDP-dissociation inhibitor

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Crystal structure of the GTPase-activating domain of human p120GAP and implications for the interaction with Ras

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Genomic cloning and characterization of the human thrombin receptor gene. Structural similarity to the proteinase activated receptor-2 gene

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

A study of the Influence of mevalonic acid and its metabolites on the morphology of swiss 3T3 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Protein farnesyltransferase and geranylgeranyltransferase share a common alpha subunit

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Deficient geranylgeranylation of Ram/Rab27 in choroideremia.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Mechanism of digeranylgeranylation of Rab proteins. Formation of a complex between monogeranylgeranyl-Rab and Rab escort protein

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

GRB2 and phospholipase C-gamma 1 associate with a 36- to 38-kilodalton phosphotyrosine protein after T-cell receptor stimulation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Fluorimetric evaluation of the affinities of isoprenylated peptides for lipid bilayers.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Coexpression of MMTV/v-Ha-ras and MMTV/c-myc genes in transgenic mice: synergistic action of oncogenes in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Geranylgeranylated Rab proteins terminating in Cys-Ala-Cys, but not Cys-Cys, are carboxyl-methylated by bovine brain membranes in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Membrane targeting of the small GTPase Rab9 is accompanied by nucleotide exchange

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Rab7 and Rab9 are recruited onto late endosomes by biochemically distinguishable processes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

ADP-ribosylation of a small size GTP-binding protein in bovine neutrophils by the C3 exoenzyme of Clostridium botulinum and effect on the cell motility

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Activation of Raf as a result of recruitment to the plasma membrane

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

On the crawling of animal cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Regulation of the polarization of T cells toward antigen-presenting cells by Ras-related GTPase CDC42

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

The C. elegans ksr-1 gene encodes a novel Raf-related kinase involved in Ras-mediated signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Wiskott-Aldrich syndrome protein, a novel effector for the GTPase CDC42Hs, is implicated in actin polymerization

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Identification of an isoprenylated cysteine methyl ester hydrolase activity in bovine rod outer segment membranes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

KSR, a novel protein kinase required for RAS signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Inhibition of PMA-induced, LFA-1-dependent lymphocyte aggregation by ADP ribosylation of the small molecular weight GTP binding protein, rho.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Ras signaling in tumor necrosis factor-induced apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Genetic evidence for in vivo cross-specificity of the CaaX-box protein prenyltransferases farnesyltransferase and geranylgeranyltransferase-I in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Distinct Ras effector pathways are involved in Fc epsilon R1 regulation of the transcriptional activity of Elk-1 and NFAT in mast cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

The alpha 6A beta 1 and alpha 6B beta 1 integrin variants signal differences in the tyrosine phosphorylation of paxillin and other proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Membrane association of Rab5 mediated by GDP-dissociation inhibitor and accompanied by GDP/GTP exchange

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Lovastatin inhibits gene expression of type-I scavenger receptor in THP-1 human macrophages

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Complex formation between RAS and RAF and other protein kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Subcellular localization of the small GTPase Rab5a in resting and stimulated human neutrophils.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

A non-peptide mimetic of Ras-CAAX: selective inhibition of farnesyltransferase and Ras processing

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Mammalian Ras interacts directly with the serine/threonine kinase Raf

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Selection of potent inhibitors of farnesyl-protein transferase from a synthetic tetrapeptide combinatorial library

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Signal transduction by lymphocyte antigen receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Multiple Ras functions can contribute to mammalian cell transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

2-substituted piperazines as constrained amino acids. Application to the synthesis of potent, non carboxylic acid inhibitors of farnesyltransferase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Association of Rab1B with GDP-dissociation inhibitor (GDI) is required for recycling but not initial membrane targeting of the Rab protein

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

FMLP activates Ras and Raf in human neutrophils. Potential role in activation of MAP kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Structural insights into the function of the Rab GDI superfamily

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

The molecular chaperone Ydj1 is required for the p34CDC28-dependent phosphorylation of the cyclin Cln3 that signals its degradation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Phosphorylation of Raf by ceramide-activated protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

A protein geranylgeranyltransferase from bovine brain: implications for protein prenylation specificity

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Functional analysis of microphthalmia-associated transcription factor in pigment cell-specific transcription of the human tyrosinase family genes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Protein prenylation: molecular mechanisms and functional consequences

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Characterization of Ha-ras, N-ras, Ki-Ras4A, and Ki-Ras4B as in vitro substrates for farnesyl protein transferase and geranylgeranyl protein transferase type I

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Kinase suppressor of Ras is ceramide-activated protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

A small GTP-binding protein, Rho, associates with the platelet-derived growth factor type-beta receptor upon ligand binding.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

Isoprenylation mediates direct protein-protein interactions between hepatitis large delta antigen and hepatitis B virus surface antigen.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960559-3

7 January 2021

10.1016/S0065-2776(08)60559-3

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9505089%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

1 reference