(Q41742888)

8 October 2017

title

Antinociceptive effects of morphine-6-glucuronide in homozygous MDR1a P-glycoprotein knockout and in wildtype mice in the hotplate test (English)

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8 October 2017

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2

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8 October 2017

J Lötsch

1

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author name string

M S Angst

series ordinal

3

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8 October 2017

G Geisslinger

series ordinal

4

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8 October 2017

language of work or name

English

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publication date

1 May 2000

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8 October 2017

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8 October 2017

volume

66

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8 October 2017

issue

24

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8 October 2017

page(s)

2393-2403

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Analgesic Effect of Morphine Glucuronides

8 October 2017

cites work

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https://api.crossref.org/works/10.1016%2FS0024-3205%2800%2900569-5

Evidence for P-glycoprotein-modulated penetration of morphine-6-glucuronide into brain capillary endothelium

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2800%2900569-5

The mdrl gene, responsible for multidrug-resistance, codes for P-glycoprotein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2800%2900569-5

P-glycoprotein as the drug efflux pump in primary cultured bovine brain capillary endothelial cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2800%2900569-5

The pharmacological role of P-glycoprotein in the intestinal epithelium

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2800%2900569-5

Inhibition of P-glycoprotein-mediated drug transport: A unifying mechanism to explain the interaction between digoxin and quinidine [seecomments]

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2800%2900569-5

Absence of the mdr1a P-Glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2800%2900569-5

Long lasting respiratory depression induced by morphine-6-glucuronide?

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0024-3205%2800%2900569-5

Morphine intoxication in renal failure: the role of morphine-6-glucuronide

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2800%2900569-5

Pharmacokinetics of morphine and its glucuronides after intravenous infusion of morphine and morphine-6-glucuronide in healthy volunteers*

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2800%2900569-5

Antinociceptive and ventilatory effects of the morphine metabolites: morphine-6-glucuronide and morphine-3-glucuronide

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2800%2900569-5

Lack of Analgesic Activity of Morphine-6-glucuronide after Short-term Intravenous Administration in Healthy Volunteers

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0024-3205%2800%2900569-5

Molecular biology of P-glycoprotein

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0024-3205%2800%2900569-5

Contribution of P-glycoprotein to bunitrolol efflux across blood-brain barrier

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2800%2900569-5

Comparisons of P‐glycoprotein expression in isolated rat brain microvessels and in primary cultures of endothelial cells derived from microvasculature of rat brain, epididymal fat pad and from aorta

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2800%2900569-5

Functional characterization of the rat mdr1b encoded P-glycoprotein: not all inducing agents are substrates

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2800%2900569-5

Role of blood-brain barrier P-glycoprotein in limiting brain accumulation and sedative side-effects of asimadoline, a peripherally acting analgaesic drug

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2800%2900569-5

Lack of tolerance in peripheral opioid analgesia in mice

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0024-3205%2800%2900569-5

Loperamide effects on hepatobiliary function, intestinal transit and analgesia in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2800%2900569-5

Characterization of the antihyperalgesic action of a novel peripheral mu-opioid receptor agonist--loperamide

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2800%2900569-5

P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2800%2900569-5

Substantial excretion of digoxin via the intestinal mucosa and prevention of long-term digoxin accumulation in the brain by the mdr 1a P-glycoprotein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2800%2900569-5

Normal development of mice and unimpaired cell adhesion/cell motility/actin-based cytoskeleton without compensatory up-regulation of ezrin or radixin in moesin gene knockout

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2800%2900569-5

Compensatory expression of p73 in PARP-deficient mouse fibroblasts as response to a reduced level of regularly spliced wild-type p53 protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2800%2900569-5

Loss of cytoskeletal support is not sufficient for anoxic plasma membrane disruption in renal cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2800%2900569-5

P-glycoprotein-mediated transport of itraconazole across the blood-brain barrier.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2800%2900569-5

Biliary secretion of alpha-tocopherol and the role of the mdr2 P-glycoprotein in rats and mice.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2800%2900569-5

Effect of GF120918, a potent P-glycoprotein inhibitor, on morphine pharmacokinetics and pharmacodynamics in the rat

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2800%2900569-5

10.1016/S0024-3205(00)00569-5

7 January 2021

Identifiers

DOI

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8 October 2017

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