(Q41768080)

9 October 2017

A FAK-p120RasGAP-p190RhoGAP complex regulates polarity in migrating cells (English)

1 reference

9 October 2017

Alok Tomar

1

1 reference

9 October 2017

Ssang-Taek Lim

series ordinal

2

1 reference

9 October 2017

Yangmi Lim

series ordinal

3

1 reference

9 October 2017

David D Schlaepfer

series ordinal

4

1 reference

9 October 2017

language of work or name

English

0 references

publication date

12 May 2009

1 reference

9 October 2017

11

1 reference

inferred from page(s)

published in

Journal of Cell Science

1 reference

9 October 2017

122

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9 October 2017

Pt 11

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9 October 2017

1852-1862

1 reference

describes a project that uses

9 October 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2684836/fullTextXML

inferred from PubMed Central ID database lookup

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p190A RhoGAP is a glycogen synthase kinase-3-beta substrate required for polarized cell migration

6 June 2018

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The PAR-6 polarity protein regulates dendritic spine morphogenesis through p190 RhoGAP and the Rho GTPase

6 June 2018

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PyK2 and FAK connections to p190Rho guanine nucleotide exchange factor regulate RhoA activity, focal adhesion formation, and cell motility

6 June 2018

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6 June 2018

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6 June 2018

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6 June 2018

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6 June 2018

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6 June 2018

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6 June 2018

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Caveolin-1 regulates cell polarization and directional migration through Src kinase and Rho GTPases

6 June 2018

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Tumor necrosis factor-alpha stimulates focal adhesion kinase activity required for mitogen-activated kinase-associated interleukin 6 expression

6 June 2018

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Cellular characterization of a novel focal adhesion kinase inhibitor

6 June 2018

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Focal adhesion kinase modulates tension signaling to control actin and focal adhesion dynamics

6 June 2018

1 reference

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Integrin signaling through Arg activates p190RhoGAP by promoting its binding to p120RasGAP and recruitment to the membrane

6 June 2018

1 reference

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Integrin-regulated FAK-Src signaling in normal and cancer cells

6 June 2018

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Intrinsic FAK activity and Y925 phosphorylation facilitate an angiogenic switch in tumors

6 June 2018

1 reference

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Spatiotemporal dynamics of RhoA activity in migrating cells

6 June 2018

1 reference

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Intrinsic focal adhesion kinase activity controls orthotopic breast carcinoma metastasis via the regulation of urokinase plasminogen activator expression in a syngeneic tumor model.

6 June 2018

1 reference

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Suppression of RhoA activity by focal adhesion kinase-induced activation of p190RhoGAP: role in regulation of endothelial permeability

6 June 2018

1 reference

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Cell migration at a glance

6 June 2018

1 reference

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Rho GTPases and the control of cell behaviour

6 June 2018

1 reference

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6 June 2018

1 reference

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Focal adhesion kinase is required for the spatial organization of the leading edge in migrating cells

6 June 2018

1 reference

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Focal adhesion kinase: in command and control of cell motility

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684836

Coordinating cytoskeletal tracks to polarize cellular movements

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684836

Loss of caveolin-1 polarity impedes endothelial cell polarization and directional movement

6 June 2018

1 reference

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Control of motile and invasive cell phenotypes by focal adhesion kinase.

6 June 2018

1 reference

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GAP control: regulating the regulators of small GTPases

6 June 2018

1 reference

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Adhesion-dependent regulation of p190RhoGAP in the developing brain by the Abl-related gene tyrosine kinase

6 June 2018

1 reference

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Overexpression of FAK promotes Ras activity through the formation of a FAK/p120RasGAP complex in malignant astrocytoma cells

6 June 2018

1 reference

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Cell migration: integrating signals from front to back

6 June 2018

1 reference

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Differential regulation of cell motility and invasion by FAK

6 June 2018

1 reference

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Localized suppression of RhoA activity by Tyr31/118-phosphorylated paxillin in cell adhesion and migration

6 June 2018

1 reference

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Src-mediated coupling of focal adhesion kinase to integrin alpha(v)beta5 in vascular endothelial growth factor signaling.

6 June 2018

1 reference

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The role of the dynamics of focal adhesion kinase in the mechanotaxis of endothelial cells

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684836

Focal adhesion kinase is involved in mechanosensing during fibroblast migration

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684836

RhoA inactivation by p190RhoGAP regulates cell spreading and migration by promoting membrane protrusion and polarity

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684836

Targeting Pyk2 to beta 1-integrin-containing focal contacts rescues fibronectin-stimulated signaling and haptotactic motility defects of focal adhesion kinase-null cells

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684836

Role of p120 Ras-GAP in directed cell movement

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684836

Shc and FAK differentially regulate cell motility and directionality modulated by PTEN.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684836

Required role of focal adhesion kinase (FAK) for integrin-stimulated cell migration

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684836

Aberrant Ras regulation and reduced p190 tyrosine phosphorylation in cells lacking p120-Gap

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684836

Tandem SH2 binding sites mediate the RasGAP-RhoGAP interaction: a conformational mechanism for SH3 domain regulation

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684836

The N-terminal region of GAP regulates cytoskeletal structure and cell adhesion

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684836

Two SH2 Domains of p120 Ras GTPase-activating Protein Bind Synergistically to Tyrosine Phosphorylated p190 Rho GTPase-activating Protein

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684836

Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684836

c-Src regulates the simultaneous rearrangement of actin cytoskeleton, p190RhoGAP, and p120RasGAP following epidermal growth factor stimulation

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684836

Preferential phosphorylation of focal adhesion kinase tyrosine 861 is critical for mediating an anti-apoptotic response to hyperosmotic stress

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684836

v-Src rescues actin-based cytoskeletal architecture and cell motility and induces enhanced anchorage independence during oncogenic transformation of focal adhesion kinase-null fibroblasts

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684836

A role for alphabeta1 integrins in focal adhesion function and polarized cytoskeletal dynamics

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684836

Focal adhesion kinase suppresses Rho activity to promote focal adhesion turnover

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684836

Regulation of p190 Rho-GAP by v-Src is linked to cytoskeletal disruption during transformation.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2684836

Integrin engagement suppresses RhoA activity via a c-Src-dependent mechanism

18 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19435801

12 December 2020

inferred from PubMed ID database lookup

Integrin α3β1-Dependent Activation of FAK/Src Regulates Rac1-Mediated Keratinocyte Polarization on Laminin-5

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19435801

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1242/JCS.046870

1 reference

9 October 2017

1 reference

9 October 2017

PubMed publication ID

19435801

1 reference