(Q41788288)

English

G-quadruplex folds of the human telomere sequence alter the site reactivity and reaction pathway of guanine oxidation compared to duplex DNA.

scientific article published on 13 March 2013

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

9 October 2017

G-quadruplex folds of the human telomere sequence alter the site reactivity and reaction pathway of guanine oxidation compared to duplex DNA. (English)

1 reference

Europe PubMed Central

PMC publication ID

9 October 2017

Cynthia J. Burrows

2

object named as

Cynthia J Burrows

1 reference

Europe PubMed Central

PMC publication ID

9 October 2017

author name string

Aaron M Fleming

1

1 reference

Europe PubMed Central

PMC publication ID

9 October 2017

publication date

13 March 2013

1 reference

Europe PubMed Central

PMC publication ID

9 October 2017

Chemical Research in Toxicology

1 reference

Europe PubMed Central

PMC publication ID

9 October 2017

26

1 reference

Europe PubMed Central

PMC publication ID

9 October 2017

4

1 reference

Europe PubMed Central

PMC publication ID

9 October 2017

593-607

1 reference

Europe PubMed Central

PMC publication ID

9 October 2017

Quantitative visualization of DNA G-quadruplex structures in human cells

1 reference

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Comparative analysis of four oxidized guanine lesions from reactions of DNA with peroxynitrite, singlet oxygen, and γ-radiation

1 reference

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1 reference

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1 reference

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Structural context effects in the oxidation of 8-oxo-7,8-dihydro-2'-deoxyguanosine to hydantoin products: electrostatics, base stacking, and base pairing

1 reference

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8-Oxo-2'-deoxyguanosine as a biomarker of tobacco-smoking-induced oxidative stress

1 reference

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Promoter G-quadruplex sequences are targets for base oxidation and strand cleavage during hypoxia-induced transcription

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Proton-coupled hole hopping in nucleosomal and free DNA initiated by site-specific hole injection

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Lifetimes and reaction pathways of guanine radical cations and neutral guanine radicals in an oligonucleotide in aqueous solutions.

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Chemical and biological consequences of oxidatively damaged guanine in DNA.

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A qPCR-based assay to quantify oxidized guanine and other FPG-sensitive base lesions within telomeric DNA.

1 reference

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Sequence-dependent variation in the reactivity of 8-Oxo-7,8-dihydro-2'-deoxyguanosine toward oxidation

1 reference

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Structure and stability of higher-order human telomeric quadruplexes

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Endonuclease VIII-like 3 (Neil3) DNA glycosylase promotes neurogenesis induced by hypoxia-ischemia

1 reference

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Hidden in plain sight: subtle effects of the 8-oxoguanine lesion on the structure, dynamics, and thermodynamics of a 15-base pair oligodeoxynucleotide duplex

1 reference

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DNA secondary structures and epigenetic determinants of cancer genome evolution

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Solvent exposure associated with single abasic sites alters the base sequence dependence of oxidation of guanine in DNA in GG sequence contexts

1 reference

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Fluorescent and luminescent probes for detection of reactive oxygen and nitrogen species.

1 reference

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Structure of human telomeric DNA in crowded solution

1 reference

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Comparison of Transition Metal-Mediated Oxidation Reactions of Guanine in Nucleoside and Single-Stranded Oligodeoxynucleotide Contexts

1 reference

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Leukocyte telomere length in major depression: correlations with chronicity, inflammation and oxidative stress--preliminary findings

1 reference

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Characterization of 2'-deoxyguanosine oxidation products observed in the Fenton-like system Cu(II)/H2O2/reductant in nucleoside and oligodeoxynucleotide contexts

1 reference

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Factors that influence telomeric oxidative base damage and repair by DNA glycosylase OGG1

1 reference

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Sizing the ends: normal length of human telomeres

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G-Quadruplex DNA Sequences Are Evolutionarily Conserved and Associated with Distinct Genomic Features in Saccharomyces cerevisiae

1 reference

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Structural insights into G-quadruplexes: towards new anticancer drugs

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Oxidatively generated base damage to cellular DNA.

1 reference

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Telomeres: protecting chromosomes against genome instability

1 reference

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6 June 2018

Mutation versus repair: NEIL1 removal of hydantoin lesions in single-stranded, bulge, bubble, and duplex DNA contexts

1 reference

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A comprehensive catalogue of somatic mutations from a human cancer genome

1 reference

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Influence of substrate complexity on the diastereoselective formation of spiroiminodihydantoin and guanidinohydantoin from chromate oxidation

1 reference

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6 June 2018

How telomeres solve the end-protection problem

1 reference

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6 June 2018

Iminohydantoin lesion induced in DNA by peracids and other epoxidizing oxidants.

1 reference

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6 June 2018

Analysis of 7,8-dihydro-8-oxo-2'-deoxyguanosine in cellular DNA during oxidative stress

1 reference

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Mutational spectra of human cancer.

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6 June 2018

Stability and kinetics of G-quadruplex structures

1 reference

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6 June 2018

Oxidatively generated damage to the guanine moiety of DNA: mechanistic aspects and formation in cells

1 reference

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6 June 2018

Superior removal of hydantoin lesions relative to other oxidized bases by the human DNA glycosylase hNEIL1

1 reference

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1 reference

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6 June 2018

Structures, folding patterns, and functions of intramolecular DNA G-quadruplexes found in eukaryotic promoter regions

1 reference

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Oxidation of single-stranded oligonucleotides by carbonate radical anions: generating intrastrand cross-links between guanine and thymine bases separated by cytosines

1 reference

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DNA-protein cross-links between guanine and lysine depend on the mechanism of oxidation for formation of C5 vs C8 guanosine adducts

1 reference

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6 June 2018

Human telomere, oncogenic promoter and 5'-UTR G-quadruplexes: diverse higher order DNA and RNA targets for cancer therapeutics

1 reference

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6 June 2018

Structure of two intramolecular G-quadruplexes formed by natural human telomere sequences in K+ solution

1 reference

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6 June 2018

Base-excision repair of oxidative DNA damage

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6 June 2018

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6 June 2018

Mechanisms of oxidation of guanine in DNA by carbonate radical anion, a decomposition product of nitrosoperoxycarbonate

1 reference

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Different loop arrangements of intramolecular human telomeric (3+1) G-quadruplexes in K+ solution

1 reference

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1 reference

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6 June 2018

Structure of the human telomere in K+ solution: an intramolecular (3 + 1) G-quadruplex scaffold

1 reference

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6 June 2018

Human telomeric sequence forms a hybrid-type intramolecular G-quadruplex structure with mixed parallel/antiparallel strands in potassium solution

1 reference

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Telomere end-binding proteins control the formation of G-quadruplex DNA structures in vivo

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Highly prevalent putative quadruplex sequence motifs in human DNA

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1 reference

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Oxidative DNA damage associated with combination of guanine and superoxide radicals and repair mechanisms via radical trapping

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6 June 2018

Crystal structure of parallel quadruplexes from human telomeric DNA

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6 June 2018

Site-specific probing of oxidative reactivity and telomerase function using 7,8-dihydro-8-oxoguanine in telomeric DNA.

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6 June 2018

Direct oxidation of guanine and 7,8-dihydro-8-oxoguanine in DNA by a high-valent chromium complex: a possible mechanism for chromate genotoxicity

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6 June 2018

The carbonate radical is a site-selective oxidizing agent of guanine in double-stranded oligonucleotides

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6 June 2018

Site-specific DNA damage at the GGG sequence by UVA involves acceleration of telomere shortening

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6 June 2018

Nitrogen dioxide as an oxidizing agent of 8-oxo-7,8-dihydro-2'-deoxyguanosine but not of 2'-deoxyguanosine

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6 June 2018

Peroxynitrite-induced secondary oxidative lesions at guanine nucleobases: chemical stability and recognition by the Fpg DNA repair enzyme

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6 June 2018

In vitro DNA synthesis opposite oxazolone and repair of this DNA damage using modified oligonucleotides

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6 June 2018

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Ionization-reactivity relationships for cysteine thiols in polypeptides.

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6 June 2018

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6 June 2018

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6 June 2018

Singlet oxygen induces predominantly G to T transversions on a single-stranded shuttle vector replicated in monkey cells.

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6 June 2018

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6 June 2018

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6 June 2018

A new method for sequencing DNA

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6 June 2018

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18 August 2018

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18 August 2018

The tail of the telomere

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18 August 2018

Telomerase recruitment by the telomere end binding protein-beta facilitates G-quadruplex DNA unfolding in ciliates.

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18 August 2018

Oxidation of guanine and 8-oxo-7,8-dihydroguanine by carbonate radical anions: insight from oxygen-18 labeling experiments

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18 August 2018

Duplex and quadruplex DNA binding and photocleavage by trioxatriangulenium ion.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3720687

18 August 2018

Spiroiminodihydantoin and guanidinohydantoin are the dominant products of 8-oxoguanosine oxidation at low fluxes of peroxynitrite: mechanistic studies with 18O.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3720687

18 August 2018

Charge transport in DNA duplex/quadruplex conjugates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3720687

18 August 2018

The hydantoin lesions formed from oxidation of 7,8-dihydro-8-oxoguanine are potent sources of replication errors in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3720687

18 August 2018

Oxidative charge transport through DNA in nucleosome core particles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3720687

18 August 2018

Charge migration in DNA: ion-gated transport

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3720687

18 August 2018

Formation of spiroiminodihydantoin nucleoside by reaction of 8-oxo-7,8-dihydro-2'-deoxyguanosine with hypochlorous acid or a myeloperoxidase-H(2)O(2)-Cl(-) system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3720687

18 August 2018

Characterization of hydantoin products from one-electron oxidation of 8-oxo-7,8-dihydroguanosine in a nucleoside model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3720687

18 August 2018

Topological Characterization of Nucleic Acid G-Quadruplexes by UV Absorption and Circular Dichroism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3720687

2 December 2018

Quantitation of 8-Oxoguanine and Strand Breaks Produced by Four Oxidizing Agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3720687

2 December 2018

Guanine oxidation: one- and two-electron reactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/23438298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative damage generated by an oxo-metalloporphyrin onto the human telomeric sequence

1 reference

https://pubmed.ncbi.nlm.nih.gov/23438298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Base modification and strand breakage in isolated calf thymus DNA and in DNA from human skin epidermal keratinocytes exposed to peroxynitrite or 3-morpholinosydnonimine

1 reference

https://pubmed.ncbi.nlm.nih.gov/23438298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-distance radical cation transport in DNA: Horizontal charge hopping in a dimeric quadruplex

1 reference

https://pubmed.ncbi.nlm.nih.gov/23438298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of spiroiminodihydantoin as a product of one-electron oxidation of 8-Oxo-7,8-dihydroguanosine

1 reference

https://pubmed.ncbi.nlm.nih.gov/23438298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The pH-dependent role of superoxide in riboflavin-catalyzed photooxidation of 8-oxo-7,8-dihydroguanosine

1 reference

https://pubmed.ncbi.nlm.nih.gov/23438298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modification of DNA bases by photosensitized one-electron oxidation

1 reference

https://pubmed.ncbi.nlm.nih.gov/23438298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The new models of the human telomere d[AGGG(TTAGGG)3] in K+ solution

1 reference

https://pubmed.ncbi.nlm.nih.gov/23438298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative Nucleobase Modifications Leading to Strand Scission

1 reference

https://pubmed.ncbi.nlm.nih.gov/23438298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Steric effects on water accessability control sequence-selectivity of radical cation reactions in DNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/23438298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A Metal-Mediated Conformational Switch Controls G-Quadruplex Binding Affinity

1 reference

https://pubmed.ncbi.nlm.nih.gov/23438298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hydration is a major determinant of the G-quadruplex stability and conformation of the human telomere 3' sequence of d(AG3(TTAG3)3)

1 reference

https://pubmed.ncbi.nlm.nih.gov/23438298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Site-specific DNA damage at GGG sequence by oxidative stress may accelerate telomere shortening

1 reference

https://pubmed.ncbi.nlm.nih.gov/23438298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1021/TX400028Y

1 reference

Europe PubMed Central

PMC publication ID

9 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

9 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

9 October 2017

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