(Q41810950)

English

TLR2 and TLR4 signaling pathways are required for recombinant Brucella abortus BCSP31-induced cytokine production, functional upregulation of mouse macrophages, and the Th1 immune response in vivo and in vitro

scientific article published on 28 April 2014

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

12 October 2017

TLR2 and TLR4 signaling pathways are required for recombinant Brucella abortus BCSP31-induced cytokine production, functional upregulation of mouse macrophages, and the Th1 immune response in vivo and in vitro (English)

1 reference

Europe PubMed Central

PMC publication ID

12 October 2017

toll-like receptor

0 references

Brucella abortus

1 reference

based on heuristic

inferred from title

author name string

Jia-Yun Li

1

1 reference

Europe PubMed Central

PMC publication ID

12 October 2017

Yuan Liu

2

1 reference

Europe PubMed Central

PMC publication ID

12 October 2017

Xiao-Xue Gao

3

1 reference

Europe PubMed Central

PMC publication ID

12 October 2017

Xiang Gao

4

1 reference

Europe PubMed Central

PMC publication ID

12 October 2017

Hong Cai

5

1 reference

Europe PubMed Central

PMC publication ID

12 October 2017

publication date

28 April 2014

1 reference

Europe PubMed Central

PMC publication ID

12 October 2017

Cellular and Molecular Immunology

1 reference

Europe PubMed Central

PMC publication ID

12 October 2017

11

1 reference

Europe PubMed Central

PMC publication ID

12 October 2017

5

1 reference

Europe PubMed Central

PMC publication ID

12 October 2017

477-494

1 reference

Europe PubMed Central

PMC publication ID

12 October 2017

ATF4 is directly recruited by TLR4 signaling and positively regulates TLR4-trigged cytokine production in human monocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197203

6 June 2018

The role of innate immune signals in immunity to Brucella abortus

1 reference

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6 June 2018

Toll-like receptors are critical for clearance of Brucella and play different roles in development of adaptive immunity following aerosol challenge in mice

1 reference

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6 June 2018

TLR2 signaling subpathways regulate TLR9 signaling for the effective induction of IL-12 upon stimulation by heat-killed Brucella abortus

1 reference

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6 June 2018

Recombinant MPT83 derived from Mycobacterium tuberculosis induces cytokine production and upregulates the function of mouse macrophages through TLR2.

1 reference

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6 June 2018

Interleukin-1 receptor-associated kinase 4 is essential for initial host control of Brucella abortus infection

1 reference

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6 June 2018

MyD88 and STING signaling pathways are required for IRF3-mediated IFN-β induction in response to Brucella abortus infection

1 reference

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6 June 2018

Toll-like receptors and their crosstalk with other innate receptors in infection and immunity

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6 June 2018

An oral vaccine based on U-Omp19 induces protection against B. abortus mucosal challenge by inducing an adaptive IL-17 immune response in mice

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6 June 2018

Cell-mediated immunity in human brucellosis.

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6 June 2018

Pulsatile stimulation determines timing and specificity of NF-kappaB-dependent transcription

1 reference

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6 June 2018

Evidence of Brucella abortus OPS dictating uptake and restricting NF-kappaB activation in murine macrophages.

1 reference

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6 June 2018

Roles for TAB1 in regulating the IL-1-dependent phosphorylation of the TAB3 regulatory subunit and activity of the TAK1 complex

1 reference

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6 June 2018

Brucella abortus uses a stealthy strategy to avoid activation of the innate immune system during the onset of infection

1 reference

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6 June 2018

Identification of proteins expressed at extremely low level in Arabidopsis leaves

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6 June 2018

Ubiquitin-mediated activation of TAK1 and IKK.

1 reference

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6 June 2018

The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling

1 reference

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6 June 2018

Cooperation of Toll-like receptor signals in innate immune defence

1 reference

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6 June 2018

TGF-beta activated kinase-1: new insights into the diverse roles of TAK1 in development and immunity

1 reference

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6 June 2018

Toll-like receptor function and signaling

1 reference

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6 June 2018

1 reference

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6 June 2018

Nuclear factor-kappaB activation: a question of life or death

1 reference

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6 June 2018

Ubiquitin signalling in the NF-kappaB pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197203

6 June 2018

Human brucellosis in a nonendemic country: a report from Germany, 2002 and 2003.

1 reference

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6 June 2018

LPS, TLR4 and infectious disease diversity.

1 reference

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6 June 2018

Toll-like receptor control of the adaptive immune responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197203

6 June 2018

Lipoproteins, not lipopolysaccharide, are the key mediators of the proinflammatory response elicited by heat-killed Brucella abortus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197203

6 June 2018

Toll-like receptor signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197203

6 June 2018

Mitogen-activated protein kinases in apoptosis regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197203

6 June 2018

Role of Toll-like receptor 4 in induction of cell-mediated immunity and resistance to Brucella abortus infection in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197203

6 June 2018

Leucine-rich repeats and pathogen recognition in Toll-like receptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197203

6 June 2018

Toll-like receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197203

6 June 2018

Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197203

6 June 2018

Piceatannol inhibits TNF-induced NF-kappaB activation and NF-kappaB-mediated gene expression through suppression of IkappaBalpha kinase and p65 phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197203

6 June 2018

The innate immune response against Brucella in humans.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197203

6 June 2018

Toll-like receptor 4 (TLR4)-deficient murine macrophage cell line as an in vitro assay system to show TLR4-independent signaling of Bacteroides fragilis lipopolysaccharide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197203

6 June 2018

IRAK-4: a novel member of the IRAK family with the properties of an IRAK-kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197203

6 June 2018

Innate immune recognition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197203

6 June 2018

Duration of nuclear NF-kappaB action regulated by reversible acetylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197203

6 June 2018

Methotrexate suppresses NF-kappaB activation through inhibition of IkappaBalpha phosphorylation and degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197203

6 June 2018

Targets of glucocorticoid action on TNF-alpha release by macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197203

6 June 2018

Immunity and protection against Brucella abortus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197203

6 June 2018

Signaling by toll-like receptor 2 and 4 agonists results in differential gene expression in murine macrophages.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197203

6 June 2018

Toll-like receptors in the induction of the innate immune response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197203

6 June 2018

The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197203

6 June 2018

The nuclear factor-kappaB engages CBP/p300 and histone acetyltransferase activity for transcriptional activation of the interleukin-6 gene promoter.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197203

6 June 2018

IkappaB kinases phosphorylate NF-kappaB p65 subunit on serine 536 in the transactivation domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197203

6 June 2018

Inhibition of interleukin-1-stimulated NF-kappaB RelA/p65 phosphorylation by mesalamine is accompanied by decreased transcriptional activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197203

6 June 2018

Cutting edge: inflammatory signaling by Borrelia burgdorferi lipoproteins is mediated by toll-like receptor 2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197203

6 June 2018

Cell activation and apoptosis by bacterial lipoproteins through toll-like receptor-2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197203

6 June 2018

Host defense mechanisms triggered by microbial lipoproteins through toll-like receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197203

6 June 2018

MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197203

6 June 2018

NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197203

6 June 2018

NF-kappa B as a frequent target for immunosuppressive and anti-inflammatory molecules.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197203

6 June 2018

Brucella abortus as a potential vaccine candidate: induction of interleukin-12 secretion and enhanced B7.1 and B7.2 and intercellular adhesion molecule 1 surface expression in elutriated human monocytes stimulated by heat-inactivated B. abortus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197203

6 June 2018

The NF-kappa B and I kappa B proteins: new discoveries and insights

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197203

6 June 2018

Oral immunization of mice and swine with an attenuated Salmonella choleraesuis [delta cya-12 delta(crp-cdt)19] mutant containing a recombinant plasmid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197203

6 June 2018

Endogenous gamma interferon mediates resistance to Brucella abortus infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197203

6 June 2018

A protein kinase involved in the regulation of inflammatory cytokine biosynthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197203

6 June 2018

Differential induction of macrophage-derived cytokines by live and dead intracellular bacteria in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197203

6 June 2018

Rel/NF-kappa B/I kappa B family: intimate tales of association and dissociation

1 reference

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6 June 2018

Regulation of interleukin 12 p40 expression through an NF-kappa B half-site

1 reference

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6 June 2018

Oral immunization of mice with attenuated Salmonella typhimurium containing a recombinant plasmid which codes for production of a 31-kilodalton protein of Brucella abortus

1 reference

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6 June 2018

Swine immunity to an attenuated Salmonella typhimurium mutant containing a recombinant plasmid which codes for production of a 31-kilodalton protein of Brucella abortus

1 reference

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6 June 2018

Brucella lipoproteins mimic dendritic cell maturation induced by Brucella abortus

1 reference

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18 August 2018

A combined DNA vaccine enhances protective immunity against Mycobacterium tuberculosis and Brucella abortus in the presence of an IL-12 expression vector

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18 August 2018

A combined DNA vaccine encoding BCSP31, SOD, and L7/L12 confers high protection against Brucella abortus 2308 by inducing specific CTL responses.

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18 August 2018

A bile salt hydrolase of Brucella abortus contributes to the establishment of a successful infection through the oral route in mice

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18 August 2018

Essential function for the kinase TAK1 in innate and adaptive immune responses.

1 reference

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18 August 2018

MyD88, but not toll-like receptors 4 and 2, is required for efficient clearance of Brucella abortus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197203

18 August 2018

Heat-killed Brucella abortus induces TNF and IL-12p40 by distinct MyD88-dependent pathways: TNF, unlike IL-12p40 secretion, is Toll-like receptor 2 dependent

1 reference

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18 August 2018

Distinct roles of the Ikappa B kinase alpha and beta subunits in liberating nuclear factor kappa B (NF-kappa B) from Ikappa B and in phosphorylating the p65 subunit of NF-kappa B.

1 reference

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18 August 2018

Possible new role for NF-kappaB in the resolution of inflammation.

1 reference

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18 August 2018

Mycobacteria-induced TNF-alpha and IL-10 formation by human macrophages is differentially regulated at the level of mitogen-activated protein kinase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4197203

18 August 2018

Interferon-gamma is crucial for surviving a Brucella abortus infection in both resistant C57BL/6 and susceptible BALB/c mice.

1 reference

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18 August 2018

Role of NFkappaB in antigen presentation and development of regulatory T cells elucidated by treatment of dendritic cells with the proteasome inhibitor PSI.

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18 August 2018

Toll-like receptor 2 functions as a pattern recognition receptor for diverse bacterial products.

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18 August 2018

Cytokine production in the murine response to brucella infection or immunization with antigenic extracts.

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18 August 2018

Genomic stability of genotyping markers in Chlamydia trachomatis

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21 January 2018

Cutting edge: histone acetylation and recombination at the TCR gamma locus follows IL-7 induction.

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21 January 2018

The Protein Moiety of Brucella abortus Outer Membrane Protein 16 Is a New Bacterial Pathogen-Associated Molecular Pattern That Activates Dendritic Cells In Vivo, Induces a Th1 Immune Response, and Is a Promising Self-Adjuvanting Vaccine against Syste

1 reference

https://api.crossref.org/works/10.1038%2FCMI.2014.28

21 January 2018

MyD88-Dependent Activation of B220-CD11b+LY-6C+ Dendritic Cells during Brucella melitensis Infection

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https://api.crossref.org/works/10.1038%2FCMI.2014.28

21 January 2018

Pathogenesis and cellular immunity in experimental murine brucellosis

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunogenicity of Brucella abortus salt-extractable proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/24769793

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunogenicity of Brucella-extracted and recombinant protein vaccines in CD-1 and BALB/c mice

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https://pubmed.ncbi.nlm.nih.gov/24769793

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of a p38 mitogen-activated protein kinase in human neutrophils by lipopolysaccharide

1 reference

https://pubmed.ncbi.nlm.nih.gov/24769793

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Changes in the strength of co-stimulation through the B7/CD28 pathway alter functional T cell responses to altered peptide ligands

1 reference

https://pubmed.ncbi.nlm.nih.gov/24769793

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-2 expression by a subpopulation of primary T cells is linked to enhanced memory/effector function

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https://pubmed.ncbi.nlm.nih.gov/24769793

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Central role of MyD88-dependent dendritic cell maturation and proinflammatory cytokine production to control Brucella abortus infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/24769793

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toll-like receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/24769793

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-12 Induction by a Th1-Inducing Adjuvant In Vivo: Dendritic Cell Subsets and Regulation by IL-10

1 reference

https://pubmed.ncbi.nlm.nih.gov/24769793

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fundamentals of host immune response against Brucella abortus: what the mouse model has revealed about control of infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/24769793

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distinct dendritic cell populations sequentially present antigen to CD4 T cells and stimulate different aspects of cell-mediated immunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/24769793

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/CMI.2014.28

1 reference

Europe PubMed Central

PMC publication ID

12 October 2017

Dimensions Publication ID

0 references

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 October 2017

ResearchGate publication ID

0 references

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