(Q41811106)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27226027%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

title

Endoplasmic reticulum stress enhances fibrosis through IRE1α-mediated degradation of miR-150 and XBP-1 splicing (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27226027%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

main subject

endoplasmic reticulum

0 references

author

Krista Rombouts

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27226027%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Joey Lau

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27226027%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Johan Kreuger

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27226027%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Pär Gerwins

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27226027%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

1

Femke Heindryckx

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27226027%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

author name string

François Binet

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27226027%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Markella Ponticos

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27226027%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

publication date

1 July 2016

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27226027%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

published in

EMBO Molecular Medicine

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27226027%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

volume

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27226027%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

issue

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27226027%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

page(s)

729-744

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27226027%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

2 April 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4931288/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Pathologic Regulation of Collagen I by an Aberrant Protein Phosphatase 2A/Histone Deacetylase C4/MicroRNA-29 Signal Axis in Idiopathic Pulmonary Fibrosis Fibroblasts

6 June 2018

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A decrease in miR-150 regulates the malignancy of pancreatic cancer by targeting c-Myb and MUC4.

6 June 2018

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Failed degradation of JunB contributes to overproduction of type I collagen and development of dermal fibrosis in patients with systemic sclerosis

6 June 2018

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miR-150 functions as a tumour suppressor in human colorectal cancer by targeting c-Myb

6 June 2018

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6 June 2018

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New Insights into the Pathogenesis of Alcohol-Induced ER Stress and Liver Diseases

6 June 2018

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Mechanisms that mediate the development of fibrosis in patients with Crohn's disease

6 June 2018

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Endoplasmic reticulum stress contributes to aortic stiffening via proapoptotic and fibrotic signaling mechanisms

6 June 2018

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SIRT7 represses Myc activity to suppress ER stress and prevent fatty liver disease

6 June 2018

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Understanding the origin, activation and regulation of matrix-producing myofibroblasts for treatment of fibrotic disease.

6 June 2018

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Stressed to death - mechanisms of ER stress-induced cell death.

6 June 2018

1 reference

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Scleroderma pathogenesis: a pivotal role for fibroblasts as effector cells

6 June 2018

1 reference

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MicroRNAs inhibit the translation of target mRNAs on the endoplasmic reticulum in Arabidopsis

6 June 2018

1 reference

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Molecular basis of selective atrial fibrosis due to overexpression of transforming growth factor-β1.

6 June 2018

1 reference

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Activation of hepatic stellate cells is suppressed by microRNA-150.

6 June 2018

1 reference

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The rough endoplasmatic reticulum is a central nucleation site of siRNA-mediated RNA silencing

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4931288

The unfolded protein response and chemical chaperones reduce protein misfolding and colitis in mice

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4931288

Endoplasmic reticulum stress as a pro-fibrotic stimulus

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4931288

MicroRNAs, transforming growth factor beta-1, and tissue fibrosis.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4931288

IRE1α cleaves select microRNAs during ER stress to derepress translation of proapoptotic Caspase-2.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4931288

IRE1α induces thioredoxin-interacting protein to activate the NLRP3 inflammasome and promote programmed cell death under irremediable ER stress.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4931288

Oxidative Stress and the ER Stress Response in a Murine Model for Early-Stage Alcoholic Liver Disease

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4931288

The molecular basis for selective inhibition of unconventional mRNA splicing by an IRE1-binding small molecule

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4931288

Emerging evidence for endoplasmic reticulum stress in the pathogenesis of idiopathic pulmonary fibrosis

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4931288

MCPIP1 ribonuclease antagonizes dicer and terminates microRNA biogenesis through precursor microRNA degradation

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4931288

Involvement of endoplasmic reticulum stress in inflammatory bowel disease: a different implication for colonic and ileal disease?

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4931288

Endoplasmic reticulum stress implicated in the development of renal fibrosis

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4931288

Involvement of endoplasmic reticulum stress in myofibroblastic differentiation of lung fibroblasts.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4931288

Seven steps to stellate cells

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4931288

Fibroblasts and myofibroblasts: what are we talking about?

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4931288

Endoplasmic reticulum stress in liver disease

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4931288

Characterization of the TRBP domain required for dicer interaction and function in RNA interference

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4931288

ATF6alpha induces XBP1-independent expansion of the endoplasmic reticulum

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4931288

c-Myb is an evolutionary conserved miR-150 target and miR-150/c-Myb interaction is important for embryonic development

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4931288

Regulation of hepatic lipogenesis by the transcription factor XBP1

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4931288

Fibroblast differentiation in wound healing and fibrosis

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4931288

Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4931288

Transformation-associated gene regulation by ATF6alpha during hepatocarcinogenesis

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4931288

XBP-1 is required for biogenesis of cellular secretory machinery of exocrine glands

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4931288

ER stress and the unfolded protein response

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4931288

XBP1: a link between the unfolded protein response, lipid biosynthesis, and biogenesis of the endoplasmic reticulum.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4931288

TGF-beta signaling and the fibrotic response

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4931288

Prediction of mammalian microRNA targets

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4931288

IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4931288

Plasma cell differentiation requires the transcription factor XBP-1

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4931288

The endoribonuclease activity of mammalian IRE1 autoregulates its mRNA and is required for the unfolded protein response

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4931288

c-Myb modulates transcription of the alpha-smooth muscle actin gene in activated hepatic stellate cells

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4931288

Adenovector-mediated gene transfer of active transforming growth factor-beta1 induces prolonged severe fibrosis in rat lung

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4931288

An algorithm for the grading of activity in chronic hepatitis C. The METAVIR Cooperative Study Group

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4931288

Neuronal ER stress impedes myeloid-cell-induced vascular regeneration through IRE1α degradation of netrin-1.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4931288

miR-150 down-regulation contributes to the constitutive type I collagen overexpression in scleroderma dermal fibroblasts via the induction of integrin β3.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4931288

MARCKS actin-binding capacity mediates actin filament assembly during mitosis in human hepatic stellate cells.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4931288

Inhibition of placental growth factor activity reduces the severity of fibrosis, inflammation, and portal hypertension in cirrhotic mice.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4931288

Comparison of three research models of portal hypertension in mice: macroscopic, histological and portal pressure evaluation

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4931288

TGF-beta1 in liver fibrosis: an inducible transgenic mouse model to study liver fibrogenesis

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4931288

Further Pharmacological and Genetic Evidence for the Efficacy of PlGF Inhibition in Cancer and Eye Disease

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4931288

ATF6 is a transcription factor specializing in the regulation of quality control proteins in the endoplasmic reticulum

2 December 2018

1 reference

12 December 2020

Differential contributions of ATF6 and XBP1 to the activation of endoplasmic reticulum stress-responsive cis-acting elements ERSE, UPRE and ERSE-II

1 reference

12 December 2020

Quantification of histochemical staining by color deconvolution

1 reference

12 December 2020

Hepatic expression of c-Myb in chronic human liver disease

1 reference

12 December 2020

Identifiers

DOI

10.15252/EMMM.201505925

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27226027%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27226027%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

1 reference