(Q41824788)

English

Cardiac energy dependence on glucose increases metabolites related to glutathione and activates metabolic genes controlled by mechanistic target of rapamycin.

scientific article published on 24 February 2015

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scholarly article

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1 March 2020

Cardiac energy dependence on glucose increases metabolites related to glutathione and activates metabolic genes controlled by mechanistic target of rapamycin (English)

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1 March 2020

Jonathan Schisler

1

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1 March 2020

Trisha J Grevengoed

2

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1 March 2020

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1 March 2020

9

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1 March 2020

author name string

Florencia Pascual

3

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1 March 2020

Daniel E Cooper

4

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1 March 2020

Jessica M Ellis

5

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1 March 2020

David S Paul

6

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1 March 2020

Cam Patterson

8

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1 March 2020

Rosalind A Coleman

10

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1 March 2020

publication date

24 February 2015

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1 March 2020

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease

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1 March 2020

4

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1 March 2020

2

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1 March 2020

Translocation of glycogen synthase kinase-3β (GSK-3β), a trigger of permeability transition, is kinase activity-dependent and mediated by interaction with voltage-dependent anion channel 2 (VDAC2).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4345858

6 June 2018

Deficiency of cardiac Acyl-CoA synthetase-1 induces diastolic dysfunction, but pathologic hypertrophy is reversed by rapamycin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4345858

6 June 2018

Inducible overexpression of GLUT1 prevents mitochondrial dysfunction and attenuates structural remodeling in pressure overload but does not prevent left ventricular dysfunction.

1 reference

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6 June 2018

A growing role for mTOR in promoting anabolic metabolism

1 reference

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6 June 2018

Glucose regulation of load-induced mTOR signaling and ER stress in mammalian heart

1 reference

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6 June 2018

Nutrient signaling to mTOR and cell growth

1 reference

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A practical guide to metabolomic profiling as a discovery tool for human heart disease

1 reference

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Growth differentiation factor 15 stimulates rapamycin-sensitive ovarian cancer cell growth and invasion

1 reference

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Hypoxia induces PDK4 gene expression through induction of the orphan nuclear receptor ERRγ

1 reference

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6 June 2018

Role of TRIB3 in regulation of insulin sensitivity and nutrient metabolism during short-term fasting and nutrient excess

1 reference

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6 June 2018

MetaboAnalyst 2.0--a comprehensive server for metabolomic data analysis

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mTOR signaling in growth control and disease

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Waterborne manganese exposure alters plasma, brain, and liver metabolites accompanied by changes in stereotypic behaviors

1 reference

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Profiling CCK-mediated pancreatic growth: the dynamic genetic program and the role of STATs as potential regulators

1 reference

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Web-based inference of biological patterns, functions and pathways from metabolomic data using MetaboAnalyst

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Serum and urine metabolite profiling reveals potential biomarkers of human hepatocellular carcinoma

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Three 4-letter words of hypertension-related cardiac hypertrophy: TRPC, mTOR, and HDAC.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4345858

6 June 2018

Mouse cardiac acyl coenzyme a synthetase 1 deficiency impairs Fatty Acid oxidation and induces cardiac hypertrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4345858

6 June 2018

mTOR: from growth signal integration to cancer, diabetes and ageing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4345858

6 June 2018

Activation of a metabolic gene regulatory network downstream of mTOR complex 1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4345858

6 June 2018

Gene expression and integrated stress response in HepG2/C3A cells cultured in amino acid deficient medium

1 reference

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6 June 2018

Metabolic therapy at the crossroad: how to optimize myocardial substrate utilization?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4345858

6 June 2018

Metabolic toxicity of the heart: insights from molecular imaging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4345858

6 June 2018

Mammalian target of rapamycin is a critical regulator of cardiac hypertrophy in spontaneously hypertensive rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4345858

6 June 2018

Liver-specific loss of long chain acyl-CoA synthetase-1 decreases triacylglycerol synthesis and beta-oxidation and alters phospholipid fatty acid composition

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6 June 2018

Increased glucose uptake and oxidation in mouse hearts prevent high fatty acid oxidation but cause cardiac dysfunction in diet-induced obesity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4345858

6 June 2018

MetaboAnalyst: a web server for metabolomic data analysis and interpretation

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6 June 2018

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

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Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

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6 June 2018

Insulin stimulation of gamma-glutamylcysteine ligase catalytic subunit expression increases endothelial GSH during oxidative stress: influence of low glucose

1 reference

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6 June 2018

Metabolite profiling of blood from individuals undergoing planned myocardial infarction reveals early markers of myocardial injury

1 reference

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6 June 2018

Mechanisms and methods in glucose metabolism and cell death

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6 June 2018

The DAVID Gene Functional Classification Tool: a novel biological module-centric algorithm to functionally analyze large gene lists

1 reference

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6 June 2018

Glucose phosphorylation is required for insulin-dependent mTOR signalling in the heart

1 reference

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CHOP (C/EBP homologous protein) and ASNS (asparagine synthetase) induction in cybrid cells harboring MELAS and NARP mitochondrial DNA mutations

1 reference

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PI3K, RSK, and mTOR signal networks for the GST gene regulation

1 reference

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1 reference

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1 reference

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1 reference

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6 June 2018

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1 reference

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1 reference

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6 June 2018

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1 reference

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Chronic ethanol consumption alters mammalian gastrointestinal content metabolites.

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1 reference

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1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Universal mouse reference RNA derived from neonatal mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/25713290

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of energy metabolism of the heart during acute increase in heart work

1 reference

https://pubmed.ncbi.nlm.nih.gov/25713290

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-Term Effects of Increased Glucose Entry on Mouse Hearts During Normal Aging and Ischemic Stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/25713290

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1161/JAHA.114.001136

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25713290%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25713290%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25713290%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

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