(Q41848433)

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The centrosomal adaptor TACC3 and the microtubule polymerase chTOG interact via defined C-terminal subdomains in an Aurora-A kinase-independent manner.

scientific article published on 22 November 2013

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1 March 2020

The centrosomal adaptor TACC3 and the microtubule polymerase chTOG interact via defined C-terminal subdomains in an Aurora-A kinase-independent manner (English)

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André Abts

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Journal of Biological Chemistry

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1 March 2020

A small compound targeting TACC3 revealed its different spatiotemporal contributions for spindle assembly in cancer cells

1 reference

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5 June 2018

Self-assembly and sorting of acentrosomal microtubules by TACC3 facilitate kinetochore capture during the mitotic spindle assembly.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879581

5 June 2018

Coordination of adjacent domains mediates TACC3-ch-TOG-clathrin assembly and mitotic spindle binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879581

5 June 2018

Aurora A kinase and its substrate TACC3 are required for central spindle assembly

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879581

5 June 2018

Role of centrosomal adaptor proteins of the TACC family in the regulation of microtubule dynamics during mitotic cell division

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879581

5 June 2018

Regulating the ARNT/TACC3 Axis: Multiple Approaches to Manipulating Protein/Protein Interactions with Small Molecules

1 reference

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5 June 2018

SH3-mediated targeting of Wrch1/RhoU by multiple adaptor proteins

1 reference

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5 June 2018

Oncogenic FGFR3 gene fusions in bladder cancer

1 reference

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Centrosomes, chromosome instability (CIN) and aneuploidy

1 reference

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5 June 2018

GF-15, a novel inhibitor of centrosomal clustering, suppresses tumor cell growth in vitro and in vivo

1 reference

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5 June 2018

DOCK7 interacts with TACC3 to regulate interkinetic nuclear migration and cortical neurogenesis

1 reference

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5 June 2018

Transforming fusions of FGFR and TACC genes in human glioblastoma

1 reference

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5 June 2018

A landscape of driver mutations in melanoma

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5 June 2018

Abnormal SDS-PAGE migration of cytosolic proteins can identify domains and mechanisms that control surfactant binding

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5 June 2018

Losing balance: the origin and impact of aneuploidy in cancer

1 reference

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5 June 2018

Breaking the ties that bind: new advances in centrosome biology.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879581

5 June 2018

Centrosome amplification in tumorigenesis

1 reference

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5 June 2018

The role of clathrin in mitotic spindle organisation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879581

5 June 2018

The centrosome in cells and organisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879581

5 June 2018

A clinical overview of centrosome amplification in human cancers

1 reference

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5 June 2018

The centrosome cycle: Centriole biogenesis, duplication and inherent asymmetries

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879581

5 June 2018

Pulling it together: The mitotic function of TACC3.

1 reference

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5 June 2018

Novel functions of endocytic player clathrin in mitosis

1 reference

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5 June 2018

Centrosomes and cilia in human disease.

1 reference

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5 June 2018

Centrosome clustering and chromosomal (in)stability: a matter of life and death

1 reference

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5 June 2018

Coactivators necessary for transcriptional output of the hypoxia inducible factor, HIF, are directly recruited by ARNT PAS-B

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879581

5 June 2018

Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879581

5 June 2018

A TACC3/ch-TOG/clathrin complex stabilises kinetochore fibres by inter-microtubule bridging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879581

5 June 2018

Uncovering new substrates for Aurora A kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879581

5 June 2018

A critical role of integrin-linked kinase, ch-TOG and TACC3 in centrosome clustering in cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879581

5 June 2018

A small molecule accelerates neuronal differentiation in the adult rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879581

5 June 2018

Proteomic and functional analysis of the mitotic Drosophila centrosome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879581

5 June 2018

The centrosomal protein TACC3 controls paclitaxel sensitivity by modulating a premature senescence program

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879581

5 June 2018

Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes

1 reference

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5 June 2018

Systematic analysis of human protein complexes identifies chromosome segregation proteins

1 reference

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5 June 2018

Cdh1 controls the stability of TACC3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879581

5 June 2018

Centrosome function in cancer: guilty or innocent?

1 reference

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5 June 2018

From zero to many: control of centriole number in development and disease

1 reference

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5 June 2018

A BAR domain-mediated autoinhibitory mechanism for RhoGAPs of the GRAF family

1 reference

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5 June 2018

Mechanisms to suppress multipolar divisions in cancer cells with extra centrosomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879581

5 June 2018

The TACC proteins: TACC-ling microtubule dynamics and centrosome function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879581

5 June 2018

Centrosome amplification can initiate tumorigenesis in flies.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879581

5 June 2018

Xenopus TACC3/maskin is not required for microtubule stability but is required for anchoring microtubules at the centrosome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879581

5 June 2018

XMAP215 is a processive microtubule polymerase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879581

5 June 2018

Cep120 and TACCs control interkinetic nuclear migration and the neural progenitor pool.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879581

5 June 2018

The transforming acidic coiled coil 3 protein is essential for spindle-dependent chromosome alignment and mitotic survival

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879581

5 June 2018

TACC3 depletion sensitizes to paclitaxel-induced cell death and overrides p21WAF-mediated cell cycle arrest

1 reference

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5 June 2018

Phosphorylation of maskin by Aurora-A is regulated by RanGTP and importin beta

1 reference

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5 June 2018

TACC3 mediates the association of MBD2 with histone acetyltransferases and relieves transcriptional repression of methylated promoters

1 reference

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5 June 2018

Centrosomes in cellular regulation

1 reference

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5 June 2018

Aurora A activates D-TACC-Msps complexes exclusively at centrosomes to stabilize centrosomal microtubules

1 reference

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5 June 2018

Function and regulation of Maskin, a TACC family protein, in microtubule growth during mitosis

1 reference

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5 June 2018

Aberrations of TACC1 and TACC3 are associated with ovarian cancer

1 reference

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5 June 2018

Microtubule nucleation and anchoring at the centrosome are independent processes linked by ninein function

1 reference

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5 June 2018

A classic zinc finger from friend of GATA mediates an interaction with the coiled-coil of transforming acidic coiled-coil 3

1 reference

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5 June 2018

The centrosomal, putative tumor suppressor protein TACC2 is dispensable for normal development, and deficiency does not lead to cancer

1 reference

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5 June 2018

Structure-function evolution of the transforming acidic coiled coil genes revealed by analysis of phylogenetically diverse organisms

1 reference

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5 June 2018

Transforming acidic coiled-coil protein 3 (TACC3) controls friend of GATA-1 (FOG-1) subcellular localization and regulates the association between GATA-1 and FOG-1 during hematopoiesis

1 reference

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Interdependency of fission yeast Alp14/TOG and coiled coil protein Alp7 in microtubule localization and bipolar spindle formation

1 reference

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5 June 2018

TOGp, the human homolog of XMAP215/Dis1, is required for centrosome integrity, spindle pole organization, and bipolar spindle assembly

1 reference

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5 June 2018

Proteomic characterization of the human centrosome by protein correlation profiling

1 reference

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5 June 2018

TACC3 expression is tightly regulated during early differentiation

1 reference

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5 June 2018

The ch-TOG/XMAP215 protein is essential for spindle pole organization in human somatic cells

1 reference

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5 June 2018

Centrosomal TACCtics

1 reference

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5 June 2018

TACC3 expression and localization in the murine egg and ovary

1 reference

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5 June 2018

The centrosome cycle

1 reference

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5 June 2018

Centrosomes and cancer: lessons from a TACC.

1 reference

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5 June 2018

Interaction of the transforming acidic coiled-coil 1 (TACC1) protein with ch-TOG and GAS41/NuBI1 suggests multiple TACC1-containing protein complexes in human cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879581

5 June 2018

The centrosomal protein TACC3 is essential for hematopoietic stem cell function and genetically interfaces with p53-regulated apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879581

5 June 2018

XMAP215 regulates microtubule dynamics through two distinct domains.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879581

5 June 2018

The TACC domain identifies a family of centrosomal proteins that can interact with microtubules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879581

5 June 2018

Spindle assembly in animal cells.

1 reference

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5 June 2018

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

1 reference

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5 June 2018

Predicting coiled coils from protein sequences

1 reference

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5 June 2018

Never tear us apart--the importance of centrosome clustering.

1 reference

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18 August 2018

Disruption of Tacc3 function leads to in vivo tumor regression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879581

18 August 2018

The centrosome and mitotic spindle apparatus in cancer and senescence.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879581

18 August 2018

TACC3-TSC2 maintains nuclear envelope structure and controls cell division.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879581

18 August 2018

Aurora A phosphorylation of TACC3/maskin is required for centrosome-dependent microtubule assembly in mitosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879581

18 August 2018

Interaction of the transforming acidic coiled-coil 1 (TACC1) protein with ch-TOG and GAS41/NuBI1 suggests multiple TACC1-containing protein complexes in human cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.532333

21 January 2018

Localization of human TACC3 to mitotic spindles is mediated by phosphorylation on Ser558 by Aurora A: a novel pharmacodynamic method for measuring Aurora A activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/24273164

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TACC3 is required for the proper mitosis of sclerotome mesenchymal cells during formation of the axial skeleton

1 reference

https://pubmed.ncbi.nlm.nih.gov/24273164

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M113.532333

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24273164%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24273164%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24273164%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

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