(Q41863562)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23842210%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

title

Inferring multi-target QSAR models with taxonomy-based multi-task learning (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23842210%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23842210%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Frank M. Boeckler

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23842210%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

5

Andreas Zell

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23842210%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

author name string

Lars Rosenbaum

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23842210%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Alexander Dörr

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23842210%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

publication date

11 July 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23842210%20AND%20SRC:MED&resulttype=core&format=json

Journal of Cheminformatics

4 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23842210%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

volume

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23842210%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23842210%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

page(s)

33

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23842210%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 2.0 Generic

4 March 2020

copyright license

start time

11 July 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

1 reference

April 2022 Public Data File from Crossref

cites work

Comparability of mixed IC₅₀ data - a statistical analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104930

Prediction of compounds with closely related activity profiles using weighted support vector machine linear combinations

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104930

Small-molecule inhibitors binding to protein kinase. Part II: the novel pharmacophore approach of type II and type III inhibition

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104930

Significantly improved HIV inhibitor efficacy prediction employing proteochemometric models generated from antivirogram data

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104930

Dibenzosuberones as p38 mitogen-activated protein kinase inhibitors with low ATP competitiveness and outstanding whole blood activity

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104930

Multi-target drugs: the trend of drug research and development

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104930

The experimental uncertainty of heterogeneous public K(i) data.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104930

Rapid development of piperidine carboxamides as potent and selective anaplastic lymphoma kinase inhibitors

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104930

Tri- and tetrasubstituted pyrazole derivates: regioisomerism switches activity from p38MAP kinase to important cancer kinases.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104930

Next-generation sequencing for cancer diagnostics: a practical perspective.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104930

Reorganizing the protein space at the Universal Protein Resource (UniProt)

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104930

ChEMBL: a large-scale bioactivity database for drug discovery

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104930

From in silico target prediction to multi-target drug design: current databases, methods and applications

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104930

Interpreting linear support vector machine models with heat map molecule coloring

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104930

jCompoundMapper: An open source Java library and command-line tool for chemical fingerprints

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104930

Trust, but verify: on the importance of chemical structure curation in cheminformatics and QSAR modeling research

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104930

Systems approaches to polypharmacology and drug discovery

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104930

Extended-connectivity fingerprints

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104930

In-silico approaches to multi-target drug discovery : computer aided multi-target drug design, multi-target virtual screening

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104930

PIM serine/threonine kinases in the pathogenesis and therapy of hematologic malignancies and solid cancers

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104930

Structure of protein interaction networks and their implications on drug design

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104930

Targeted polypharmacology: discovery of dual inhibitors of tyrosine and phosphoinositide kinases

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104930

The future of high-throughput screening

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104930

A quantitative analysis of kinase inhibitor selectivity

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104930

Inhibitors of c-Jun N-terminal kinases: JuNK no more?

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104930

Rational design of inhibitors that bind to inactive kinase conformations

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104930

The efficiency of multi-target drugs: the network approach might help drug design

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104930

Combinatorial compound libraries for drug discovery: an ongoing challenge

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104930

The protein kinase complement of the human genome

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104930

Low affinity channel blocking (uncompetitive) NMDA receptor antagonists as therapeutic agents--toward an understanding of their favorable tolerability

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104930

Challenges in the design of multitarget drugs against multifactorial pathologies: a new life for medicinal chemistry?

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104930

Multiple weak hits confuse complex systems: a transcriptional regulatory network as an example

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104930

Metabolic network analysis of the causes and evolution of enzyme dispensability in yeast

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104930

Turning down, but not off.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4104930

The benefits of the multi-target approach in drug design and discovery

18 August 2018

1 reference

12 December 2020

Systematic identification of scaffolds representing compounds active against individual targets and single or multiple target families

1 reference

12 December 2020

A Free-Wilson-like Approach to Analyze QSAR Models Based on Graph Decomposition Kernels

1 reference

12 December 2020

Application of GQSAR for Scaffold Hopping and Lead Optimization in Multitarget Inhibitors

1 reference

12 December 2020

A Survey on Transfer Learning

1 reference

COCI

https://opencitations.net/index/coci/api/v1/references/10.1186/1758-2946-5-33

Proteochemometric modeling as a tool to design selective compounds and for extrapolating to novel targets

2 January 2022

1 reference

COCI

https://opencitations.net/index/coci/api/v1/references/10.1186/1758-2946-5-33

Efficient Training of Graph-Regularized Multitask SVMs

2 January 2022

1 reference

14 October 2024

https://opencitations.net/index/api/v1/references/10.1186/1758-2946-5-33

How to design multi-target drugs.

1 reference

14 October 2024

https://opencitations.net/index/api/v1/references/10.1186/1758-2946-5-33

Identifiers

DOI

10.1186/1758-2946-5-33

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23842210%20AND%20SRC:MED&resulttype=core&format=json

journals/jcheminf/RosenbaumDBBZ13

4 March 2020

DBLP publication ID

1 reference

DBLP Dataset 2021-01-02

Dimensions Publication ID

28 January 2021

1 reference

9 September 2019

https://scigraph.springernature.com/pub.10.1186/1758-2946-5-33

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23842210%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

PubMed publication ID

23842210

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23842210%20AND%20SRC:MED&resulttype=core&format=json