(Q41912806)

14 October 2017

Stability of peroxide antimalarials in the presence of human hemoglobin (English)

1 reference

14 October 2017

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1

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14 October 2017

Susan A Charman

7

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William N. Charman

object named as

William N Charman

3

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author name string

Eileen Ryan

2

1 reference

14 October 2017

Francis C K Chiu

4

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14 October 2017

Richard J Prankerd

5

1 reference

14 October 2017

Jonathan L Vennerstrom

6

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14 October 2017

language of work or name

English

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publication date

1 June 2009

1 reference

Antimicrobial Agents and Chemotherapy

14 October 2017

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14 October 2017

53

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14 October 2017

8

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14 October 2017

3496-3500

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Relationship between antimalarial activity and heme alkylation for spiro- and dispiro-1,2,4-trioxolane antimalarials

14 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715612

New developments in synthetic peroxidic drugs as artemisinin mimics

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715612

Artemisinin effectiveness in erythrocytes is reduced by heme and heme-containing proteins

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715612

Current perspectives on the mechanism of action of artemisinins

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715612

1.25 A resolution crystal structures of human haemoglobin in the oxy, deoxy and carbonmonoxy forms.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715612

The reaction of artemisinins with hemoglobin: a unified picture

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715612

The therapeutic potential of semi-synthetic artemisinin and synthetic endoperoxide antimalarial agents

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715612

The global distribution of clinical episodes of Plasmodium falciparum malaria

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715612

Reaction of artemisinin with haemoglobin: implications for antimalarial activity

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715612

Identification of an antimalarial synthetic trioxolane drug development candidate

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715612

A medicinal chemistry perspective on artemisinin and related endoperoxides

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715612

Alkylation of human hemoglobin A0 by the antimalarial drug artemisinin.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715612

Artemisinin: mechanisms of action, resistance and toxicity

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715612

Hemoglobin metabolism in the malaria parasite Plasmodium falciparum

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715612

The chemistry, pharmacology, and clinical applications of qinghaosu (artemisinin) and its derivatives

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715612

Artemisinin (qinghaosu): the role of intracellular hemin in its mechanism of antimalarial action

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715612

The effect of ligand size and stereochemistry on the reactivity of the alpha and beta chains within hemoglobin

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715612

Heme activates artemisinin more efficiently than hemin, inorganic iron, or hemoglobin

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715612

Iron-mediated degradation kinetics of substituted dispiro-1,2,4-trioxolane antimalarials.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715612

Re-evaluation of how artemisinins work in light of emerging evidence of in vitro resistance

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715612

Chemical kinetics and aqueous degradation pathways of a new class of synthetic ozonide antimalarials

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715612

Kinetics of iron-mediated artemisinin degradation: effect of solvent composition and iron salt

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715612

Hemichrome formation observed in human haemoglobin A under various buffer conditions.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715612

Alteration of redox stability of hemoglobins A and S by biological buffers

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715612

Iron ligand recognition by monomeric hemoglobins.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715612

Equations for the spectrophotometric analysis of hemoglobin mixtures

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715612

In-vitro interaction of artemisinin with intact human erythrocytes, erythrocyte ghosts, haemoglobin and carbonic anhydrase

18 August 2018

1 reference

12 December 2020

Studies on the reaction of isocyanides with haemproteins

1 reference

12 December 2020

4 Preparation of derivatives of ferrous and ferric hemoglobin

1 reference

12 December 2020

Detection of hemin release during hemoglobin S denaturation

1 reference

12 December 2020

Quaternary Structure Regulates Hemin Dissociation from Human Hemoglobin

1 reference

12 December 2020

A new strategy for structure determination of large proteins in solution without deuteration

1 reference

12 December 2020

Unfolding and release of heme from human hemoglobins A, S and F

1 reference

12 December 2020

Measuring relative rates of hemoglobin oxidation and denaturation

1 reference

12 December 2020

Thermal denaturation procedures for hemoglobin

1 reference

12 December 2020

Alkylation of proteins by artemisinin. Effects of heme, pH, and drug structure

1 reference

12 December 2020

Coupled reactions in hemoglobin. Heme-globin and dimer-dimer association

1 reference

12 December 2020

Drug-protein interactions: two-site binding of heterocyclic ligands to a monomeric hemoglobin

1 reference

12 December 2020

Identifiers

DOI

10.1128/AAC.00363-09

1 reference

14 October 2017

1 reference

14 October 2017

PubMed publication ID

19487440

1 reference