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Crystal structures reveal transient PERK luminal domain tetramerization in endoplasmic reticulum stress signaling.
scientific article published on 28 April 2015
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scholarly article
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stated in
Europe PubMed Central
PMC publication ID
4474532
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25925385%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 March 2020
title
Crystal structures reveal transient PERK luminal domain tetramerization in endoplasmic reticulum stress signaling
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
4474532
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25925385%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 March 2020
main subject
endoplasmic reticulum
0 references
crystal structure
1 reference
based on heuristic
inferred from title
author
Filippo Prischi
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
4474532
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25925385%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 March 2020
Maruf M U Ali
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMC publication ID
4474532
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25925385%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 March 2020
author name string
Marta Carrara
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
4474532
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25925385%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 March 2020
Piotr R Nowak
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
4474532
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25925385%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 March 2020
language of work or name
English
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publication date
28 April 2015
1 reference
stated in
Europe PubMed Central
PMC publication ID
4474532
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25925385%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 March 2020
published in
The EMBO Journal
1 reference
stated in
Europe PubMed Central
PMC publication ID
4474532
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25925385%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 March 2020
volume
34
1 reference
stated in
Europe PubMed Central
PMC publication ID
4474532
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25925385%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 March 2020
issue
11
1 reference
stated in
Europe PubMed Central
PMC publication ID
4474532
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25925385%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 March 2020
page(s)
1589-1600
1 reference
stated in
Europe PubMed Central
PMC publication ID
4474532
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25925385%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 March 2020
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Unfolded proteins are Ire1-activating ligands that directly induce the unfolded protein response
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The crystal structure of human IRE1 luminal domain reveals a conserved dimerization interface required for activation of the unfolded protein response
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Crystal structure of an Hsp90-nucleotide-p23/Sba1 closed chaperone complex
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The protein kinase/endoribonuclease IRE1alpha that signals the unfolded protein response has a luminal N-terminal ligand-independent dimerization domain
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5 June 2018
Oligomerization and phosphorylation of the Ire1p kinase during intracellular signaling from the endoplasmic reticulum to the nucleus
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5 June 2018
The unfolded protein response pathway in Saccharomyces cerevisiae. Oligomerization and trans-phosphorylation of Ire1p (Ern1p) are required for kinase activation
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5 June 2018
Noncanonical binding of BiP ATPase domain to Ire1 and Perk is dissociated by unfolded protein CH1 to initiate ER stress signaling
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Ligand-independent dimerization activates the stress response kinases IRE1 and PERK in the lumen of the endoplasmic reticulum.
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18 August 2018
Identifiers
DOI
10.15252/EMBJ.201489183
1 reference
stated in
Europe PubMed Central
PMC publication ID
4474532
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25925385%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 March 2020
PMC publication ID
4474532
1 reference
stated in
Europe PubMed Central
PMC publication ID
4474532
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25925385%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 March 2020
PubMed publication ID
25925385
1 reference
stated in
Europe PubMed Central
PMC publication ID
4474532
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25925385%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 March 2020
ResearchGate publication ID
275668073
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