(Q24313049)

identical protein binding

GOA release 2020-03-11

1 reference

High-Resolution Structural Characterization of a Helical α/β-Peptide Foldamer Bound to the Anti-Apoptotic Protein Bcl-xL

GOA release 2020-03-11

Shenggen Yao

8

Shenggen

Yao

1 reference

9 December 2023

Erinna F Lee

7

Erinna F

Lee

1 reference

9 December 2023

Ruth M Kluck

12

Ruth M

Kluck

1 reference

9 December 2023

Brian J Smith

10

Brian J

Smith

1 reference

9 December 2023

Colin Hockings

5

Colin

Hockings

1 reference

9 December 2023

6

W Douglas Fairlie

W Douglas

Fairlie

1 reference

9 December 2023

1

Peter E Czabotar

Peter E

Czabotar

1 reference

9 December 2023

13

Jerry M Adams

Jerry M

Adams

1 reference

9 December 2023

11

David C S Huang

David C S

Huang

1 reference

9 December 2023

9

Adeline Y Robin

Adeline Y

Robin

1 reference

9 December 2023

Dana Westphal

2

Dana

Westphal

1 reference

9 December 2023

Grant Dewson

series ordinal

3

author given names

Grant

author last names

Dewson

1 reference

9 December 2023

Stephen Ma

series ordinal

4

author given names

Stephen

author last names

Ma

1 reference

9 December 2023

Peter M Colman

series ordinal

14

author given names

Peter M

author last names

Colman

1 reference

9 December 2023

language of work or name

English

0 references

publication date

31 January 2013

0 references

published in

Cell

0 references

volume

152

0 references

page(s)

519-31

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issue

3

0 references

cites work

1 reference

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7 January 2021

Lessons from the lysozyme of phage T4

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1H, 13C and 15N chemical shift referencing in biomolecular NMR

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7 January 2021

The program XEASY for computer-supported NMR spectral analysis of biological macromolecules

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7 January 2021

Molecular biology of Bax and Bak activation and action

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.12.031

7 January 2021

Mitochondria primed by death signals determine cellular addiction to antiapoptotic BCL-2 family members

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7 January 2021

Apoptosis: embedded in membranes

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7 January 2021

Membrane binding by tBid initiates an ordered series of events culminating in membrane permeabilization by Bax

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7 January 2021

Bcl-x(L) retrotranslocates Bax from the mitochondria into the cytosol

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7 January 2021

BCL-XL dimerization by three-dimensional domain swapping.

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7 January 2021

BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.12.031

7 January 2021

To trigger apoptosis, Bak exposes its BH3 domain and homodimerizes via BH3:groove interactions.

1 reference

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7 January 2021

Baxbeta: a constitutively active human Bax isoform that is under tight regulatory control by the proteasomal degradation mechanism

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7 January 2021

Stepwise activation of BAX and BAK by tBID, BIM, and PUMA initiates mitochondrial apoptosis.

1 reference

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7 January 2021

Bak activation for apoptosis involves oligomerization of dimers via their alpha6 helices

1 reference

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7 January 2021

BH3-triggered structural reorganization drives the activation of proapoptotic BAX.

1 reference

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7 January 2021

A unified model of mammalian BCL-2 protein family interactions at the mitochondria.

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7 January 2021

Pore-forming protein toxins: from structure to function

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7 January 2021

The mechanism of pore formation by bacterial toxins

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7 January 2021

The evolving role of 3D domain swapping in proteins

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7 January 2021

Processing of X-ray diffraction data collected in oscillation mode

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7 January 2021

Heteronuclear multidimensional NMR experiments for the structure determination of proteins in solution employing pulsed field gradients

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7 January 2021

Structure of Bax: coregulation of dimer formation and intracellular localization

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7 January 2021

Bid, Bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane

1 reference

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7 January 2021

The structure of a Bcl-xL/Bim fragment complex: implications for Bim function

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7 January 2021

Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.12.031

7 January 2021

Transbilayer lipid diffusion promoted by Bax: implications for apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.12.031

7 January 2021

Molecular view of the role of fusion peptides in promoting positive membrane curvature.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.12.031

7 January 2021

X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.12.031

7 January 2021

EGL-1 BH3 mutants reveal the importance of protein levels and target affinity for cell-killing potency.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.12.031

7 January 2021

Bax dimerizes via a symmetric BH3:groove interface during apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.12.031

7 January 2021

BAX activation is initiated at a novel interaction site

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7 January 2021

The structure of a cytolytic alpha-helical toxin pore reveals its assembly mechanism

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7 January 2021

Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies

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https://api.crossref.org/works/10.1016%2FJ.CELL.2012.12.031

7 January 2021

BCL-2 family antagonists for cancer therapy

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7 January 2021

The BCL-2 protein family: opposing activities that mediate cell death

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.12.031

7 January 2021

Bax forms multispanning monomers that oligomerize to permeabilize membranes during apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.12.031

7 January 2021

Bak Conformational Changes Induced by Ligand Binding: Insight into BH3 Domain Binding and Bak Homo-Oligomerization

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.12.031

7 January 2021

Structure of transmembrane pore induced by Bax-derived peptide: evidence for lipidic pores.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.12.031

7 January 2021

Apoptosis is triggered when prosurvival Bcl-2 proteins cannot restrain Bax.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.12.031

7 January 2021

Nonconsecutive disulfide bond formation in an essential integral outer membrane protein

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.12.031

7 January 2021

Cytosol-to-membrane redistribution of Bax and Bcl-X(L) during apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.12.031

7 January 2021

Nonionic detergents induce dimerization among members of the Bcl-2 family

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.12.031

7 January 2021

Bax in murine thymus is a soluble monomeric protein that displays differential detergent-induced conformations

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.12.031

7 January 2021

Molecular details of Bax activation, oligomerization, and membrane insertion.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.12.031

7 January 2021

Bax forms an oligomer via separate, yet interdependent, surfaces

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.12.031

7 January 2021

Conformational changes in BAK, a pore-forming proapoptotic Bcl-2 family member, upon membrane insertion and direct evidence for the existence of BH3-BH3 contact interface in BAK homo-oligomers

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.12.031

7 January 2021

Mutation to Bax beyond the BH3 domain disrupts interactions with pro-survival proteins and promotes apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.12.031

7 January 2021

Lipidic pore formation by the concerted action of proapoptotic BAX and tBID.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.12.031

7 January 2021

Movement of Bax from the cytosol to mitochondria during apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.12.031

7 January 2021

Regulated targeting of BAX to mitochondria.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.12.031

7 January 2021

Mitochondrial permeabilization relies on BH3 ligands engaging multiple prosurvival Bcl-2 relatives, not Bak.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.12.031

7 January 2021

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.12.031

1 reference

7 January 2021

The role of BH3-only protein Bim extends beyond inhibiting Bcl-2-like prosurvival proteins

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.12.031

7 January 2021

Transient binding of an activator BH3 domain to the Bak BH3-binding groove initiates Bak oligomerization

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.12.031

7 January 2021

Conformation of the Bax C-terminus regulates subcellular location and cell death

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.12.031

7 January 2021

The expression of a new variant of the pro-apoptotic molecule Bax, Baxpsi, is correlated with an increased survival of glioblastoma multiforme patients

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.12.031

7 January 2021

CASTp: computed atlas of surface topography of proteins with structural and topographical mapping of functionally annotated residues

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.12.031

7 January 2021

A three-helix homo-oligomerization domain containing BH3 and BH1 is responsible for the apoptotic activity of Bax.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.12.031

7 January 2021

Phasercrystallographic software

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.12.031

7 January 2021

Coot: model-building tools for molecular graphics

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.12.031

7 January 2021

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.12.031

1 reference

7 January 2021

PHENIX: a comprehensive Python-based system for macromolecular structure solution

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.12.031

7 January 2021

Crystallization of small proteins assisted by green fluorescent protein

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.12.031

7 January 2021

Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.12.031

7 January 2021

Linking Crystallographic Model and Data Quality

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.12.031

7 January 2021

Structure of Bcl-xL-Bak peptide complex: recognition between regulators of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.12.031

7 January 2021

Mutagenesis of the BH3 domain of BAX identifies residues critical for dimerization and killing

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.12.031

7 January 2021

Bcl-XL inhibits membrane permeabilization by competing with Bax.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.12.031

7 January 2021