(Q41936012)

14 October 2017

MCPH1 patient cells exhibit delayed release from DNA damage-induced G2/M checkpoint arrest (English)

1 reference

14 October 2017

0 references

Ioannis Gavvovidis

1

0 references

Tatsuya Hirano

6

object named as

Tatsuya Hirano

1 reference

14 October 2017

8

Heidemarie Neitzel

1 reference

14 October 2017

7

Detlev Schindler

1 reference

14 October 2017

9

Marc Trimborn

1 reference

Juan Alberto Marchal Ortega

14 October 2017

3

object named as

Juan Alberto Marchal

1 reference

14 October 2017

Charlotte Pöhlmann

2

1 reference

14 October 2017

Markus Stumm

4

1 reference

14 October 2017

Daisuke Yamashita

5

1 reference

14 October 2017

15 December 2010

1 reference

14 October 2017

7

1 reference

based on heuristic

inferred from page(s)

published in

Cell Cycle

1 reference

14 October 2017

9

1 reference

14 October 2017

24

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14 October 2017

4893-4899

1 reference

MCPH1/BRIT1 limits ionizing radiation-induced centrosome amplification.

14 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047812

Establishment of a mouse model with misregulated chromosome condensation due to defective Mcph1 function

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047812

BRIT1/MCPH1 is essential for mitotic and meiotic recombination DNA repair and maintaining genomic stability in mice

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047812

Primary microcephaly: do all roads lead to Rome?

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047812

BRIT1/MCPH1 links chromatin remodelling to DNA damage response.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047812

Human DNA damage response and repair deficiency syndromes: linking genomic instability and cell cycle checkpoint proficiency

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047812

Microcephalin/MCPH1 associates with the Condensin II complex to function in homologous recombination repair.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047812

Differential regulation of centrosome integrity by DNA damage response proteins.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047812

MCPH1 functions in an H2AX-dependent but MDC1-independent pathway in response to DNA damage

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047812

The Drosophila homolog of MCPH1, a human microcephaly gene, is required for genomic stability in the early embryo

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047812

Distinct BRCT domains in Mcph1/Brit1 mediate ionizing radiation-induced focus formation and centrosomal localization.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047812

BRIT1 regulates early DNA damage response, chromosomal integrity, and cancer

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047812

Regulation of mitotic entry by microcephalin and its overlap with ATR signalling

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047812

Misregulated Chromosome Condensation in MCPH1 Primary Microcephaly is Mediated by Condensin II

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047812

BRIT1/MCPH1 is a DNA damage responsive protein that regulates the Brca1-Chk1 pathway, implicating checkpoint dysfunction in microcephaly

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047812

Microcephalin Is a DNA Damage Response Protein Involved in Regulation of CHK1 and BRCA1

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047812

Mutations in microcephalin cause aberrant regulation of chromosome condensation.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047812

Identification of microcephalin, a protein implicated in determining the size of the human brain

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047812

Premature chromosome condensation in humans associated with microcephaly and mental retardation: a novel autosomal recessive condition

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047812

Two molecularly distinct G(2)/M checkpoints are induced by ionizing irradiation

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047812

Involvement of Brca1 in S-phase and G(2)-phase checkpoints after ionizing irradiation

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047812

Entry into mitosis in vertebrate somatic cells is guarded by a chromosome damage checkpoint that reverses the cell cycle when triggered during early but not late prophase

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047812

DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047812

A small step for the cell, a giant leap for mankind: a hypothesis of neocortical expansion during evolution

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047812

5 June 2018

Identifiers

DOI

10.4161/CC.9.24.14157

1 reference

14 October 2017

1 reference

14 October 2017

PubMed publication ID

21150325

1 reference