(Q42027719)

15 October 2017

Integrin signaling in mammary epithelial cells and breast cancer (English)

1 reference

15 October 2017

Arthur W Lambert

1

1 reference

15 October 2017

Sait Ozturk

series ordinal

2

1 reference

15 October 2017

Sam Thiagalingam

series ordinal

3

1 reference

15 October 2017

1 March 2012

1 reference

15 October 2017

1 reference

15 October 2017

2012

1 reference

15 October 2017

493283

1 reference

Creative Commons Attribution 3.0 Unported

15 October 2017

start time

1 March 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

1 reference

April 2022 Public Data File from Crossref

cites work

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A perspective on cancer cell metastasis

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5 June 2018

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Cells of origin in cancer

5 June 2018

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The α₂β₁ integrin is a metastasis suppressor in mouse models and human cancer

5 June 2018

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Integrin signalling adaptors: not only figurants in the cancer story

5 June 2018

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BRCA1 basal-like breast cancers originate from luminal epithelial progenitors and not from basal stem cells

5 June 2018

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Cell-matrix interactions in mammary gland development and breast cancer

5 June 2018

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Targeting breast cancer stem cells

5 June 2018

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Crosstalk between integrin and receptor tyrosine kinase signaling in breast carcinoma progression

5 June 2018

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Matrix metalloproteinase-induced epithelial-mesenchymal transition in breast cancer

5 June 2018

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IAP regulation of metastasis

5 June 2018

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Integrin signaling through FAK in the regulation of mammary stem cells and breast cancer

5 June 2018

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Mutant p53 drives invasion by promoting integrin recycling

5 June 2018

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Integrins in cancer: biological implications and therapeutic opportunities

5 June 2018

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The extracellular matrix: not just pretty fibrils

5 June 2018

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Epithelial-mesenchymal transitions in development and disease

5 June 2018

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Heterogeneity in cancer: cancer stem cells versus clonal evolution

5 June 2018

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An integrin alpha(v)beta(3)-c-Src oncogenic unit promotes anchorage-independence and tumor progression

5 June 2018

1 reference

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Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers

5 June 2018

1 reference

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RCP is a human breast cancer-promoting gene with Ras-activating function

5 June 2018

1 reference

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Mammary epithelial-specific ablation of the focal adhesion kinase suppresses mammary tumorigenesis by affecting mammary cancer stem/progenitor cells

5 June 2018

1 reference

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Integrins in mammary-stem-cell biology and breast-cancer progression--a role in cancer stem cells?

5 June 2018

1 reference

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5 June 2018

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Collagen fibrillogenesis: fibronectin, integrins, and minor collagens as organizers and nucleators

5 June 2018

1 reference

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Integrins in angiogenesis and lymphangiogenesis

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317013

Beta1 integrin deletion from the basal compartment of the mammary epithelium affects stem cells

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317013

5 June 2018

IAPs: what's in a name?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317013

Mammary epithelial-specific disruption of the focal adhesion kinase blocks mammary tumor progression

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317013

Multifaceted roles of integrins in breast cancer metastasis

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317013

Increased invasive potential and up-regulation of MMP-2 in MDA-MB-231 breast cancer cells expressing the beta3 integrin subunit

5 June 2018

1 reference

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Gata-3 is an essential regulator of mammary-gland morphogenesis and luminal-cell differentiation

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317013

Beta3 integrin and Src facilitate transforming growth factor-beta mediated induction of epithelial-mesenchymal transition in mammary epithelial cells

5 June 2018

1 reference

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Of extracellular matrix, scaffolds, and signaling: tissue architecture regulates development, homeostasis, and cancer.

5 June 2018

1 reference

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A novel mechanism for integrin-mediated ras activation in breast carcinoma cells: the alpha6beta4 integrin regulates ErbB2 translation and transactivates epidermal growth factor receptor/ErbB2 signaling

5 June 2018

1 reference

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Generation of a functional mammary gland from a single stem cell

5 June 2018

1 reference

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Purification and unique properties of mammary epithelial stem cells

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317013

Ablation of beta1 integrin in mammary epithelium reveals a key role for integrin in glandular morphogenesis and differentiation.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317013

Beta4 integrin subunit gene expression correlates with tumor size and nuclear grade in early breast cancer

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317013

VEGF-integrin interplay controls tumor growth and vascularization.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317013

Beta1 integrins regulate mammary gland proliferation and maintain the integrity of mammary alveoli

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317013

Integrin signalling during tumour progression

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317013

Integrins in mammary gland development and differentiation of mammary epithelium

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317013

The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317013

Prospective identification of tumorigenic breast cancer cells

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317013

Integrins: bidirectional, allosteric signaling machines

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317013

The alpha(2) integrin subunit-deficient mouse: a multifaceted phenotype including defects of branching morphogenesis and hemostasis

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317013

Adhesion assembly, disassembly and turnover in migrating cells -- over and over and over again

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317013

Sensing the environment: a historical perspective on integrin signal transduction

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317013

Putting tumours in context

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317013

Cell transformation by the middle T-antigen of polyoma virus

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317013

Integrins and cell proliferation: regulation of cyclin-dependent kinases via cytoplasmic signaling pathways

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317013

Integrin activation controls metastasis in human breast cancer

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317013

Molecular portraits of human breast tumours

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317013

FAK integrates growth-factor and integrin signals to promote cell migration

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317013

Integrin function in breast carcinoma progression

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317013

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317013

Integrin-mediated activation of focal adhesion kinase is required for signaling to Jun NH2-terminal kinase and progression through the G1 phase of the cell cycle

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317013

Beta3-integrin-deficient mice are a model for Glanzmann thrombasthenia showing placental defects and reduced survival.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317013

Extensive vasculogenesis, angiogenesis, and organogenesis precede lethality in mice lacking all alpha v integrins

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317013

Integrins induce activation of EGF receptor: role in MAP kinase induction and adhesion-dependent cell survival

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317013

Extracellular matrix signaling: integration of form and function in normal and malignant cells

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317013

Perturbation of beta1-integrin function alters the development of murine mammary gland

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317013

Expression of alphav integrins and vitronectin receptor identity in breast cancer cells

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317013

Cdc42 and Rac1 induce integrin-mediated cell motility and invasiveness through PI(3)K.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317013

5 June 2018

Integrins and anoikis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317013

Integrins can collaborate with growth factors for phosphorylation of receptor tyrosine kinases and MAP kinase activation: roles of integrin aggregation and occupancy of receptors

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317013

Beta4 integrin is required for hemidesmosome formation, cell adhesion and cell survival

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317013

Absence of integrin alpha 6 leads to epidermolysis bullosa and neonatal death in mice.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317013

Localization of matrix metalloproteinase MMP-2 to the surface of invasive cells by interaction with integrin alpha v beta 3.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317013

Deletion of integrin alpha 1 by homologous recombination permits normal murine development but gives rise to a specific deficit in cell adhesion.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317013

Re-expression of the alpha 2 beta 1 integrin abrogates the malignant phenotype of breast carcinoma cells

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317013

Deletion of beta 1 integrins in mice results in inner cell mass failure and peri-implantation lethality

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317013

Decreased expression of integrin adhesive protein receptors in adenocarcinoma of the breast

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317013

Integrins and their accessory adhesion molecules in mammary carcinomas: loss of polarization in poorly differentiated tumors

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317013

Beta 4 integrin amplifies ErbB2 signaling to promote mammary tumorigenesis.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317013

Targeted disruption of beta1-integrin in a transgenic mouse model of human breast cancer reveals an essential role in mammary tumor induction.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317013

Epithelial development and differentiation in the mammary gland is not dependent on alpha 3 or alpha 6 integrin subunits.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317013

Alpha 6 beta 4 and alpha 6 beta 1 integrins associate with ErbB-2 in human carcinoma cell lines.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317013

Changes in integrin receptors on oncogenically transformed cells.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317013

Integrin β4 signaling promotes tumor angiogenesis

17 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.5402%2F2012%2F493283

Embryonic mesodermal defects in alpha 5 integrin-deficient mice

21 January 2018

1 reference

12 December 2020

High expression level of alpha 6 integrin in human breast carcinoma is correlated with reduced survival

1 reference

12 December 2020

Alpha 3 beta 1 integrin has a crucial role in kidney and lung organogenesis

1 reference

12 December 2020

Integrin alpha V beta 3 expression by bone-residing breast cancer metastases

1 reference

12 December 2020

An entire functional mammary gland may comprise the progeny from a single cell

1 reference

12 December 2020

The mammary progenitor marker CD61/beta3 integrin identifies cancer stem cells in mouse models of mammary tumorigenesis

1 reference

12 December 2020

Laminin and beta1 integrins are crucial for normal mammary gland development in the mouse

1 reference

12 December 2020

Identifiers

DOI

10.5402/2012/493283

1 reference

15 October 2017

1 reference

15 October 2017

PubMed publication ID

22523705

1 reference