(Q42050305)

4 July 2018

title

Binding of the cytoplasmic domain of CD28 to the plasma membrane inhibits Lck recruitment and signaling (English)

1 reference

4 July 2018

7

Kai W Wucherpfennig

1 reference

4 July 2018

author name string

Jessica Dobbins

1

1 reference

4 July 2018

Etienne Gagnon

2

1 reference

4 July 2018

Jernej Godec

3

1 reference

4 July 2018

Jason Pyrdol

4

1 reference

4 July 2018

Dario A A Vignali

5

1 reference

4 July 2018

Arlene H Sharpe

6

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4 July 2018

publication date

26 July 2016

1 reference

4 July 2018

published in

Science Signaling

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4 July 2018

volume

9

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4 July 2018

issue

438

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4 July 2018

page(s)

ra75

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4 July 2018

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5929992/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

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CD28 promotes CD4+ T cell clonal expansion during infection independently of its YMNM and PYAP motifs.

10 July 2018

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A motif in the V3 domain of the kinase PKC-θ determines its localization in the immunological synapse and functions in T cells via association with CD28

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Induction of autoimmune disease in CTLA-4-/- mice depends on a specific CD28 motif that is required for in vivo costimulation

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CD28 costimulation of developing thymocytes induces Foxp3 expression and regulatory T cell differentiation independently of interleukin 2.

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CD28-mediated co-stimulation: a quantitative support for TCR signalling

10 July 2018

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A Zinc Clasp Structure Tethers Lck to T Cell Coreceptors CD4 and CD8

10 July 2018

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CD45 ectodomain controls interaction with GEMs and Lck activity for optimal TCR signaling

10 July 2018

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10 July 2018

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B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes

10 July 2018

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Regulation of protein kinase Ctheta function during T cell activation by Lck-mediated tyrosine phosphorylation

10 July 2018

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Studies in B7-deficient mice reveal a critical role for B7 costimulation in both induction and effector phases of experimental autoimmune encephalomyelitis

10 July 2018

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Proline residues in CD28 and the Src homology (SH)3 domain of Lck are required for T cell costimulation

10 July 2018

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Expression of the p56(Lck) Y505F mutation in CD45-deficient mice rescues thymocyte development

10 July 2018

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Identification of tyrosine phosphorylation sites in the CD28 cytoplasmic domain and their role in the costimulation of Jurkat T cells

10 July 2018

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Cloned dendritic cells can present exogenous antigens on both MHC class I and class II molecules

10 July 2018

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Analysis of CD28 cytoplasmic tail tyrosine residues as regulators and substrates for the protein tyrosine kinases, EMT and LCK.

10 July 2018

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Selective modulation of protein kinase C-theta during T-cell activation

10 July 2018

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Structural basis for activation of human lymphocyte kinase Lck upon tyrosine phosphorylation

10 July 2018

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Mass Spectrometric Sequencing of Proteins from Silver-Stained Polyacrylamide Gels

10 July 2018

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CD45 specifically modulates binding of Lck to a phosphopeptide encompassing the negative regulatory tyrosine of Lck.

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5929992

Binding of phosphatidylinositol-3-OH kinase to CD28 is required for T-cell signalling

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5929992

The CD45 tyrosine phosphatase regulates specific pools of antigen receptor-associated p59fyn and CD4-associated p56lck tyrosine in human T-cells.

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5929992

T-cell antigen CD28 interacts with the lipid kinase phosphatidylinositol 3-kinase by a cytoplasmic Tyr(P)-Met-Xaa-Met motif

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5929992

T cell antigen CD28 binds to the GRB-2/SOS complex, regulators of p21ras

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5929992

Cloning of B7-2: a CTLA-4 counter-receptor that costimulates human T cell proliferation

10 July 2018

1 reference

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Differential T cell costimulatory requirements in CD28-deficient mice

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5929992

Selective CD28pYMNM mutations implicate phosphatidylinositol 3-kinase in CD86-CD28-mediated costimulation

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5929992

p56Lck and p59Fyn regulate CD28 binding to phosphatidylinositol 3-kinase, growth factor receptor-bound protein GRB-2, and T cell-specific protein-tyrosine kinase ITK: implications for T-cell costimulation

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5929992

CD28 is associated with and induces the immediate tyrosine phosphorylation and activation of the Tec family kinase ITK/EMT in the human Jurkat leukemic T-cell line

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5929992

Structure of the regulatory domains of the Src-family tyrosine kinase Lck

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5929992

Activation of calcium and phospholipid-dependent protein kinase by diacylglycerol, its possible relation to phosphatidylinositol turnover.

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5929992

Molecular cloning of a CD28 cDNA by a high-efficiency COS cell expression system

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5929992

B-cell surface antigen B7 provides a costimulatory signal that induces T cells to proliferate and secrete interleukin 2.

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5929992

CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5929992

Structure Induction of the T-Cell Receptor ζ-Chain upon Lipid Binding Investigated by NMR Spectroscopy

10 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAF0626

Translational activation of the lck proto-oncogene

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAF0626

Phosphorylation of T cell receptor zeta is regulated by a lipid dependent folding transition

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27460989

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Inhibition of antigen-specific proliferation of type 1 murine T cell clones after stimulation with immobilized anti-CD3 monoclonal antibody

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27460989

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1126/SCISIGNAL.AAF0626

1 reference

4 July 2018

PMCID

5929992

1 reference

4 July 2018

PubMed ID

27460989

1 reference

4 July 2018