(Q42086120)

English

A hypoxia-induced positive feedback loop promotes hypoxia-inducible factor 1alpha stability through miR-210 suppression of glycerol-3-phosphate dehydrogenase 1-like

scientific article published on 9 May 2011

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

A hypoxia-induced positive feedback loop promotes hypoxia-inducible factor 1alpha stability through miR-210 suppression of glycerol-3-phosphate dehydrogenase 1-like (English)

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

0 references

author name string

Timothy J Kelly

1

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

Amanda L Souza

2

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

Clary B Clish

3

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

Pere Puigserver

4

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

language of work or name

0 references

publication date

9 May 2011

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

Molecular and Cellular Biology

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

31

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

13

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

2696-2706

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

miR-210 is overexpressed in late stages of lung cancer and mediates mitochondrial alterations associated with modulation of HIF-1 activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133367

30 May 2018

Hypoxia-regulated microRNA-210 modulates mitochondrial function and decreases ISCU and COX10 expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133367

30 May 2018

MicroRNA-210 regulates mitochondrial free radical response to hypoxia and krebs cycle in cancer cells by targeting iron sulfur cluster protein ISCU

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133367

30 May 2018

Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133367

30 May 2018

An integrated approach for experimental target identification of hypoxia-induced miR-210

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133367

30 May 2018

MicroRNA-210 controls mitochondrial metabolism during hypoxia by repressing the iron-sulfur cluster assembly proteins ISCU1/2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133367

30 May 2018

GPD1L links redox state to cardiac excitability by PKC-dependent phosphorylation of the sodium channel SCN5A

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133367

30 May 2018

MicroRNA miR-210 modulates cellular response to hypoxia through the MYC antagonist MNT.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133367

30 May 2018

Elevated expression of microRNAs 155, 203, 210 and 222 in pancreatic tumors is associated with poorer survival

1 reference

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30 May 2018

miR-210 promotes osteoblastic differentiation through inhibition of AcvR1b

1 reference

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30 May 2018

Regulation of cancer cell metabolism by hypoxia-inducible factor 1.

1 reference

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30 May 2018

Roles of p53, MYC and HIF-1 in regulating glycolysis - the seventh hallmark of cancer

1 reference

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30 May 2018

Four miRNAs associated with aggressiveness of lymph node-negative, estrogen receptor-positive human breast cancer

1 reference

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30 May 2018

Identification of an alternative mechanism of degradation of the hypoxia-inducible factor-1alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133367

30 May 2018

Oxygen sensing by metazoans: the central role of the HIF hydroxylase pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133367

30 May 2018

MicroRNA-210 modulates endothelial cell response to hypoxia and inhibits the receptor tyrosine kinase ligand Ephrin-A3

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133367

30 May 2018

hsa-miR-210 Is induced by hypoxia and is an independent prognostic factor in breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133367

30 May 2018

Role and regulation of prolyl hydroxylase domain proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133367

30 May 2018

Mutation in glycerol-3-phosphate dehydrogenase 1 like gene (GPD1-L) decreases cardiac Na+ current and causes inherited arrhythmias

1 reference

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30 May 2018

Molecular and functional characterization of novel glycerol-3-phosphate dehydrogenase 1 like gene (GPD1-L) mutations in sudden infant death syndrome

1 reference

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30 May 2018

Hypoxia-inducible factor 1 (HIF-1) pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133367

30 May 2018

MicroRNA sponges: competitive inhibitors of small RNAs in mammalian cells

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30 May 2018

An mRNA m7G cap binding-like motif within human Ago2 represses translation

1 reference

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30 May 2018

MicroRNA silencing through RISC recruitment of eIF6

1 reference

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30 May 2018

Carbodiimide-mediated cross-linking of RNA to nylon membranes improves the detection of siRNA, miRNA and piRNA by northern blot

1 reference

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30 May 2018

A microRNA signature of hypoxia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133367

30 May 2018

mRNA degradation by miRNAs and GW182 requires both CCR4:NOT deadenylase and DCP1:DCP2 decapping complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133367

30 May 2018

Crystal structures of human glycerol 3-phosphate dehydrogenase 1 (GPD1)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133367

30 May 2018

OS-9 interacts with hypoxia-inducible factor 1alpha and prolyl hydroxylases to promote oxygen-dependent degradation of HIF-1alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133367

30 May 2018

Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase

1 reference

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30 May 2018

Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets

1 reference

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Cancer genes and the pathways they control

1 reference

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30 May 2018

Differential function of the prolyl hydroxylases PHD1, PHD2, and PHD3 in the regulation of hypoxia-inducible factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133367

30 May 2018

Prediction of mammalian microRNA targets

1 reference

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30 May 2018

Targeting HIF-1 for cancer therapy

1 reference

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30 May 2018

HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1alpha in normoxia

1 reference

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Lentivirus-delivered stable gene silencing by RNAi in primary cells

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30 May 2018

Hypoxia-inducible factor-1-dependent regulation of the multidrug resistance (MDR1) gene.

1 reference

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30 May 2018

Structure of an HIF-1alpha -pVHL complex: hydroxyproline recognition in signaling

1 reference

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30 May 2018

C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

1 reference

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30 May 2018

Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation

1 reference

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30 May 2018

Induction of HIF-1alpha in response to hypoxia is instantaneous

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133367

30 May 2018

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

1 reference

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30 May 2018

The Expression and Distribution of the Hypoxia-Inducible Factors HIF-1α and HIF-2α in Normal Human Tissues, Cancers, and Tumor-Associated Macrophages

1 reference

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Redox-regulated recruitment of the transcriptional coactivators CREB-binding protein and SRC-1 to hypoxia-inducible factor 1alpha

1 reference

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Overexpression of hypoxia-inducible factor 1alpha in common human cancers and their metastases

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Signal transduction in hypoxic cells: inducible nuclear translocation and recruitment of the CBP/p300 coactivator by the hypoxia-inducible factor-1alpha

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30 May 2018

Hypoxia-inducible factor 1alpha (HIF-1alpha) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes

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30 May 2018

Activation of hypoxia-inducible transcription factor depends primarily upon redox-sensitive stabilization of its alpha subunit

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Functional interference between hypoxia and dioxin signal transduction pathways: competition for recruitment of the Arnt transcription factor

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Hsp90 regulates a von Hippel Lindau-independent hypoxia-inducible factor-1 alpha-degradative pathway

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Structural consequences of sequence patterns in the fingerprint region of the nucleotide binding fold. Implications for nucleotide specificity

1 reference

https://pubmed.ncbi.nlm.nih.gov/21555452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Low levels of soluble DPN-linked alpha-glycerophosphate dehydrogenase in tumors

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/MCB.01242-10

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 October 2017

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