(Q42132462)

English

An Analysis of All the Relevant Facts and Arguments Indicates that Enzyme Catalysis Does Not Involve Large Contributions from Nuclear Tunneling

scientific article published on July 2010

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

An Analysis of All the Relevant Facts and Arguments Indicates that Enzyme Catalysis Does Not Involve Large Contributions from Nuclear Tunneling (English)

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

Shina Caroline Lynn Kamerlin

1

object named as

Shina C L Kamerlin

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

2

object named as

Arieh Warshel

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

publication date

1 July 2010

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

Journal of Physical Organic Chemistry

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

23

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

7

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

677-684

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

Enzymology takes a quantum leap forward

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3074379

29 May 2018

On the relationship between folding and chemical landscapes in enzyme catalysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3074379

29 May 2018

Enzyme structure and dynamics affect hydrogen tunneling: The impact of a remote side chain (I553) in soybean lipoxygenase-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3074379

29 May 2018

Coupling of hydrogenic tunneling to active-site motion in the hydrogen radical transfer catalyzed by a coenzyme B12-dependent mutase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3074379

29 May 2018

A new paradigm for electrostatic catalysis of radical reactions in vitamin B12 enzymes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3074379

29 May 2018

A combined quantum mechanical and molecular mechanical study of the reaction mechanism and alpha-amino acidity in alanine racemase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3074379

29 May 2018

Modeling electrostatic effects in proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3074379

29 May 2018

Extended spin-boson model for nonadiabatic hydrogen tunneling in the condensed phase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3074379

29 May 2018

Coordinated effects of distal mutations on environmentally coupled tunneling in dihydrofolate reductase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3074379

29 May 2018

Electrostatic basis for enzyme catalysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3074379

29 May 2018

Transition state theory can be used in studies of enzyme catalysis: lessons from simulations of tunnelling and dynamical effects in lipoxygenase and other systems

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3074379

29 May 2018

Small temperature dependence of the kinetic isotope effect for the hydride transfer reaction catalyzed by Escherichia coli dihydrofolate reductase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3074379

29 May 2018

Relating protein motion to catalysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3074379

29 May 2018

Dynamical contributions to enzyme catalysis: critical tests of a popular hypothesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3074379

29 May 2018

Atomic description of an enzyme reaction dominated by proton tunneling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3074379

29 May 2018

Structural bases of hydrogen tunneling in enzymes: progress and puzzles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3074379

29 May 2018

Enzymes: By chance, or by design?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3074379

29 May 2018

Simulations of the large kinetic isotope effect and the temperature dependence of the hydrogen atom transfer in lipoxygenase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3074379

29 May 2018

Apparent NAC effect in chorismate mutase reflects electrostatic transition state stabilization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3074379

29 May 2018

A compelling experimental test of the hypothesis that enzymes have evolved to enhance quantum mechanical tunneling in hydrogen transfer reactions: the beta-neopentylcobalamin system combined with prior adocobalamin data

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3074379

29 May 2018

Environmentally coupled hydrogen tunneling. Linking catalysis to dynamics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3074379

29 May 2018

Molecular dynamics simulations of biological reactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3074379

29 May 2018

Quantum mechanical methods for enzyme kinetics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3074379

29 May 2018

Temperature-dependent isotope effects in soybean lipoxygenase-1: correlating hydrogen tunneling with protein dynamics.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3074379

29 May 2018

Dynamics of biochemical and biophysical reactions: insight from computer simulations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3074379

29 May 2018

The depth of chemical time and the power of enzymes as catalysts.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3074379

29 May 2018

Hydride transfer in liver alcohol dehydrogenase: quantum dynamics, kinetic isotope effects, and role of enzyme motion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3074379

29 May 2018

A link between protein structure and enzyme catalyzed hydrogen tunneling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3074379

29 May 2018

A proficient enzyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3074379

29 May 2018

Quantum mechanical effects in enzyme-catalysed hydrogen transfer reactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3074379

29 May 2018

Vibrationally enhanced tunneling as a mechanism for enzymatic hydrogen transfer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3074379

29 May 2018

Charge stabilization mechanism in the visual and purple membrane pigments

1 reference

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29 May 2018

On the interpretation of the observed linear free energy relationship in phosphate hydrolysis: a thorough computational study of phosphate diester hydrolysis in solution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3074379

17 August 2018

Origin of the temperature dependence of isotope effects in enzymatic reactions: the case of dihydrofolate reductase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3074379

17 August 2018

The catalytic effect of dihydrofolate reductase and its mutants is determined by reorganization energies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3074379

17 August 2018

Electrostatic contributions to binding of transition state analogues can be very different from the corresponding contributions to catalysis: phenolates binding to the oxyanion hole of ketosteroid isomerase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3074379

17 August 2018

On the mechanism of hydrolysis of phosphate monoesters dianions in solutions and proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3074379

17 August 2018

Hybrid quantum/classical path integral approach for simulation of hydrogen transfer reactions in enzymes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3074379

17 August 2018

Hydride transfer reaction catalyzed by hyperthermophilic dihydrofolate reductase is dominated by quantum mechanical tunneling and is promoted by both inter- and intramonomeric correlated motions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3074379

17 August 2018

Coupling of protein motions and hydrogen transfer during catalysis by Escherichia coli dihydrofolate reductase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3074379

17 August 2018

How the Co-C bond is cleaved in coenzyme B12 enzymes: a theoretical study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3074379

17 August 2018

Promoting vibrations in human purine nucleoside phosphorylase. A molecular dynamics and hybrid quantum mechanical/molecular mechanical study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3074379

17 August 2018

Proton-coupled electron transfer in soybean lipoxygenase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3074379

17 August 2018

The first experimental test of the hypothesis that enzymes have evolved to enhance hydrogen tunneling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3074379

17 August 2018

Electrostatic origin of the catalytic power of enzymes and the role of preorganized active sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3074379

17 August 2018

A crosslinked cofactor in lysyl oxidase: redox function for amino acid side chains.

1 reference

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17 August 2018

Density-functional investigation on the mechanism of H-atom abstraction by lipoxygenase

1 reference

https://pubmed.ncbi.nlm.nih.gov/21494414

12 December 2020

based on heuristic

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Enzyme dynamics and tunneling enhanced by compression in the hydrogen abstraction catalyzed by soybean lipoxygenase-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/21494414

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nuclear quantum effects on an enzyme-catalyzed reaction with reaction path potential: proton transfer in triosephosphate isomerase

1 reference

https://pubmed.ncbi.nlm.nih.gov/21494414

12 December 2020

based on heuristic

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Computer simulation of primary kinetic isotope effects in the proposed rate-limiting step of the glyoxalase I catalyzed reaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/21494414

12 December 2020

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Multidimensional tunneling, recrossing, and the transmission coefficient for enzymatic reactions

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/POC.1620

How enzymes work: analysis by modern rate theory and computer simulations

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/POC.1620

Solvent polarization and kinetic isotope effects in nitroethane deprotonation and implications to the nitroalkane oxidase reaction.

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11 October 2022

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DNA polymerase beta catalysis: are different mechanisms possible?

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/POC.1620

Quantum dynamics of hydride transfer catalyzed by bimetallic electrophilic catalysis: synchronous motion of Mg(2+) and H(-) in xylose isomerase

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/POC.1620

Quantum Dynamics of Hydride Transfer in Enzyme Catalysis

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/POC.1620

Simulation of enzyme reactions using valence bond force fields and other hybrid quantum/classical approaches

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/POC.1620

Mechanism for electron transfer within and between proteins

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11 October 2022

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Identifiers

10.1002/POC.1620

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

ResearchGate publication ID

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