(Q42155363)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23814078%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

title

Cell cycle-dependent subcellular translocation of the human DNA licensing inhibitor geminin (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23814078%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23814078%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Hideo Nishitani

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23814078%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

7

Zoi Lygerou

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23814078%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

author name string

Maria Dimaki

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23814078%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Georgia Xouri

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23814078%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Ioanna-Eleni Symeonidou

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23814078%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Chaido Sirinian

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23814078%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

language of work or name

English

0 references

publication date

29 June 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23814078%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

4 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23814078%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

volume

288

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23814078%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

issue

33

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23814078%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

page(s)

23953-23963

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23814078%20AND%20SRC:MED&resulttype=core&format=json

Control over DNA replication in time and space

4 March 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3745341

Idas, a novel phylogenetically conserved geminin-related protein, binds to geminin and is required for cell cycle progression

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3745341

Quaternary structure of the human Cdt1-Geminin complex regulates DNA replication licensing

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3745341

Selective killing of cancer cells by suppression of geminin activity

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3745341

Regulation of geminin functions by cell cycle-dependent nuclear-cytoplasmic shuttling

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3745341

Cdt1 associates dynamically with chromatin throughout G1 and recruits Geminin onto chromatin

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3745341

Geminin cleavage during apoptosis by caspase-3 alters its binding ability to the SWI/SNF subunit Brahma

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3745341

A Cdt1-geminin complex licenses chromatin for DNA replication and prevents rereplication during S phase in Xenopus

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3745341

Geminin is essential to prevent endoreduplication and to form pluripotent cells during mammalian development

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3745341

Gene Expression Profiling of Primary Cutaneous Melanoma and Clinical Outcome

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3745341

CDKs promote DNA replication origin licensing in human cells by protecting Cdc6 from APC/C-dependent proteolysis

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3745341

Geminin regulates neuronal differentiation by antagonizing Brg1 activity

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3745341

Repression of DNA replication licensing in quiescence is independent of geminin and may define the cell cycle state of progenitor cells

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3745341

Geminin-Cdt1 balance is critical for genetic stability

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3745341

Regulation of early events in chromosome replication

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3745341

Geminin has dimerization, Cdt1-binding, and destruction domains that are required for biological activity

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3745341

Cdt1 and geminin are down-regulated upon cell cycle exit and are over-expressed in cancer-derived cell lines

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3745341

Rereplication by depletion of geminin is seen regardless of p53 status and activates a G2/M checkpoint

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3745341

Human geminin promotes pre-RC formation and DNA replication by stabilizing CDT1 in mitosis

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3745341

Loss of Geminin induces rereplication in the presence of functional p53

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3745341

Negative regulation of geminin by CDK-dependent ubiquitination controls replication licensing.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3745341

Non-proteolytic inactivation of geminin requires CDK-dependent ubiquitination.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3745341

Cell type-specific responses of human cells to inhibition of replication licensing

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3745341

Geminin becomes activated as an inhibitor of Cdt1/RLF-B following nuclear import.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3745341

Control of DNA replication and chromosome ploidy by geminin and cyclin A

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3745341

The human licensing factor for DNA replication Cdt1 accumulates in G1 and is destabilized after initiation of S-phase

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3745341

Repression of origin assembly in metaphase depends on inhibition of RLF-B/Cdt1 by geminin

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3745341

Inhibition of eukaryotic DNA replication by geminin binding to Cdt1

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3745341

The Cdt1 protein is required to license DNA for replication in fission yeast

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3745341

Cell cycle-regulated expression of mammalian CDC6 is dependent on E2F.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3745341

Geminin, an inhibitor of DNA replication, is degraded during mitosis

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3745341

Cdc6 is regulated by E2F and is essential for DNA replication in mammalian cells

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3745341

Expression of the HsOrc1 gene, a human ORC1 homolog, is regulated by cell proliferation via the E2F transcription factor

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3745341

Cyclin from sea urchins to HeLas: making the human cell cycle

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3745341

Reduced Geminin levels promote cellular senescence

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3745341

Subcellular translocation signals regulate Geminin activity during embryonic development.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3745341

Intrinsic nuclear import activity of geminin is essential to prevent re-initiation of DNA replication in Xenopus eggs.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3745341

Regulation of Geminin and Cdt1 expression by E2F transcription factors

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3745341

Protein kinase CK2 phosphorylates the cell cycle regulatory protein Geminin.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3745341

CUL-4 ubiquitin ligase maintains genome stability by restraining DNA-replication licensing

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3745341

Recombinant Cdt1 induces rereplication of G2 nuclei in Xenopus egg extracts

17 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23814078

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Stepwise Regulated Chromatin Assembly of MCM2–7 Proteins

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23814078

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M113.453092

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23814078%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23814078%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

1 reference