(Q42169313)

English

Hypersensitivity of nonhomologous DNA end-joining mutants to VP-16 and ICRF-193: implications for the repair of topoisomerase II-mediated DNA damage

scientific article published on 3 July 2003

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

17 October 2017

Hypersensitivity of nonhomologous DNA end-joining mutants to VP-16 and ICRF-193: implications for the repair of topoisomerase II-mediated DNA damage (English)

1 reference

Europe PubMed Central

PubMed publication ID

17 October 2017

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1 reference

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author name string

Noritaka Adachi

1

1 reference

Europe PubMed Central

PubMed publication ID

17 October 2017

Hiromi Suzuki

2

1 reference

Europe PubMed Central

PubMed publication ID

17 October 2017

Susumu Iiizumi

3

1 reference

Europe PubMed Central

PubMed publication ID

17 October 2017

Hideki Koyama

4

1 reference

Europe PubMed Central

PubMed publication ID

17 October 2017

language of work or name

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publication date

3 July 2003

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Europe PubMed Central

PubMed publication ID

17 October 2017

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

17 October 2017

278

1 reference

Europe PubMed Central

PubMed publication ID

17 October 2017

38

1 reference

Europe PubMed Central

PubMed publication ID

17 October 2017

35897-35902

1 reference

Europe PubMed Central

PubMed publication ID

17 October 2017

Double strand break repair

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306500200

21 January 2018

Molecular mechanisms of DNA double strand break repair

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306500200

21 January 2018

Homology-directed repair is a major double-strand break repair pathway in mammalian cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306500200

21 January 2018

The biochemistry and biological significance of nonhomologous DNA end joining: an essential repair process in multicellular eukaryotes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306500200

21 January 2018

Catalysis of ATP-dependent homologous DNA pairing and strand exchange by yeast RAD51 protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306500200

21 January 2018

Human Rad51 protein promotes ATP-dependent homologous pairing and strand transfer reactions in vitro

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306500200

21 January 2018

Activities of human recombination protein Rad51.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306500200

21 January 2018

Homologous DNA pairing by human recombination factors Rad51 and Rad54

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306500200

21 January 2018

Targeted inactivation of mouse RAD52 reduces homologous recombination but not resistance to ionizing radiation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306500200

21 January 2018

Homologous recombination, but not DNA repair, is reduced in vertebrate cells deficient in RAD52.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306500200

21 January 2018

Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D)J recombination

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306500200

21 January 2018

DNA ligase IV and XRCC4 form a stable mixed tetramer that functions synergistically with other repair factors in a cell-free end-joining system

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306500200

21 January 2018

DNA ligase IV is essential for V(D)J recombination and DNA double-strand break repair in human precursor lymphocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306500200

21 January 2018

DNA ligase IV-deficient cells are more resistant to ionizing radiation in the absence of Ku70: Implications for DNA double-strand break repair

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306500200

21 January 2018

Homologous recombination and non-homologous end-joining pathways of DNA double-strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306500200

21 January 2018

Late embryonic lethality and impaired V(D)J recombination in mice lacking DNA ligase IV

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306500200

21 January 2018

Identification of a defect in DNA ligase IV in a radiosensitive leukaemia patient

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306500200

21 January 2018

Identification of a mutated DNA ligase IV gene in the X-ray-hypersensitive mutant SX10 of mouse FM3A cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306500200

21 January 2018

Ku70-deficient embryonic stem cells have increased ionizing radiosensitivity, defective DNA end-binding activity, and inability to support V(D)J recombination

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306500200

21 January 2018

Genetic analysis of the DNA-dependent protein kinase reveals an inhibitory role of Ku in late S-G2 phase DNA double-strand break repair

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306500200

21 January 2018

Increased ratio of targeted to random integration after transfection of chicken B cell lines.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306500200

21 January 2018

DNA topoisomerases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306500200

21 January 2018

Enforced cytokinesis without complete nuclear division in embryonic cells depleting the activity of DNA topoisomerase IIalpha

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306500200

21 January 2018

DNA topoisomerase IIbeta and neural development

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306500200

21 January 2018

Cell-cycle regulation of the DNA topoisomerase IIalpha promoter is mediated by proximal CCAAT boxes: possible involvement of acetylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306500200

21 January 2018

DNA topoisomerase poisons as antitumor drugs

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306500200

21 January 2018

Antitopoisomerase drug action and resistance

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306500200

21 January 2018

Antitumor bisdioxopiperazines inhibit yeast DNA topoisomerase II by trapping the enzyme in the form of a closed protein clamp

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306500200

21 January 2018

Characterization of a Chinese hamster ovary cell line with acquired resistance to the bisdioxopiperazine dexrazoxane (ICRF-187) catalytic inhibitor of topoisomerase II.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306500200

21 January 2018

Differential expression of topoisomerase I and RAD52 protein in yeast reveals new facets of the mechanism of action of bisdioxopiperazine compounds

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306500200

21 January 2018

Decreased topoisomerase IIalpha expression confers increased resistance to ICRF-193 as well as VP-16 in mouse embryonic stem cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306500200

21 January 2018

Etoposide-induced cell cycle delay and arrest-dependent modulation of DNA topoisomerase II in small-cell lung cancer cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306500200

21 January 2018

26 S proteasome-mediated degradation of topoisomerase II cleavable complexes.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306500200

21 January 2018

Endonuclease cleavage of blocked replication forks: An indirect pathway of DNA damage from antitumor drug–topoisomerase complexes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306500200

21 January 2018

DNA topoisomerase-targeting antitumor drugs can be studied in yeast

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306500200

21 January 2018

Differential etoposide sensitivity of cells deficient in the Ku and DNA-PKcs components of the DNA-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306500200

21 January 2018

The topoisomerase IIbeta circular clamp arrests transcription and signals a 26S proteasome pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306500200

21 January 2018

Hypersensitivity of Ku-deficient cells toward the DNA topoisomerase II inhibitor ICRF-193 suggests a novel role for Ku antigen during the G2 and M phases of the cell cycle

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306500200

21 January 2018

Vertebrate cells lacking FEN-1 endonuclease are viable but hypersensitive to methylating agents and H2O2.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306500200

21 January 2018

DNA double-strand breaks associated with replication forks are predominantly repaired by homologous recombination involving an exchange mechanism in mammalian cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306500200

21 January 2018

Different roles for nonhomologous end joining and homologous recombination following replication arrest in mammalian cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306500200

21 January 2018

Topoisomerase II poisoning by ICRF-193.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306500200

21 January 2018

DNA topoisomerase II inhibitors enhance random integration of transfected vectors into human chromosomes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306500200

21 January 2018

Apurinic sites are position-specific topoisomerase II poisons.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306500200

21 January 2018

DNA abasic lesions in a different light: solution structure of an endogenous topoisomerase II poison.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306500200

21 January 2018

Base excision repair intermediates as topoisomerase II poisons

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306500200

21 January 2018

Acidic pH induces topoisomerase II-mediated DNA damage.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306500200

21 January 2018

Identifiers

10.1074/JBC.M306500200

1 reference

Europe PubMed Central

PubMed publication ID

17 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

17 October 2017

ResearchGate publication ID

0 references

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