(Q42231090)

English

Determining P-glycoprotein-drug interactions: evaluation of reconstituted P-glycoprotein in a liposomal system and LLC-MDR1 polarized cell monolayers

scientific article published on 26 February 2012

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

Determining P-glycoprotein-drug interactions: evaluation of reconstituted P-glycoprotein in a liposomal system and LLC-MDR1 polarized cell monolayers (English)

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

Frances J. Sharom

2

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

author name string

Donald L Melchior

1

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

Raymond Evers

3

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

George E Wright

4

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

Joseph W K Chu

5

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

Stephen E Wright

6

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

Xiaoyan Chu

7

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

Jocelyn Yabut

8

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

publication date

26 February 2012

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

Journal of Pharmacological and Toxicological Methods

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

65

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

2

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

64-74

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

Molecular dissection of dual pseudosymmetric solute translocation pathways in human P-glycoprotein.

1 reference

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26 October 2017

Membrane transporters in drug development

1 reference

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26 October 2017

ABC efflux pump-based resistance to chemotherapy drugs.

1 reference

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26 October 2017

Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322284

26 October 2017

Synthesis and biological evaluation of a small molecule library of 3rd generation multidrug resistance modulators

1 reference

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26 October 2017

ABC multidrug transporters: structure, function and role in chemoresistance.

1 reference

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26 October 2017

Kinetic identification of membrane transporters that assist P-glycoprotein-mediated transport of digoxin and loperamide through a confluent monolayer of MDCKII-hMDR1 cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322284

26 October 2017

In vitro P-glycoprotein assays to predict the in vivo interactions of P-glycoprotein with drugs in the central nervous system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322284

26 October 2017

P-glycoprotein (ABCB1) interacts directly with lipid-based anti-cancer drugs and platelet-activating factors

1 reference

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26 October 2017

Development and characterization of LLC-PK1 cells containing Sprague-Dawley rat Abcb1a (Mdr1a): comparison of rat P-glycoprotein transport to human and mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322284

26 October 2017

In vitro p-glycoprotein inhibition assays for assessment of clinical drug interaction potential of new drug candidates: a recommendation for probe substrates.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322284

26 October 2017

The translocation mechanism of P-glycoprotein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322284

26 October 2017

Evaluation of inhibitory potencies for compounds inhibiting P-glycoprotein but without maximum effects: f2 values

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322284

26 October 2017

Interaction of LDS-751 and rhodamine 123 with P-glycoprotein: evidence for simultaneous binding of both drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322284

26 October 2017

Multidrug resistance proteins: role of P-glycoprotein, MRP1, MRP2, and BCRP (ABCG2) in tissue defense

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322284

26 October 2017

Rational use of in vitro P-glycoprotein assays in drug discovery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322284

26 October 2017

Intrinsic fluorescence of the P-glycoprotein multidrug transporter: sensitivity of tryptophan residues to binding of drugs and nucleotides.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322284

26 October 2017

Pharmacological insights from P-glycoprotein knockout mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322284

26 October 2017

Positively cooperative sites for drug transport by P-glycoprotein with distinct drug specificities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322284

26 October 2017

The P-glycoprotein efflux pump: how does it transport drugs?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322284

26 October 2017

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1 reference

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26 October 2017

Rifampin's acute inhibitory and chronic inductive drug interactions: experimental and model-based approaches to drug-drug interaction trial design.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322284

17 August 2018

Drug-drug interactions mediated through P-glycoprotein: clinical relevance and in vitro-in vivo correlation using digoxin as a probe drug

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322284

17 August 2018

Simultaneous binding of two different drugs in the binding pocket of the human multidrug resistance P-glycoprotein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322284

17 August 2018

Phospholipid flippase activity of the reconstituted P-glycoprotein multidrug transporter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322284

17 August 2018

Drug transport by reconstituted P-glycoprotein in proteoliposomes. Effect of substrates and modulators, and dependence on bilayer phase state

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322284

17 August 2018

Site-directed fluorescence labeling of P-glycoprotein on cysteine residues in the nucleotide binding domains

1 reference

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17 August 2018

A method for the determination of inorganic phosphate in the presence of labile organic phosphate and high concentrations of protein: application to lens ATPases

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2012.02.002

7 January 2021

Communication between multiple drug binding sites on P-glycoprotein

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2012.02.002

7 January 2021

Interaction of P-glycoprotein with defined phospholipid bilayers: a differential scanning calorimetric study

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2012.02.002

7 January 2021

Pharmacological characterization of LY335979: a potent cyclopropyldibenzosuberane modulator of P-glycoprotein

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2012.02.002

7 January 2021

Substrate- and species-dependent inhibition of P-glycoprotein-mediated transport: implications for predicting in vivo drug interactions

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2012.02.002

7 January 2021

Identifiers

10.1016/J.VASCN.2012.02.002

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

ResearchGate publication ID

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