(Q42407093)

English

Relationship between phosphorylated histone H2AX formation and cell survival in human microvascular endothelial cells (HMEC) as a function of ionizing radiation exposure in the presence or absence of thiol-containing drugs

scientific article published on July 2007

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

29 October 2017

Relationship between phosphorylated histone H2AX formation and cell survival in human microvascular endothelial cells (HMEC) as a function of ionizing radiation exposure in the presence or absence of thiol-containing drugs (English)

1 reference

Europe PubMed Central

PMC publication ID

29 October 2017

0 references

phosphorylation

0 references

4

object named as

David J Grdina

1 reference

Europe PubMed Central

PMC publication ID

29 October 2017

author name string

Yasushi Kataoka

1

1 reference

Europe PubMed Central

PMC publication ID

29 October 2017

Jeffrey S Murley

2

1 reference

Europe PubMed Central

PMC publication ID

29 October 2017

Kenneth L Baker

3

1 reference

Europe PubMed Central

PMC publication ID

29 October 2017

publication date

1 July 2007

1 reference

Europe PubMed Central

PMC publication ID

29 October 2017

Radiation Research

1 reference

Europe PubMed Central

PMC publication ID

29 October 2017

168

1 reference

Europe PubMed Central

PMC publication ID

29 October 2017

1

1 reference

Europe PubMed Central

PMC publication ID

29 October 2017

106-114

1 reference

Europe PubMed Central

PMC publication ID

29 October 2017

Flow cytometric analysis of phosphorylated histone H2AX following exposure to ionizing radiation in human microvascular endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1958995

28 May 2018

Delayed radioprotection by nuclear transcription factor kappaB -mediated induction of manganese superoxide dismutase in human microvascular endothelial cells after exposure to the free radical scavenger WR1065.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1958995

28 May 2018

Radiation induced DNA damage and damage repair in human tumor and fibroblast cell lines assessed by histone H2AX phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1958995

28 May 2018

Does gammaH2AX foci formation depend on the presence of DNA double strand breaks?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1958995

28 May 2018

Radiation sensitivity, H2AX phosphorylation, and kinetics of repair of DNA strand breaks in irradiated cervical cancer cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1958995

28 May 2018

Distribution and dynamics of chromatin modification induced by a defined DNA double-strand break

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1958995

28 May 2018

ATM and DNA-PK function redundantly to phosphorylate H2AX after exposure to ionizing radiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1958995

28 May 2018

Senescing human cells and ageing mice accumulate DNA lesions with unrepairable double-strand breaks

1 reference

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28 May 2018

Phosphorylation of histone H2AX as a measure of radiosensitivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1958995

28 May 2018

Cell Cycle-Dependent Expression of Phosphorylated Histone H2AX: Reduced Expression in Unirradiated but not X-Irradiated G1-Phase Cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1958995

28 May 2018

Evidence for a lack of DNA double-strand break repair in human cells exposed to very low x-ray doses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1958995

28 May 2018

Radioprotectants: current status and new directions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1958995

28 May 2018

Amifostine: mechanisms of action underlying cytoprotection and chemoprevention

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1958995

28 May 2018

A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1958995

28 May 2018

Cytoprotection by WR-1065, the active form of amifostine, is independent of p53 status in human malignant glioma cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1958995

28 May 2018

Megabase chromatin domains involved in DNA double-strand breaks in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1958995

28 May 2018

Chemoprotectants: a review of their clinical pharmacology and therapeutic efficacy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1958995

28 May 2018

Clinical and preclinical modulation of chemotherapy-induced toxicity in patients with cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1958995

28 May 2018

DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1958995

28 May 2018

The effect of 2-[(aminopropyl)amino] ethanethiol (WR-1065) on radiation induced DNA double strand damage and repair in V79 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1958995

28 May 2018

Radioprotection of DNA by thiols: relationship between the net charge on a thiol and its ability to protect DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1958995

28 May 2018

Radioprotection of cells in culture by WR-2721 and derivatives: form of the drug responsible for protection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1958995

28 May 2018

Radioprotection of cultured mammalian cells by the aminothiols WR-1065 and WR-255591: correlation between protection against DNA double-strand breaks and cell killing after gamma radiation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1958995

28 May 2018

Radiation protectors: the unexpected benefits

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1958995

28 May 2018

Aerobic radioprotection of pBR322 by thiols: effect of thiol net charge upon scavenging of hydroxyl radicals and repair of DNA radicals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1958995

28 May 2018

HMEC-1: establishment of an immortalized human microvascular endothelial cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1958995

28 May 2018

The radioprotector WR1065 reduces radiation-induced mutations at the hypoxanthine-guanine phosphoribosyl transferase locus in V79 cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1958995

28 May 2018

Relationship between DNA double-strand break rejoining and cell survival after exposure to ionizing radiation in human fibroblast strains with differing ATM/p53 status: implications for evaluation of clinical radiosensitivity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1958995

16 August 2018

Detection of DNA damage in individual cells by analysis of histone H2AX phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1958995

16 August 2018

The effects of antioxidants on radiation-induced apoptosis pathways in TK6 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1958995

16 August 2018

Antioxidant role of N-acetyl cysteine isomers following high dose irradiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1958995

16 August 2018

Attenuation of ischemia/reperfusion induced MAP kinases by N-acetyl cysteine, sodium nitroprusside and phosphoramidon

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1958995

16 August 2018

Multiple redox regulation of the cellular signaling system linked to AP-1 and NFkappaB: effects of N-acetylcysteine and H2O2 on the receptor tyrosine kinases, the MAP kinase cascade, and IkappaB kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1958995

16 August 2018

Quantitative detection of (125)IdU-induced DNA double-strand breaks with gamma-H2AX antibody

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1958995

16 August 2018

Prevention of radiation-induced nephropathy and fibrosis in a model of bone marrow transplant by an angiotensin II receptor blocker

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1958995

16 August 2018

Redox signaling and the emerging therapeutic potential of thiol antioxidants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1958995

16 August 2018

Control of radiation-induced pneumopathy and lung fibrosis by angiotensin-converting enzyme inhibitors and an angiotensin II type 1 receptor blocker

1 reference

https://pubmed.ncbi.nlm.nih.gov/17723002

12 December 2020

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Involvement of Ras-Regulated Myosin Light Chain Phosphorylation in the Captopril Effects in Spontaneously Hypertensive Rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/17723002

12 December 2020

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Inactivation of a redox-sensitive protein phosphatase during the early events of tumor necrosis factor/interleukin-1 signal transduction

1 reference

https://pubmed.ncbi.nlm.nih.gov/17723002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ifosfamide induced stress response in human lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17723002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protection against radiation-induced mutagenesis at the hprt locus by spermine and N,N"-(dithiodi-2,1-ethanediyl)bis-1,3-propanediamine (WR-33278)

1 reference

https://pubmed.ncbi.nlm.nih.gov/17723002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Captopril inhibits pp60(c-src) tyrosine phosphorylation in cultured human mesangial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17723002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

WR-1065, an active metabolite of the cytoprotector amifostine, affects phosphorylation of topoisomerase II alpha leading to changes in enzyme activity and cell cycle progression in CHO AA8 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17723002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential antimutagenicity of WR-1065 added after irradiation in L5178Y cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/17723002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1667/RR0975.1

1 reference

Europe PubMed Central

PMC publication ID

29 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

29 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

29 October 2017

ResearchGate publication ID

0 references

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