(Q42414110)

English

The membrane targeted apoptosis modulators erucylphosphocholine and erucylphosphohomocholine increase the radiation response of human glioblastoma cell lines in vitro

scientific article published on 29 March 2006

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scholarly article

1 reference

Europe PubMed Central

30 October 2017

The membrane targeted apoptosis modulators erucylphosphocholine and erucylphosphohomocholine increase the radiation response of human glioblastoma cell lines in vitro (English)

1 reference

Europe PubMed Central

30 October 2017

1 reference

based on heuristic

inferred from title

3

1 reference

Europe PubMed Central

30 October 2017

7

object named as

Claus Belka

1 reference

Europe PubMed Central

30 October 2017

author name string

Amelie Rübel

1

1 reference

Europe PubMed Central

30 October 2017

René Handrick

2

1 reference

Europe PubMed Central

30 October 2017

Matthias Steiger

4

1 reference

Europe PubMed Central

30 October 2017

Hansjörg Eibl

5

1 reference

Europe PubMed Central

30 October 2017

Wilfried Budach

6

1 reference

Europe PubMed Central

30 October 2017

Verena Jendrossek

8

1 reference

Europe PubMed Central

30 October 2017

publication date

29 March 2006

1 reference

Europe PubMed Central

30 October 2017

Radiation Oncology

1 reference

Europe PubMed Central

30 October 2017

1

1 reference

Europe PubMed Central

30 October 2017

6

1 reference

Europe PubMed Central

30 October 2017

https://scigraph.springernature.com/pub.10.1186/1748-717x-1-6

0 references

Phase II study of perifosine in previously untreated patients with metastatic melanoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1475859

28 May 2018

Irradiation specifically sensitises solid tumour cell lines to TRAIL mediated apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1475859

28 May 2018

Apoptosis-modulating agents in combination with radiotherapy-current status and outlook

1 reference

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28 May 2018

Stress-induced apoptosis: toward a symmetry with receptor-mediated cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1475859

28 May 2018

Radiation and ceramide-induced apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1475859

28 May 2018

Membrane targeted anticancer drugs: potent inducers of apoptosis and putative radiosensitisers

1 reference

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28 May 2018

Anti-epidermal growth factor receptor strategies to enhance radiation action

1 reference

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28 May 2018

Disruption of cell death signaling in cancer: impact on disease prognosis and response to therapy

1 reference

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28 May 2018

Oral miltefosine for Indian visceral leishmaniasis

1 reference

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28 May 2018

The Bcl2 family: regulators of the cellular life-or-death switch

1 reference

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28 May 2018

Anti-apoptotic Bcl-2 proteins: structure, function and relevance for radiation biology

1 reference

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28 May 2018

Live or let die: the cell's response to p53

1 reference

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28 May 2018

Ceramide induces mitochondrial activation and apoptosis via a Bax-dependent pathway in human carcinoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1475859

28 May 2018

Erucylphosphocholine-induced apoptosis in chemoresistant glioblastoma cell lines: involvement of caspase activation and mitochondrial alterations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1475859

28 May 2018

The phosphatidylinositide 3'-kinase/Akt survival pathway is a target for the anticancer and radiosensitizing agent PKC412, an inhibitor of protein kinase C.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1475859

28 May 2018

Randomized, double-blind, placebo-controlled, multicenter trial of 6% miltefosine solution, a topical chemotherapy in cutaneous metastases from breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1475859

28 May 2018

PUMA, a novel proapoptotic gene, is induced by p53

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1475859

28 May 2018

Malignant glioma: genetics and biology of a grave matter.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1475859

28 May 2018

Alkyl-lysophospholipids as anticancer agents and enhancers of radiation-induced apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1475859

28 May 2018

Phase II study of miltefosine 6% solution as topical treatment of skin metastases in breast cancer patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1475859

28 May 2018

Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1475859

28 May 2018

Treatment of patients with primary glioblastoma multiforme with standard postoperative radiotherapy and radiosurgical boost: prognostic factors and long-term outcome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1475859

28 May 2018

Alkyl-lysophospholipids activate the SAPK/JNK pathway and enhance radiation-induced apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1475859

28 May 2018

Apoptosis, p53, and tumor cell sensitivity to anticancer agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1475859

28 May 2018

Erucylphosphocholine, a novel antineoplastic ether lipid, blocks growth and induces apoptosis in brain tumor cell lines in vitro.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1475859

28 May 2018

Protein kinase B (PKB/Akt) activity is elevated in glioblastoma cells due to mutation of the tumor suppressor PTEN/MMAC.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1475859

28 May 2018

PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1475859

28 May 2018

Thermoradiotherapy for brain tumors. Three cases of recurrent malignant astrocytoma and review of clinical experience

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1475859

28 May 2018

p53 is required for radiation-induced apoptosis in mouse thymocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1475859

28 May 2018

Evidence for abrogation of oncogene-induced radioresistance of mammary cancer cells by hexadecylphosphocholine in vitro.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1475859

28 May 2018

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1475859

28 May 2018

Phospholipid antitumor agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1475859

28 May 2018

Hexadecylphosphocholine in the topical treatment of skin metastases in breast cancer patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1475859

28 May 2018

A Method for Testing for Synergy with Any Number of Agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1475859

28 May 2018

A phase II study of perifosine in androgen independent prostate cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1475859

16 August 2018

A phase I trial of perifosine (NSC 639966) on a loading dose/maintenance dose schedule in patients with advanced cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1475859

16 August 2018

Intracellular mediators of erucylphosphocholine-induced apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1475859

16 August 2018

Increased delivery of erucylphosphocholine to C6 gliomas by chemical opening of the blood-brain barrier using intracarotid pentylglycerol in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1475859

16 August 2018

Phase I and pharmacological study of daily oral administration of perifosine (D-21266) in patients with advanced solid tumours

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1475859

16 August 2018

Structure-activity relationships of alkylphosphocholine derivatives: antineoplastic action on brain tumor cell lines in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1475859

16 August 2018

Combination effects of alkylphosphocholines and gemcitabine in malignant and normal hematopoietic cells

1 reference

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Cancer surveillance series [corrected]: brain and other central nervous system cancers: recent trends in incidence and mortality.

1 reference

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16 August 2018

Meta-analysis of radiation therapy with and without adjuvant chemotherapy for malignant gliomas in adults.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1475859

16 August 2018

Topical administration of hexadecylphosphocholine in patients with cutaneous lymphomas: results of a phase I/II study

1 reference

https://pubmed.ncbi.nlm.nih.gov/16722524

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Miltefosine as a topical treatment for cutaneous metastases in breast carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/16722524

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fate of 1-O-octadecyl-2-O-methyl-rac-glycero-3-phosphocholine (ET18-OME) in malignant cells, normal cells, and isolated and perfused rat liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/16722524

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Opposite effect of miltefosine on the antineoplastic activity and haematological toxicity of cyclophosphamide

1 reference

https://pubmed.ncbi.nlm.nih.gov/16722524

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Erucylphosphocholine: pharmacokinetics, biodistribution and CNS-accumulation in the rat after intravenous administration

1 reference

https://pubmed.ncbi.nlm.nih.gov/16722524

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human urinary bladder carcinoma cell lines respond to treatment with alkylphosphocholines

1 reference

https://pubmed.ncbi.nlm.nih.gov/16722524

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

D-21266, a new heterocyclic alkylphospholipid with antitumour activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/16722524

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synergistic cytotoxic effects of ether phospholipid analogues and ionizing radiation in human carcinoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16722524

12 December 2020

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Sensitization of resistant lymphoma cells to irradiation-induced apoptosis by the death ligand TRAIL

1 reference

https://pubmed.ncbi.nlm.nih.gov/16722524

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/1748-717X-1-6

1 reference

Europe PubMed Central

30 October 2017

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1 reference

Europe PubMed Central

30 October 2017

1 reference

Europe PubMed Central

30 October 2017

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