(Q42443427)

English

Overexpression of interferon-gamma-inducible GTPase inhibits coxsackievirus B3-induced apoptosis through the activation of the phosphatidylinositol 3-kinase/Akt pathway and inhibition of viral replication.

scientific article published on 20 June 2003

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5 November 2019

Overexpression of interferon-gamma-inducible GTPase inhibits coxsackievirus B3-induced apoptosis through the activation of the phosphatidylinositol 3-kinase/Akt pathway and inhibition of viral replication (English)

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Huifang M Zhang

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Ji Yuan

2

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Paul Cheung

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Honglin Luo

4

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Bobby Yanagawa

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David Chau

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Najwan Stephan-Tozy

7

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Jingchun Zhang

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Janet E Wilson

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Bruce M McManus

11

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Decheng Yang

12

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20 June 2003

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Journal of Biological Chemistry

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278

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33011-33019

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5 November 2019

How cells respond to interferons

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305352200

21 January 2018

Cellular responses to interferon-gamma

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305352200

21 January 2018

Identification of a novel GTPase, the inducibly expressed GTPase, that accumulates in response to interferon gamma

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305352200

21 January 2018

Pathogen-specific loss of host resistance in mice lacking the IFN-gamma-inducible gene IGTP

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305352200

21 January 2018

A monomeric GTPase-negative MxA mutant with antiviral activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305352200

21 January 2018

Gamma interferon-induced inhibition of Toxoplasma gondii in astrocytes is mediated by IGTP.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305352200

21 January 2018

Inactivation of LRG-47 and IRG-47 reveals a family of interferon gamma-inducible genes with essential, pathogen-specific roles in resistance to infection

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305352200

21 January 2018

The inducibly expressed GTPase localizes to the endoplasmic reticulum, independently of GTP binding

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305352200

21 January 2018

Viral myocarditis: identification of five differentially expressed genes in coxsackievirus B3-infected mouse heart.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305352200

21 January 2018

Phosphatidylinositol-3-OH kinase as a direct target of Ras

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305352200

21 January 2018

A permissive function of phosphoinositide 3-kinase in Ras activation mediated by inhibition of GTPase-activating proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305352200

21 January 2018

Coxsackievirus B3 replication is reduced by inhibition of the extracellular signal-regulated kinase (ERK) signaling pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305352200

21 January 2018

Eukaryotic translation initiation factor 4G is targeted for proteolytic cleavage by caspase 3 during inhibition of translation in apoptotic cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305352200

21 January 2018

Poliovirus protease 3C(pro) kills cells by apoptosis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305352200

21 January 2018

Poliovirus 2A protease induces apoptotic cell death

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305352200

21 January 2018

Phosphoinositide kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305352200

21 January 2018

Structure and function of phosphoinositide 3-kinases.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305352200

21 January 2018

Role of translocation in the activation and function of protein kinase B

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305352200

21 January 2018

PKB/AKT: functional insights from genetic models

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305352200

21 January 2018

Ten years of protein kinase B signalling: a hard Akt to follow

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305352200

21 January 2018

Roles of phosphatidylinositol 3-kinase in interferon-gamma-dependent phosphorylation of STAT1 on serine 727 and activation of gene expression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305352200

21 January 2018

Regulation of cell death protease caspase-9 by phosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305352200

21 January 2018

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305352200

21 January 2018

Macrophage colony-stimulating factor promotes cell survival through Akt/protein kinase B.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305352200

21 January 2018

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305352200

21 January 2018

Nip21 gene expression reduces coxsackievirus B3 replication by promoting apoptotic cell death via a mitochondria-dependent pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305352200

21 January 2018

Caspase-dependent cleavage of signaling proteins during apoptosis. A turn-off mechanism for anti-apoptotic signals

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305352200

21 January 2018

Cleavage and inactivation of antiapoptotic Akt/PKB by caspases during apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305352200

21 January 2018

Role of PI 3-kinase, Akt and Bcl-2-related proteins in sustaining the survival of neurotrophic factor-independent adult sympathetic neurons

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305352200

21 January 2018

PI3K: downstream AKTion blocks apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305352200

21 January 2018

Mechanisms and consequences of activation of protein kinase B/Akt

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305352200

21 January 2018

Activation of the phosphatidylinositol 3-kinase/Akt signaling pathway by retinoic acid is required for neural differentiation of SH-SY5Y human neuroblastoma cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305352200

21 January 2018

Insulin-like growth factor I prevents mannitol-induced degradation of focal adhesion kinase and Akt.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305352200

21 January 2018

NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305352200

21 January 2018

Expression of constitutively active phosphatidylinositol 3-kinase inhibits activation of caspase 3 and apoptosis of cardiac muscle cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305352200

21 January 2018

The hepatitis B virus-X protein activates a phosphatidylinositol 3-kinase-dependent survival signaling cascade

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305352200

21 January 2018

Akt mediates cytoprotection of endothelial cells by vascular endothelial growth factor in an anchorage-dependent manner

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305352200

21 January 2018

Biochemical pathways of caspase activation during apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305352200

21 January 2018

Translational control in mammalian cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305352200

21 January 2018

Caspases are not involved in the cleavage of translation initiation factor eIF4GI during picornavirus infection

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305352200

21 January 2018

A Bad kinase makes good

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305352200

21 January 2018

The tyrosine kinase p56lck is essential in coxsackievirus B3-mediated heart disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305352200

21 January 2018

Host gene regulation during coxsackievirus B3 infection in mice: assessment by microarrays

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305352200

21 January 2018

PtdIns(3,4,5)P3 gets its message across

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305352200

21 January 2018

Identifiers

10.1074/JBC.M305352200

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Europe PubMed Central

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5 November 2019

1 reference

Europe PubMed Central

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5 November 2019

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