(Q42452880)

English

Signalling pathways influencing basal and H2O2‐induced P‐glycoprotein expression in endothelial cells derived from the blood–brain barrier

scientific article published on November 1, 2003

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scholarly article

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Europe PubMed Central

PubMed publication ID

31 October 2017

Signalling pathways influencing basal and H(2)O(2)-induced P-glycoprotein expression in endothelial cells derived from the blood-brain barrier (English)

1 reference

Europe PubMed Central

PubMed publication ID

31 October 2017

Signalling pathways influencing basal and H2O2‐induced P‐glycoprotein expression in endothelial cells derived from the blood–brain barrier (English)

1 reference

10.1046/J.1471-4159.2003.02061.X

https://api.crossref.org/works/10.1046/J.1471-4159.2003.02061.X

2 April 2024

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blood–brain barrier

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based on heuristic

inferred from title

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10.1046/J.1471-4159.2003.02061.X

https://api.crossref.org/works/10.1046/J.1471-4159.2003.02061.X

2 April 2024

author name string

Osi M. Nwaozuzu

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14622133

2 April 2024

Lynda A. Sellers

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14622133

2 April 2024

Margery A. Barrand

3

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2 April 2024

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1 November 2003

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31 October 2017

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https://onlinelibrary.wiley.com/doi/pdfdirect/10.1046/j.1471-4159.2003.02061.x

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14622133

2 April 2024

https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1046%2Fj.1471-4159.2003.02061.x

1 reference

10.1046/J.1471-4159.2003.02061.X

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2 April 2024

https://onlinelibrary.wiley.com/doi/pdf/10.1046/j.1471-4159.2003.02061.x

1 reference

10.1046/J.1471-4159.2003.02061.X

https://api.crossref.org/works/10.1046/J.1471-4159.2003.02061.X

2 April 2024

Journal of Neurochemistry

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31 October 2017

87

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Europe PubMed Central

PubMed publication ID

31 October 2017

4

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Europe PubMed Central

PubMed publication ID

31 October 2017

1043-1051

1 reference

Europe PubMed Central

PubMed publication ID

31 October 2017

Hydrogen peroxide activates mitogen-activated protein kinases and Na+-H+ exchange in neonatal rat cardiac myocytes

1 reference

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The cellular response to oxidative stress: influences of mitogen-activated protein kinase signalling pathways on cell survival

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Astrocyte-endothelial interactions and blood-brain barrier permeability

1

1 reference

10.1046/J.1471-4159.2003.02061.X

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Comparisons of P‐glycoprotein expression in isolated rat brain microvessels and in primary cultures of endothelial cells derived from microvasculature of rat brain, epididymal fat pad and from aorta

3

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Involvement of regulatory and catalytic subunits of phosphoinositide 3-kinase in NF-kappaB activation.

4

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Oxidative stress and nuclear factor-kappaB activation: a reassessment of the evidence in the light of recent discoveries.

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c-Jun N-terminal kinase activation by hydrogen peroxide in endothelial cells involves SRC-dependent epidermal growth factor receptor transactivation

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Reactive oxygen species as downstream mediators of angiogenic signaling by vascular endothelial growth factor receptor-2/KDR.

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2-acetylaminofluorene up-regulates rat mdr1b expression through generating reactive oxygen species that activate NF-kappa B pathway

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2 April 2024

P-glycoprotein expression in rat brain endothelial cells: evidence for regulation by transient oxidative stress.

9

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Tumor necrosis factor and reactive oxygen species cooperative cytotoxicity is mediated via inhibition of NF-kappaB.

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NF-kappa B is activated and ICAM-1 gene expression is upregulated during reoxygenation of human brain endothelial cells

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PECAM-1 (CD31) regulates a hydrogen peroxide-activated nonselective cation channel in endothelial cells

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H(2)O(2)-mediated permeability II: importance of tyrosine phosphatase and kinase activity

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Cytokine-induced activation of nuclear factor-kappa B is inhibited by hydrogen peroxide through oxidative inactivation of IkappaB kinase

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Induction of human MDR1 gene expression by 2-acetylaminofluorene is mediated by effectors of the phosphoinositide 3-kinase pathway that activate NF-kappaB signaling

16

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H2O2 and tumor necrosis factor-alpha induce differential binding of the redox-responsive transcription factors AP-1 and NF-kappaB to the interleukin-8 promoter in endothelial and epithelial cells

17

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beta-Amyloid efflux mediated by p-glycoprotein

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Inhibition of nuclear translocation of transcription factor NF-kappa B by a synthetic peptide containing a cell membrane-permeable motif and nuclear localization sequence

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Superfolding of the partially unfolded core-glycosylated intermediate of human P-glycoprotein into the mature enzyme is promoted by substrate-induced transmembrane domain interactions.

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Differential regulation of extracellular signal-regulated kinase and nuclear factor-kappa B signal transduction pathways by hydrogen peroxide and tumor necrosis factor

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PKB/AKT: functional insights from genetic models

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P-Glycoprotein, a gatekeeper in the blood-brain barrier

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Multidrug resistance-related transport proteins in isolated human brain microvessels and in cells cultured from these isolates.

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The drug efflux protein, P-glycoprotein, additionally protects drug-resistant tumor cells from multiple forms of caspase-dependent apoptosis

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Regulation of the multidrug resistance genes by stress signals

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Up-regulation of multidrug resistance P-glycoprotein via nuclear factor-kappaB activation protects kidney proximal tubule cells from cadmium- and reactive oxygen species-induced apoptosis

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Deposition of Alzheimer's beta-amyloid is inversely correlated with P-glycoprotein expression in the brains of elderly non-demented humans.

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Endothelial preconditioning by transient oxidative stress reduces inflammatory responses of cultured endothelial cells to TNF-alpha

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Reactive oxygen species participate in mdr1b mRNA and P-glycoprotein overexpression in primary rat hepatocyte cultures.

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Identifiers

10.1046/J.1471-4159.2003.02061.X

1 reference

Europe PubMed Central

PubMed publication ID

31 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 October 2017

ResearchGate publication ID

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