(Q42486578)

English

Neurological and neurodegenerative alterations in a transgenic mouse model expressing human alpha-synuclein under oligodendrocyte promoter: implications for multiple system atrophy.

scientific article published on November 2005

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16291942%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Neurological and neurodegenerative alterations in a transgenic mouse model expressing human alpha-synuclein under oligodendrocyte promoter: implications for multiple system atrophy (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16291942%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

oligodendrocyte

1 reference

based on heuristic

inferred from title

neurodegeneration

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16291942%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Eliezer Masliah

11

object named as

Eliezer Masliah

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16291942%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

author name string

Clifford W Shults

1

1 reference

Europe PubMed Central

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9 January 2020

Anthony Adame

4

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16291942%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Michael Mante

5

1 reference

Europe PubMed Central

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9 January 2020

Gabriel Larrea

6

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16291942%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Makoto Hashimoto

7

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16291942%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

David Song

8

1 reference

Europe PubMed Central

PMC publication ID

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9 January 2020

Takeshi Iwatsubo

9

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16291942%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Kyoko Tsuboi

10

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16291942%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Edward Rockenstein

2

1 reference

Europe PubMed Central

PMC publication ID

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9 January 2020

language of work or name

0 references

publication date

1 November 2005

1 reference

Europe PubMed Central

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9 January 2020

Journal of Neuroscience

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16291942%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

25

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Europe PubMed Central

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9 January 2020

46

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16291942%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

10689-10699

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16291942%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6725840/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Evolution of amyloid: what normal protein folding may tell us about fibrillogenesis and disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fatal attractions: abnormal protein aggregation and neuron death in Parkinson's disease and Lewy body dementia

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative stress induces amyloid-like aggregate formation of NACP/alpha-synuclein in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Consensus statement on the diagnosis of multiple system atrophy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alpha-synuclein in Lewy body disease and Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple system atrophy: a sporadic synucleinopathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alpha-synuclein immunoisolation of glial inclusions from multiple system atrophy brain tissue reveals multiprotein components

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A Drosophila model of Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synucleins are developmentally expressed, and alpha-synuclein regulates the size of the presynaptic vesicular pool in primary hippocampal neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Constant involvement of the Betz cells and pyramidal tract in multiple system atrophy: a clinicopathological study of seven autopsy cases

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Is there a cause-and-effect relationship between alpha-synuclein fibrillization and Parkinson's disease?

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Properties of NACP/alpha-synuclein and its role in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurodegeneration with brain iron accumulation, type 1 is characterized by alpha-, beta-, and gamma-synuclein neuropathology

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuropathology in mice expressing human alpha-synuclein

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

alpha-synuclein is developmentally expressed in cultured rat brain oligodendrocytes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunohistochemical and biochemical studies demonstrate a distinct profile of alpha-synuclein permutations in multiple system atrophy

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronic systemic pesticide exposure reproduces features of Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced neuritic outgrowth and cell adhesion in neuronal cells transfected with human alpha-synuclein

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alpha-synuclein and Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurofibrillary pathology in transgenic mice overexpressing V717F beta-amyloid precursor protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alpha-synuclein and neurodegenerative diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alpha-synuclein and the Lewy body disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glial cell death induced by overexpression of alpha-synuclein

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

beta-amyloid peptides enhance alpha-synuclein accumulation and neuronal deficits in a transgenic mouse model linking Alzheimer's disease and Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Behavioral phenotyping of the MPTP mouse model of Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The herbicide paraquat causes up-regulation and aggregation of alpha-synuclein in mice: paraquat and alpha-synuclein

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple system atrophy: cellular and molecular pathology

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective insolubility of alpha-synuclein in human Lewy body diseases is recapitulated in a transgenic mouse model

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early formation of mature amyloid-beta protein deposits in a mutant APP transgenic model depends on levels of Abeta(1-42).

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

alpha-Synuclein is phosphorylated in synucleinopathy lesions

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Patterns of protein nitration in dementia with Lewy bodies and striatonigral degeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Animal models of Parkinson's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hyperphosphorylation and insolubility of alpha-synuclein in transgenic mouse oligodendrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuronal alpha-synucleinopathy with severe movement disorder in mice expressing A53T human alpha-synuclein.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human alpha-synuclein-harboring familial Parkinson's disease-linked Ala-53 --> Thr mutation causes neurodegenerative disease with alpha-synuclein aggregation in transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential neuropathological alterations in transgenic mice expressing alpha-synuclein from the platelet-derived growth factor and Thy-1 promoters

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oligodendrocytes from neural stem cells express alpha-synuclein: increased numbers from presenilin 1 deficient mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MPTP: insights into parkinsonian neurodegeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mice expressing the alpha(1B)-adrenergic receptor induces a synucleinopathy with excessive tyrosine nitration but decreased phosphorylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative stress and nitration in neurodegeneration: cause, effect, or association?

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Motor behaviour deficits and their histopathological and functional correlates in the nigrostriatal system of dopamine transporter knockout mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondria, oxidative damage, and inflammation in Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Myelin basic protein gene contains separate enhancers for oligodendrocyte and Schwann cell expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

alpha-Synuclein locus triplication causes Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhanced substantia nigra mitochondrial pathology in human alpha-synuclein transgenic mice after treatment with MPTP.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An antiaggregation gene therapy strategy for Lewy body disease utilizing beta-synuclein lentivirus in a transgenic model

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early and progressive sensorimotor anomalies in mice overexpressing wild-type human alpha-synuclein.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cognitive performance in multiple system atrophy

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of alpha-synuclein in the pathogenesis of multiple system atrophy

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative stress in transgenic mice with oligodendroglial alpha-synuclein overexpression replicates the characteristic neuropathology of multiple system atrophy

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mouse model of multiple system atrophy alpha-synuclein expression in oligodendrocytes causes glial and neuronal degeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alpha-synuclein overexpression in oligodendrocytic cells results in impaired adhesion to fibronectin and cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An autopsy case of early ("minimal change") olivopontocerebellar atrophy (multiple system atrophy-cerebellar).

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MPTP-induced parkinsonian model in mice: biochemistry, pharmacology and behavior.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A simple quantitative bradykinesia test in MPTP-treated mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Orthostatic hypotension and nicotine sensitivity in a case of multiple system atrophy

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Levels and alternative splicing of amyloid beta protein precursor (APP) transcripts in brains of APP transgenic mice and humans with Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The precursor protein of non-A beta component of Alzheimer's disease amyloid is a presynaptic protein of the central nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Central nervous system damage produced by expression of the HIV-1 coat protein gp120 in transgenic mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular pathology of multiple system atrophy: a review

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered presynaptic protein NACP is associated with plaque formation and neurodegeneration in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Attentional functions in multiple system atrophy and Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pole test is a useful method for evaluating the mouse movement disorder caused by striatal dopamine depletion.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alpha-synuclein in Lewy bodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abnormal accumulation of NACP/alpha-synuclein in neurodegenerative disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NACP, a presynaptic protein, immunoreactivity in Lewy bodies in Parkinson's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The synucleins: a family of proteins involved in synaptic function, plasticity, neurodegeneration and disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human recombinant NACP/alpha-synuclein is aggregated and fibrillated in vitro: relevance for Lewy body disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alpha-synuclein immunoreactivity in glial cytoplasmic inclusions in multiple system atrophy

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Filamentous alpha-synuclein inclusions link multiple system atrophy with Parkinson's disease and dementia with Lewy bodies.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell death mechanisms in multiple system atrophy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Accumulation of alpha-synuclein/NACP is a cytopathological feature common to Lewy body disease and multiple system atrophy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The definition of multiple system atrophy: a review of recent developments

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.3527-05.2005

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16291942%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16291942%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16291942%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

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