(Q42520141)

1 November 2017

title

The NEDD8 pathway is essential for SCF(beta -TrCP)-mediated ubiquitination and processing of the NF-kappa B precursor p105. (English)

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1 November 2017

main subject

protein ubiquitination

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3

Aaron Ciechanover

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1 November 2017

Ruthie E Amir

1

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1 November 2017

Kazuhiro Iwai

series ordinal

2

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1 November 2017

language of work or name

English

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publication date

12 April 2002

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Journal of Biological Chemistry

1 November 2017

published in

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1 November 2017

volume

277

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1 November 2017

issue

26

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1 November 2017

page(s)

23253-23259

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NF-kappaB to the rescue: RELs, apoptosis and cellular transformation

1 November 2017

cites work

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A glycine-rich region in NF-kappaB p105 functions as a processing signal for the generation of the p50 subunit

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NF-kappaB p105 is a target of IkappaB kinases and controls signal induction of Bcl-3-p50 complexes

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SCF(beta)(-TrCP) ubiquitin ligase-mediated processing of NF-kappaB p105 requires phosphorylation of its C-terminus by IkappaB kinase

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Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity

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Modes of regulation of ubiquitin-mediated protein degradation

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CHIP is a U-box-dependent E3 ubiquitin ligase: identification of Hsc70 as a target for ubiquitylation

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A novel class of herpesvirus-encoded membrane-bound E3 ubiquitin ligases regulates endocytosis of proteins involved in immune recognition

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SCF and Cullin/Ring H2-based ubiquitin ligases

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The ankyrin repeat domains of the NF-kappa B precursor p105 and the protooncogene bcl-3 act as specific inhibitors of NF-kappa B DNA binding

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The precursor of NF-kappa B p50 has I kappa B-like functions

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Autoregulation of the NF-kappa B transactivator RelA (p65) by multiple cytoplasmic inhibitors containing ankyrin motifs

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Processing of p105 is inhibited by docking of p50 active subunits to the ankyrin repeat domain, and inhibition is alleviated by signaling via the carboxyl-terminal phosphorylation/ ubiquitin-ligase binding domain

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A new NEDD8-ligating system for cullin-4A

21 January 2018

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Identification of the activating and conjugating enzymes of the NEDD8 conjugation pathway

21 January 2018

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An E3-like factor that promotes SUMO conjugation to the yeast septins

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Identification of the von Hippel-lindau tumor-suppressor protein as part of an active E3 ubiquitin ligase complex

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Covalent modifier NEDD8 is essential for SCF ubiquitin-ligase in fission yeast

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Modification of yeast Cdc53p by the ubiquitin-related protein rub1p affects function of the SCFCdc4 complex

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The NEDD8 system is essential for cell cycle progression and morphogenetic pathway in mice

21 January 2018

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Conjugation of Nedd8 to CUL1 enhances the ability of the ROC1-CUL1 complex to promote ubiquitin polymerization

21 January 2018

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Nedd8 modification of cul-1 activates SCF(beta(TrCP))-dependent ubiquitination of IkappaBalpha

21 January 2018

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Modification of cullin-1 by ubiquitin-like protein Nedd8 enhances the activity of SCF(skp2) toward p27(kip1).

21 January 2018

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A Nedd8 conjugation pathway is essential for proteolytic targeting of p27Kip1 by ubiquitination

21 January 2018

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NEDD8 recruits E2-ubiquitin to SCF E3 ligase.

21 January 2018

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The Nedd8-conjugated ROC1-CUL1 core ubiquitin ligase utilizes Nedd8 charged surface residues for efficient polyubiquitin chain assembly catalyzed by Cdc34

21 January 2018

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IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation

21 January 2018

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21 January 2018

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

21 January 2018

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A dominant-negative UBC12 mutant sequesters NEDD8 and inhibits NEDD8 conjugation in vivo

21 January 2018

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Promotion of NEDD-CUL1 conjugate cleavage by COP9 signalosome

21 January 2018

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Identification of a novel isopeptidase with dual specificity for ubiquitin- and NEDD8-conjugated proteins

21 January 2018

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Targeting of NEDD8 and its conjugates for proteasomal degradation by NUB1

21 January 2018

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Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathway

21 January 2018

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NF-kappaB-inducing kinase regulates the processing of NF-kappaB2 p100

21 January 2018

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Identification of the ubiquitin carrier proteins, E2s, involved in signal-induced conjugation and subsequent degradation of IkappaBalpha

21 January 2018

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Interactions of the COP9 Signalosome with the E3 Ubiquitin Ligase SCFTIR1 in Mediating Auxin Response

21 January 2018

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Growth hormone effects on RNA and protein synthesis in liver

21 January 2018

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M200967200

Requirements for iron-regulated degradation of the RNA binding protein, iron regulatory protein 2

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M200967200

Identifiers

DOI

10.1074/JBC.M200967200

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1 November 2017

1 reference