(Q42597215)

3 November 2017

title

Synthetic sickness or lethality points at candidate combination therapy targets in glioblastoma (English)

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3 November 2017

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3 November 2017

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Martin Vingron

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3 November 2017

Navodit Misra

2

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3 November 2017

language of work or name

English

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publication date

4 June 2013

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International Journal of Cancer

3 November 2017

number of pages

10

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based on heuristic

inferred from page(s)

published in

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3 November 2017

volume

133

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3 November 2017

issue

9

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3 November 2017

page(s)

2123-2132

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Cardiotoxicity of kinase inhibitors: the prediction and translation of preclinical models to clinical outcomes.

3 November 2017

cites work

1 reference

Resistance to Targeted Therapies: Refining Anticancer Therapy in the Era of Molecular Oncology

21 January 2018

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The concept of synthetic lethality in the context of anticancer therapy

21 January 2018

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Harnessing synthetic lethal interactions in anticancer drug discovery

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The genetic landscape of a cell

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A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene

21 January 2018

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Identification of novel synergistic targets for rational drug combinations with PI3 kinase inhibitors using siRNA synthetic lethality screening against GBM.

21 January 2018

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DNA repair and synthetic lethality

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Targeting Synthetic Lethality in DNA Damage Repair Pathways as an Anti-Cancer Strategy

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Finding friends and enemies in an enemies-only network: a graph diffusion kernel for predicting novel genetic interactions and co-complex membership from yeast genetic interactions

21 January 2018

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Mining protein networks for synthetic genetic interactions

21 January 2018

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An Integrative Multi-Network and Multi-Classifier Approach to Predict Genetic Interactions

21 January 2018

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Combining biological networks to predict genetic interactions

21 January 2018

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Systematic mapping of genetic interaction networks

21 January 2018

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Learning genetic epistasis using Bayesian network scoring criteria

21 January 2018

1 reference

Detecting epistatic effects in association studies at a genomic level based on an ensemble approach

21 January 2018

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Epistasis detection on quantitative phenotypes by exhaustive enumeration using GPUs

21 January 2018

1 reference

Human synthetic lethal inference as potential anti-cancer target gene detection

21 January 2018

1 reference

Exploring genetic interactions and networks with yeast

21 January 2018

1 reference

Mutual exclusivity analysis identifies oncogenic network modules

21 January 2018

1 reference

Somatic mutations affect key pathways in lung adenocarcinoma

21 January 2018

1 reference

Correlation of somatic mutation and expression identifies genes important in human glioblastoma progression and survival

21 January 2018

1 reference

Discovering functional modules by identifying recurrent and mutually exclusive mutational patterns in tumors

21 January 2018

1 reference

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

21 January 2018

1 reference

Assessing the significance of chromosomal aberrations in cancer: methodology and application to glioma

21 January 2018

1 reference

Nonparametric Estimation from Incomplete Observations

21 January 2018

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The standard error of an estimate of expectation of life, with special reference to expectation of tumourless life in experiments with mice

21 January 2018

1 reference

A panel of isogenic human cancer cells suggests a therapeutic approach for cancers with inactivated p53

21 January 2018

1 reference

Induction of in vivo synthetic lethal RNAi responses to treat glioblastoma

21 January 2018

1 reference

Hazard ratio in clinical trials

21 January 2018

1 reference

Age-dependent prognostic effects of genetic alterations in glioblastoma

21 January 2018

1 reference

The use of restricted mean survival time to estimate the treatment effect in randomized clinical trials when the proportional hazards assumption is in doubt

21 January 2018

1 reference

De novo discovery of mutated driver pathways in cancer

21 January 2018

1 reference

Algorithms for detecting significantly mutated pathways in cancer.

21 January 2018

1 reference

Analysis of Survival Data under the Proportional Hazards Model

21 January 2018

1 reference

Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer

21 January 2018

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/citations/10.1038/NATURE11156

Identifiers

DOI

10.1002/IJC.28235

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3 November 2017

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