(Q42712289)

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Different pathways of constitutive androstane receptor-mediated liver hypertrophy and hepatocarcinogenesis in mice treated with piperonyl butoxide or decabromodiphenyl ether.

scientific article published on 26 March 2013

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23531792%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

Different pathways of constitutive androstane receptor-mediated liver hypertrophy and hepatocarcinogenesis in mice treated with piperonyl butoxide or decabromodiphenyl ether (English)

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27 February 2020

Yoshikazu Taketa

4

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27 February 2020

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Yohei Sakamoto

1

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27 February 2020

Kaoru Inoue

2

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27 February 2020

Miwa Takahashi

3

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27 February 2020

Yukio Kodama

5

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27 February 2020

Kiyomitsu Nemoto

6

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27 February 2020

Masakuni Degawa

7

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27 February 2020

Toshie Gamou

8

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27 February 2020

Shogo Ozawa

9

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27 February 2020

Akiyoshi Nishikawa

10

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27 February 2020

Midori Yoshida

11

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27 February 2020

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26 March 2013

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27 February 2020

Toxicologic Pathology

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27 February 2020

41

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27 February 2020

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27 February 2020

1078-1092

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27 February 2020

Interactions between hepatic Mrp4 and Sult2a as revealed by the constitutive androstane receptor and Mrp4 knockout mice

1 reference

https://api.crossref.org/works/10.1177%2F0192623313482055

21 January 2018

Reduction in cytochrome P-450 enzyme expression is associated with repression of CAR (constitutive androstane receptor) and PXR (pregnane X receptor) in mouse liver during the acute phase response

1 reference

https://api.crossref.org/works/10.1177%2F0192623313482055

21 January 2018

C-Myc and its target FoxM1 are critical downstream effectors of constitutive androstane receptor (CAR) mediated direct liver hyperplasia

1 reference

https://api.crossref.org/works/10.1177%2F0192623313482055

21 January 2018

Human constitutive androstane receptor mediated methotrexate induction of human dehydroepiandrosterone sulfotransferase (hSULT2A1).

1 reference

https://api.crossref.org/works/10.1177%2F0192623313482055

21 January 2018

Evaluating the human relevance of chemically induced animal tumors

1 reference

https://api.crossref.org/works/10.1177%2F0192623313482055

21 January 2018

The human relevance of information on carcinogenic modes of action: overview

1 reference

https://api.crossref.org/works/10.1177%2F0192623313482055

21 January 2018

Mode of action analysis for the synthetic pyrethroid metofluthrin-induced rat liver tumors: evidence for hepatic CYP2B induction and hepatocyte proliferation

1 reference

https://api.crossref.org/works/10.1177%2F0192623313482055

21 January 2018

Interstrain differences in susceptibility to liver carcinogenesis initiated by N-nitrosodiethylamine and its promotion by phenobarbital in C57BL/6NCr, C3H/HeNCrMTV- and DBA/2NCr mice

1 reference

https://api.crossref.org/works/10.1177%2F0192623313482055

21 January 2018

Inactivation of the hepatic cytochrome P450 system by conditional deletion of hepatic cytochrome P450 reductase.

1 reference

https://api.crossref.org/works/10.1177%2F0192623313482055

21 January 2018

Mode of action in relevance of rodent liver tumors to human cancer risk.

1 reference

https://api.crossref.org/works/10.1177%2F0192623313482055

21 January 2018

Nuclear receptors CAR and PXR cross talk with FOXO1 to regulate genes that encode drug-metabolizing and gluconeogenic enzymes

1 reference

https://api.crossref.org/works/10.1177%2F0192623313482055

21 January 2018

Cancer incidence among patients using antiepileptic drugs: a long-term follow-up of 28,000 patients

1 reference

https://api.crossref.org/works/10.1177%2F0192623313482055

21 January 2018

Evaluation of liver and thyroid toxicity in Sprague-Dawley rats after exposure to polybrominated diphenyl ether BDE-209

1 reference

https://api.crossref.org/works/10.1177%2F0192623313482055

21 January 2018

A framework for human relevance analysis of information on carcinogenic modes of action

1 reference

https://api.crossref.org/works/10.1177%2F0192623313482055

21 January 2018

Discrimination of tumorigenic triazole conazoles from phenobarbital by transcriptional analyses of mouse liver gene expression

1 reference

https://api.crossref.org/works/10.1177%2F0192623313482055

21 January 2018

Mode-of-action analysis for induction of rat liver tumors by pyrethrins: relevance to human cancer risk

1 reference

https://api.crossref.org/works/10.1177%2F0192623313482055

21 January 2018

Altered expression of GADD45 genes during the development of chemical-mediated liver hypertrophy and liver tumor promotion in rats

1 reference

https://api.crossref.org/works/10.1177%2F0192623313482055

21 January 2018

The flame retardants, polybrominated diphenyl ethers, are pregnane X receptor activators

1 reference

https://api.crossref.org/works/10.1177%2F0192623313482055

21 January 2018

Mouse liver effects of cyproconazole, a triazole fungicide: role of the constitutive androstane receptor.

1 reference

https://api.crossref.org/works/10.1177%2F0192623313482055

21 January 2018

Phenobarbital elicits unique, early changes in the expression of hepatic genes that affect critical pathways in tumor-prone B6C3F1 mice

1 reference

https://api.crossref.org/works/10.1177%2F0192623313482055

21 January 2018

The constitutive active/androstane receptor facilitates unique phenobarbital-induced expression changes of genes involved in key pathways in precancerous liver and liver tumors

1 reference

https://api.crossref.org/works/10.1177%2F0192623313482055

21 January 2018

Multiple genes exhibit phenobarbital-induced constitutive active/androstane receptor-mediated DNA methylation changes during liver tumorigenesis and in liver tumors

1 reference

https://api.crossref.org/works/10.1177%2F0192623313482055

21 January 2018

Orphan nuclear receptor constitutive active/androstane receptor-mediated alterations in DNA methylation during phenobarbital promotion of liver tumorigenesis.

1 reference

https://api.crossref.org/works/10.1177%2F0192623313482055

21 January 2018

Human constitutive androstane receptor (CAR) and pregnane X receptor (PXR) support the hypertrophic but not the hyperplastic response to the murine nongenotoxic hepatocarcinogens phenobarbital and chlordane in vivo.

1 reference

https://api.crossref.org/works/10.1177%2F0192623313482055

21 January 2018

IPCS conceptual framework for evaluating a mode of action for chemical carcinogenesis

1 reference

https://api.crossref.org/works/10.1177%2F0192623313482055

21 January 2018

The phenobarbital response enhancer module in the human bilirubin UDP-glucuronosyltransferase UGT1A1 gene and regulation by the nuclear receptor CAR.

1 reference

https://api.crossref.org/works/10.1177%2F0192623313482055

21 January 2018

Proliferative and nonproliferative lesions of the rat and mouse hepatobiliary system

1 reference

https://api.crossref.org/works/10.1177%2F0192623313482055

21 January 2018

Diverse roles of the nuclear orphan receptor CAR in regulating hepatic genes in response to phenobarbital

1 reference

https://api.crossref.org/works/10.1177%2F0192623313482055

21 January 2018

A 28-day oral dose toxicity study in Wistar rats enhanced to detect endocrine effects of decabromodiphenyl ether (decaBDE).

1 reference

https://api.crossref.org/works/10.1177%2F0192623313482055

21 January 2018

The nuclear receptor CAR mediates specific xenobiotic induction of drug metabolism

1 reference

https://api.crossref.org/works/10.1177%2F0192623313482055

21 January 2018

Phenobarbital mechanistic data and risk assessment: enzyme induction, enhanced cell proliferation, and tumor promotion

1 reference

https://api.crossref.org/works/10.1177%2F0192623313482055

21 January 2018

The orphan nuclear receptor constitutive active/androstane receptor is essential for liver tumor promotion by phenobarbital in mice

1 reference

https://api.crossref.org/works/10.1177%2F0192623313482055

21 January 2018

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