(Q42716874)

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Mangifera indica L. extract and mangiferin modulate cytochrome P450 and UDP-glucuronosyltransferase enzymes in primary cultures of human hepatocytes.

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scholarly article

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8 February 2020

Mangifera indica L. extract and mangiferin modulate cytochrome P450 and UDP-glucuronosyltransferase enzymes in primary cultures of human hepatocytes (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22815239%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Mangifera indica

object named as

Mangifera indica

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based on heuristic

inferred from title

6

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8 February 2020

José V Castell

7

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8 February 2020

author name string

Idania Rodeiro

1

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8 February 2020

M José Gómez-Lechón

2

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8 February 2020

Gabriela Perez

3

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8 February 2020

Ivones Hernandez

4

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8 February 2020

José Alfredo Herrera

5

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8 February 2020

M Teresa Donato

8

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8 February 2020

publication date

20 July 2012

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8 February 2020

Phytotherapy Research

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8 February 2020

27

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8 February 2020

5

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8 February 2020

745-752

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8 February 2020

The flavonoid galangin is an inhibitor of CYP1A1 activity and an agonist/antagonist of the aryl hydrocarbon receptor

1 reference

https://api.crossref.org/works/10.1002%2FPTR.4782

21 January 2018

Analgesic and antioxidant activity of mangiferin and its derivatives: the structure activity relationship

1 reference

https://api.crossref.org/works/10.1002%2FPTR.4782

21 January 2018

Validated assay for studying activity profiles of human liver UGTs after drug exposure: inhibition and induction studies

1 reference

https://api.crossref.org/works/10.1002%2FPTR.4782

21 January 2018

In vitro inhibition of multiple cytochrome P450 isoforms by xanthone derivatives from mangosteen extract.

1 reference

https://api.crossref.org/works/10.1002%2FPTR.4782

21 January 2018

In vivo acute toxicological studies of an antioxidant extract from Mangifera indica L. (Vimang).

1 reference

https://api.crossref.org/works/10.1002%2FPTR.4782

21 January 2018

Modulation of rat macrophage function by the Mangifera indica L. extracts Vimang and mangiferin.

1 reference

https://api.crossref.org/works/10.1002%2FPTR.4782

21 January 2018

Gallic acid indanone and mangiferin xanthone are strong determinants of immunosuppressive anti-tumour effects of Mangifera indica L. bark in MDA-MB231 breast cancer cells.

1 reference

https://api.crossref.org/works/10.1002%2FPTR.4782

21 January 2018

Antitumor, immunomodulatory and anti-HIV effect of mangiferin, a naturally occurring glucosylxanthone

1 reference

https://api.crossref.org/works/10.1002%2FPTR.4782

21 January 2018

Lack of in vivo embryotoxic and genotoxic activities of orally administered stem bark aqueous extract of Mangifera indica L. (Vimang).

1 reference

https://api.crossref.org/works/10.1002%2FPTR.4782

21 January 2018

Hepatocytes--the choice to investigate drug metabolism and toxicity in man: in vitro variability as a reflection of in vivo.

1 reference

https://api.crossref.org/works/10.1002%2FPTR.4782

21 January 2018

Inducibility of UDP-glucuronosyltransferase 1As by beta-naphthoflavone in HepG2 cells

1 reference

https://api.crossref.org/works/10.1002%2FPTR.4782

21 January 2018

Effects of (+)-catechin and (-)-epicatechin on heterocyclic amines-induced oxidative DNA damage

1 reference

https://api.crossref.org/works/10.1002%2FPTR.4782

21 January 2018

Flavonoids-potent and versatile biologically active compounds interacting with cytochromes P450.

1 reference

https://api.crossref.org/works/10.1002%2FPTR.4782

21 January 2018

New antidiabetic compounds, mangiferin and its glucoside

1 reference

https://api.crossref.org/works/10.1002%2FPTR.4782

21 January 2018

Strategies to in vitro assessment of major human CYP enzyme activities by using liquid chromatography tandem mass spectrometry

1 reference

https://api.crossref.org/works/10.1002%2FPTR.4782

21 January 2018

Assessment of cytochrome P450 induction in human hepatocytes using the cocktail strategy plus liquid chromatography tandem mass spectrometry.

1 reference

https://api.crossref.org/works/10.1002%2FPTR.4782

21 January 2018

Human hepatocyte culture systems for the in vitro evaluation of cytochrome P450 expression and regulation.

1 reference

https://api.crossref.org/works/10.1002%2FPTR.4782

21 January 2018

Isolation and quantitative analysis of phenolic antioxidants, free sugars, and polyols from mango (Mangifera indica L.) stem bark aqueous decoction used in Cuba as a nutritional supplement

1 reference

https://api.crossref.org/works/10.1002%2FPTR.4782

21 January 2018

The paradox of natural products as pharmaceuticals. Experimental evidences of a mango stem bark extract.

1 reference

https://api.crossref.org/works/10.1002%2FPTR.4782

21 January 2018

Comparison of major and trace element concentrations in 16 varieties of Cuban mango stem bark (Mangifera indica L.).

1 reference

https://api.crossref.org/works/10.1002%2FPTR.4782

21 January 2018

Antiinflammatory, analgesic and hypoglycemic effects of Mangifera indica Linn. (Anacardiaceae) stem-bark aqueous extract

1 reference

https://api.crossref.org/works/10.1002%2FPTR.4782

21 January 2018

Vimang (Mangifera indica L. extract) induces permeability transition in isolated mitochondria, closely reproducing the effect of mangiferin, Vimang's main component

1 reference

https://api.crossref.org/works/10.1002%2FPTR.4782

21 January 2018

Cytochrome P450 inhibitory potential of Triphala--a Rasayana from Ayurveda.

1 reference

https://api.crossref.org/works/10.1002%2FPTR.4782

21 January 2018

Anti-allergic properties of Mangifera indica L. extract (Vimang) and contribution of its glucosylxanthone mangiferin

1 reference

https://api.crossref.org/works/10.1002%2FPTR.4782

21 January 2018

Evaluation of the genotoxic potential of Mangifera indica L. extract (Vimang), a new natural product with antioxidant activity

1 reference

https://api.crossref.org/works/10.1002%2FPTR.4782

21 January 2018

Modulation of P450 enzymes by Cuban natural products rich in polyphenolic compounds in rat hepatocytes.

1 reference

https://api.crossref.org/works/10.1002%2FPTR.4782

21 January 2018

Inhibition of human P450 enzymes by natural extracts used in traditional medicine.

1 reference

https://api.crossref.org/works/10.1002%2FPTR.4782

21 January 2018

Phytochemical regulation of UDP-glucuronosyltransferases: implications for cancer prevention.

1 reference

https://api.crossref.org/works/10.1002%2FPTR.4782

21 January 2018

Optimization of the tetrazolium dye (MTT) colorimetric assay for cellular growth and viability

1 reference

https://api.crossref.org/works/10.1002%2FPTR.4782

21 January 2018

5,7-Dimethoxyflavone downregulates CYP1A1 expression and benzo[a]pyrene-induced DNA binding in Hep G2 cells

1 reference

https://api.crossref.org/works/10.1002%2FPTR.4782

21 January 2018

Induction of human UDP-glucuronosyltransferase UGT1A1 by flavonoids-structural requirements

1 reference

https://api.crossref.org/works/10.1002%2FPTR.4782

21 January 2018

Interactions of herbs with cytochrome P450.

1 reference

https://api.crossref.org/works/10.1002%2FPTR.4782

21 January 2018

A Microassay for Measuring Cytochrome P450IA1 and Cytochrome P450IIB1 Activities in Intact Human and Rat Hepatocytes Cultured on 96-Well Plates

1 reference

https://api.crossref.org/works/10.1002%2FPTR.4782

21 January 2018

Semi-automatic quantitative RT-PCR to measure CYP induction by drugs in human hepatocytes

1 reference

https://api.crossref.org/works/10.1002%2FPTR.4782

21 January 2018

Identifiers

10.1002/PTR.4782

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22815239%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22815239%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

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