(Q42726988)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21900507%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

title

Expression and functional properties of TRPM2 channels in dopaminergic neurons of the substantia nigra of the rat (English)

1 reference

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12 February 2020

1 reference

1 reference

3

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12 February 2020

Kenny Kwok Hin Chung

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21900507%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

2

Peter S Freestone

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21900507%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

language of work or name

English

0 references

publication date

7 September 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21900507%20AND%20SRC:MED&resulttype=core&format=json

Journal of Neurophysiology

12 February 2020

published in

1 reference

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12 February 2020

volume

106

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12 February 2020

issue

6

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12 February 2020

page(s)

2865-2875

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21900507%20AND%20SRC:MED&resulttype=core&format=json

Transient receptor potential A1 is a sensory receptor for multiple products of oxidative stress

12 February 2020

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Neuroprotection induced by vitamin E against oxidative stress in hippocampal neurons: involvement of TRPV1 channels

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Four Ca2+ ions activate TRPM2 channels by binding in deep crevices near the pore but intracellularly of the gate

21 January 2018

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Intracellular calcium activates TRPM2 and its alternative spliced isoforms

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TRPM2 channel opening in response to oxidative stress is dependent on activation of poly(ADP-ribose) polymerase

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TRPM2 is elevated in the tMCAO stroke model, transcriptionally regulated, and functionally expressed in C13 microglia.

21 January 2018

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Acute action of rotenone on nigral dopaminergic neurons--involvement of reactive oxygen species and disruption of Ca2+ homeostasis.

21 January 2018

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Cellular localization of TRPC3 channel in rat brain: preferential distribution to oligodendrocytes.

21 January 2018

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Protective role of hydrogen peroxide in oxygen-deprived dopaminergic neurones of the rat substantia nigra.

21 January 2018

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H(2)O(2)-mediated modulation of cytosolic signaling and organelle function in rat hippocampus.

21 January 2018

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Temperature sensitivity of dopaminergic neurons of the substantia nigra pars compacta: involvement of transient receptor potential channels

21 January 2018

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LTRPC2 Ca2+-permeable channel activated by changes in redox status confers susceptibility to cell death

21 January 2018

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N-(p-amylcinnamoyl)anthranilic acid (ACA): a phospholipase A(2) inhibitor and TRP channel blocker

21 January 2018

1 reference

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Flufenamic acid is a pH-dependent antagonist of TRPM2 channels

21 January 2018

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Inhibition of TRPM2 channels by the antifungal agents clotrimazole and econazole.

21 January 2018

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Characterisation of recombinant rat TRPM2 and a TRPM2-like conductance in cultured rat striatal neurones

21 January 2018

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Tuning the excitability of midbrain dopamine neurons by modulating the Ca2+ sensitivity of SK channels.

21 January 2018

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TRPM2 channel properties, functions and therapeutic potentials

21 January 2018

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A critical role of TRPM2 in neuronal cell death by hydrogen peroxide

21 January 2018

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Biphasic effect of hydrogen peroxide on field potentials in rat hippocampal slices.

21 January 2018

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TRPM2: a calcium influx pathway regulated by oxidative stress and the novel second messenger ADP-ribose

21 January 2018

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TRPM2 functions as a lysosomal Ca2+-release channel in beta cells

21 January 2018

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Regulation of Substantia Nigra Pars Reticulata GABAergic Neuron Activity by H₂O₂ via Flufenamic Acid-Sensitive Channels and K(ATP) Channels

21 January 2018

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N-arachidonoyl-dopamine tunes synaptic transmission onto dopaminergic neurons by activating both cannabinoid and vanilloid receptors

21 January 2018

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Critical intracellular Ca2+ dependence of transient receptor potential melastatin 2 (TRPM2) cation channel activation

21 January 2018

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Reactive oxygen species inhibit polycystin-2 (TRPP2) cation channel activity in term human syncytiotrophoblast

21 January 2018

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Molecular cloning of a novel putative Ca2+ channel protein (TRPC7) highly expressed in brain

21 January 2018

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A calcium influx pathway regulated separately by oxidative stress and ADP-Ribose in TRPM2 channels: single channel events

21 January 2018

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Antagonist effect of flufenamic acid on TRPM2 cation channels activated by hydrogen peroxide.

21 January 2018

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Neuroprotective effect of hydrogen peroxide on an in vitro model of brain ischaemia.

21 January 2018

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Ca2+-dependent induction of TRPM2 currents in hippocampal neurons

21 January 2018

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Chemotaxis of mouse bone marrow neutrophils and dendritic cells is controlled by adp-ribose, the major product generated by the CD38 enzyme reaction.

21 January 2018

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ADP-ribose gating of the calcium-permeable LTRPC2 channel revealed by Nudix motif homology

21 January 2018

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Accumulation of free ADP-ribose from mitochondria mediates oxidative stress-induced gating of TRPM2 cation channels

21 January 2018

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TRPC3 and TRPC4 associate to form a redox-sensitive cation channel. Evidence for expression of native TRPC3-TRPC4 heteromeric channels in endothelial cells.

21 January 2018

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An introduction to TRP channels

21 January 2018

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Oxidative stress and the pathogenesis of neurodegenerative disorders

21 January 2018

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Immunocyte Ca2+ influx system mediated by LTRPC2.

21 January 2018

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Hydrogen-peroxide-induced toxicity of rat striatal neurones involves activation of a non-selective cation channel.

21 January 2018

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Regulation of TRPM2 by extra- and intracellular calcium.

21 January 2018

1 reference

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Multiple hit hypotheses for dopamine neuron loss in Parkinson's disease

21 January 2018

1 reference

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TRPM2: a multifunctional ion channel for calcium signalling.

21 January 2018

1 reference

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TRPM2 activation by cyclic ADP-ribose at body temperature is involved in insulin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FJN.00994.2010

Identification of direct and indirect effectors of the transient receptor potential melastatin 2 (TRPM2) cation channel.

21 January 2018

1 reference

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Involvement of transient receptor potential-like channels in responses to mGluR-I activation in midbrain dopamine neurons.

21 January 2018

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Glutamate transporters are oxidant-vulnerable: a molecular link between oxidative and excitotoxic neurodegeneration?

21 January 2018

1 reference

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Characterization of human and mouse TRPM2 genes: identification of a novel N-terminal truncated protein specifically expressed in human striatum.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FJN.00994.2010

Hydrogen peroxide sensing and signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FJN.00994.2010

Activation of the cation channel long transient receptor potential channel 2 (LTRPC2) by hydrogen peroxide. A splice variant reveals a mode of activation independent of ADP-ribose.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FJN.00994.2010

H2O 2-stimulated Ca2+ influx via TRPM2 is not the sole determinant of subsequent cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FJN.00994.2010

Identification of pore residues engaged in determining divalent cationic permeation in transient receptor potential melastatin subtype channel 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FJN.00994.2010

A novel TRPM2 isoform inhibits calcium influx and susceptibility to cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FJN.00994.2010

TRPM2 is an ion channel that modulates hematopoietic cell death through activation of caspases and PARP cleavage.

21 January 2018

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https://api.crossref.org/works/10.1152%2FJN.00994.2010

Oxidative stress in Parkinson's disease: a mechanism of pathogenic and therapeutic significance

21 January 2018

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21 January 2018

Identifiers

DOI

10.1152/JN.00994.2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21900507%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

1 reference