(Q46507468)

English

Partial mitochondrial inhibition causes striatal dopamine release suppression and medium spiny neuron depolarization via H2O2 elevation, not ATP depletion.

scientific article published in October 2005

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scholarly article

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8 January 2020

Partial mitochondrial inhibition causes striatal dopamine release suppression and medium spiny neuron depolarization via H2O2 elevation, not ATP depletion (English)

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16251452%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

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Margaret E Rice

3

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8 January 2020

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Li Bao

1

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8 January 2020

Marat V Avshalumov

2

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8 January 2020

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1 October 2005

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8 January 2020

Journal of Neuroscience

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8 January 2020

25

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8 January 2020

43

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8 January 2020

10029-10040

1 reference

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8 January 2020

Alternative sulfonylurea receptor expression defines metabolic sensitivity of K-ATP channels in dopaminergic midbrain neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Etiology and pathogenesis of Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibitory control of neostriatal projection neurons by GABAergic interneurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251452

12 December 2020

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Dopamine oxidation alters mitochondrial respiration and induces permeability transition in brain mitochondria: implications for Parkinson's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Optical imaging reveals elevated intracellular chloride in hippocampal pyramidal neurons after oxidative stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The sulphonylurea glibenclamide inhibits voltage dependent potassium currents in human atrial and ventricular myocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative stress and genetics in the pathogenesis of Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular factors controlling neuronal vulnerability in the brain: a lesson from the striatum

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronic systemic pesticide exposure reproduces features of Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ionic mechanisms underlying differential vulnerability to ischemia in striatal neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251452

12 December 2020

based on heuristic

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H(2)O(2) is a novel, endogenous modulator of synaptic dopamine release

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DeltaPsi(m)-Dependent and -independent production of reactive oxygen species by rat brain mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Complex I and Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial involvement in Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative relationship between inhibition of respiratory complexes and formation of reactive oxygen species in isolated nerve terminals.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Subcutaneous rotenone exposure causes highly selective dopaminergic degeneration and alpha-synuclein aggregation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronic systemic complex I inhibition induces a hypokinetic multisystem degeneration in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hydrogen-peroxide-induced toxicity of rat striatal neurones involves activation of a non-selective cation channel.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutamate-dependent inhibition of dopamine release in striatum is mediated by a new diffusible messenger, H2O2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid reduction of ATP synthesis and lack of free radical formation by MPP+ in rat brain synaptosomes and mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Variable dopamine release probability and short-term plasticity between functional domains of the primate striatum.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TRPM2 Ca2+ permeable cation channels: from gene to biological function

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial mechanisms of neural cell death and neuroprotective interventions in Parkinson's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The rotenone model of Parkinson's disease: genes, environment and mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251452

12 December 2020

based on heuristic

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The environment and Parkinson's disease: is the nigrostriatal system preferentially targeted by neurotoxins?

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Parkinson's disease: mechanisms and models

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251452

12 December 2020

based on heuristic

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Activation of ATP-sensitive K+ (K(ATP)) channels by H2O2 underlies glutamate-dependent inhibition of striatal dopamine release

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular Pathways of Neurodegeneration in Parkinson's Disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of superoxide-producing sites in isolated brain mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of toxicity in rotenone models of Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early ionic and membrane potential changes caused by the pesticide rotenone in striatal cholinergic interneurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transient receptor potential-like channels mediate metabotropic glutamate receptor EPSCs in rat dopamine neurones

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuronal vulnerability following inhibition of mitochondrial complex II: a possible ionic mechanism for Huntington's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Initiation of neuronal damage by complex I deficiency and oxidative stress in Parkinson's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hereditary early-onset Parkinson's disease caused by mutations in PINK1

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Behavioral and immunohistochemical effects of chronic intravenous and subcutaneous infusions of varying doses of rotenone

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotine amplifies reward-related dopamine signals in striatum

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TRP ion channels in the nervous system.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Shift in the localization of sites of hydrogen peroxide production in brain mitochondria by mitochondrial stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

L-DOPA reverses the hypokinetic behaviour and rigidity in rotenone-treated rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Flufenamic acid is a pH-dependent antagonist of TRPM2 channels

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rotenone induces oxidative stress and dopaminergic neuron damage in organotypic substantia nigra cultures.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endogenous hydrogen peroxide regulates the excitability of midbrain dopamine neurons via ATP-sensitive potassium channels.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NMDA enhances a depolarization-activated inward current in subthalamic neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of TRPM channels in cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial inhibition and oxidative stress: reciprocating players in neurodegeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The neural network of the basal ganglia as revealed by the study of synaptic connections of identified neurones

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Compensations after lesions of central dopaminergic neurons: some clinical and basic implications

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diffusion characteristics and extracellular volume fraction during normoxia and hypoxia in slices of rat neostriatum.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial complex I deficiency in Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abnormalities of the electron transport chain in idiopathic Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The structure of the caudate nucleus of the cat: light and electron microscopy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intracellular ATP directly blocks K+ channels in pancreatic B-cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ATP-regulated K+ channels in cardiac muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Generation of H2O in biomembranes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutamate induces the production of reactive oxygen species in cultured forebrain neurons following NMDA receptor activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potassium currents responsible for inward and outward rectification in rat neostriatal spiny projection neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of an ATP-sensitive K+ channel in spiny neurons of rat caudate nucleus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sulphonylureas reduce the slowly inactivating D-type outward current in rat hippocampal neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Extracellular dopamine concentration in the retina of the clawed frog, Xenopus laevis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Threshold effects and control of oxidative phosphorylation in nonsynaptic rat brain mitochondria.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Direct activation of the ATP-sensitive potassium channel by oxygen free radicals in guinea-pig ventricular cells: its potentiation by MgADP.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Opposite membrane potential changes induced by glucose deprivation in striatal spiny neurons and in large aspiny interneurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Systemic administration of rotenone produces selective damage in the striatum and globus pallidus, but not in the substantia nigra.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vesicular monoamine transporter-2: immunogold localization in striatal axons and terminals.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

KATP-channel on the somata of spiny neurones in rat caudate nucleus: regulation by drugs and nucleotides

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of striatal energy metabolism produces cell loss in the ipsilateral substantia nigra.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential compartmentalization of brain ascorbate and glutathione between neurons and glia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Substrate and site specificity of hydrogen peroxide generation in mouse mitochondria.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlating structure and function in ATP-sensitive K+ channels.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interference of H2O2 with stimulus-secretion coupling in mouse pancreatic beta-cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sodium influx plays a major role in the membrane depolarization induced by oxygen and glucose deprivation in rat striatal spiny neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16251452

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.2652-05.2005

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16251452%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16251452%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16251452%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

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