(Q42829584)

8 November 2017

Peptides from purified soybean beta-conglycinin inhibit fatty acid synthase by interaction with the thioesterase catalytic domain (English)

1 reference

Cristina Martínez Villaluenga

8 November 2017

0 references

series ordinal

1

1 reference

8 November 2017

4

Elvira Gonzalez de Mejia

1 reference

8 November 2017

Sanjeewa G Rupasinghe

series ordinal

2

1 reference

PubMed ID

20148945

8 November 2017

Mary A Schuler

series ordinal

3

1 reference

PubMed ID

20148945

8 November 2017

language of work or name

English

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publication date

8 February 2010

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8 November 2017

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8 November 2017

277

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8 November 2017

6

1 reference

8 November 2017

1481-1493

1 reference

Human fatty acid synthase: structure and substrate selectivity of the thioesterase domain

8 November 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07577.X

The type I fatty acid and polyketide synthases: a tale of two megasynthases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07577.X

Fatty acid synthase gene expression in human adipose tissue: association with obesity and type 2 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07577.X

Metabolic targeting of cancers: from molecular mechanisms to therapeutic strategies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07577.X

Does FASing out new fat in the hypothalamus make you slim?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07577.X

Brain fatty acid synthase activates PPARalpha to maintain energy homeostasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07577.X

Fatty acid metabolism as a target for obesity treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07577.X

Reduced food intake and body weight in mice treated with fatty acid synthase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07577.X

Inactivation of hypothalamic FAS protects mice from diet-induced obesity and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07577.X

Inhibition of fatty acid synthase by Orlistat accelerates gastric tumor cell apoptosis in culture and increases survival rates in gastric tumor bearing mice in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07577.X

Fatty acid synthase inhibitors cerulenin and C75 retard growth and induce caspase-dependent apoptosis in human melanoma A-375 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07577.X

C75 [4-methylene-2-octyl-5-oxo-tetrahydro-furan-3-carboxylic acid] activates carnitine palmitoyltransferase-1 in isolated mitochondria and intact cells without displacement of bound malonyl CoA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07577.X

Characterization of the inactivation of rat fatty acid synthase by C75: inhibition of partial reactions and protection by substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07577.X

Crystal structure of the thioesterase domain of human fatty acid synthase inhibited by Orlistat

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07577.X

Discovery of GSK837149A, an inhibitor of human fatty acid synthase targeting the beta-ketoacyl reductase reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07577.X

Induction of cancer cell apoptosis by flavonoids is associated with their ability to inhibit fatty acid synthase activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07577.X

Inhibition of fatty acid synthase by polyphenols

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07577.X

Fatty acid synthase inhibitors from Geum japonicum Thunb. var. chinense

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07577.X

Beta-conglycinin embeds active peptides that inhibit lipid accumulation in 3T3-L1 adipocytes in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07577.X

The crystal structure of a mammalian fatty acid synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07577.X

Orlistat is a novel inhibitor of fatty acid synthase with antitumor activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07577.X

Fatty acid synthase: association with insulin resistance, type 2 diabetes, and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07577.X

The galloyl moiety of green tea catechins is the critical structural feature to inhibit fatty-acid synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07577.X

Inhibitory effects of flavonoids on animal fatty acid synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07577.X

Role of dietary soy protein in obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07577.X

Intracerebroventricular administration of soy protein hydrolysates reduces body weight without affecting food intake in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07577.X

Dietary soy protein inhibits DNA damage and cell survival of colon epithelial cells through attenuated expression of fatty acid synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07577.X

Inhibition of fatty acid synthase prevents preadipocyte differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07577.X

Positive feedback regulation between AKT activation and fatty acid synthase expression in ovarian carcinoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07577.X

Structure-function relationships in peptoids: recent advances toward deciphering the structural requirements for biological function

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07577.X

beta-Conglycinins among sources of bioactives in hydrolysates of different soybean varieties that inhibit leukemia cells in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07577.X

Novel antagonists of the thioesterase domain of human fatty acid synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07577.X

Mechanism and substrate recognition of human holo ACP synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07577.X

All-atom empirical potential for molecular modeling and dynamics studies of proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07577.X

2D depiction of protein-ligand complexes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07577.X

10.1111/J.1742-4658.2010.07577.X

21 January 2018

Identifiers

DOI

1 reference

8 November 2017

1 reference

PubMed ID

20148945