(Q42858751)

8 November 2017

Synthesis and evaluation of pyrazolone compounds as SARS-coronavirus 3C-like protease inhibitors (English)

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8 November 2017

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R Ramajayam

1

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8 November 2017

Kian-Pin Tan

series ordinal

2

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8 November 2017

Hun-Ge Liu

series ordinal

3

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8 November 2017

Po-Huang Liang

series ordinal

4

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8 November 2017

language of work or name

English

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publication date

25 September 2010

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Bioorganic & Medicinal Chemistry

8 November 2017

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8 November 2017

18

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8 November 2017

22

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8 November 2017

7849-7854

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A novel coronavirus associated with severe acute respiratory syndrome

8 November 2017

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12 December 2020

Development of Broad-Spectrum Halomethyl Ketone Inhibitors Against Coronavirus Main Protease 3CLpro

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12 December 2020

Structure-based design and synthesis of highly potent SARS-CoV 3CL protease inhibitors

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12 December 2020

Stable Benzotriazole Esters as Mechanism-Based Inactivators of the Severe Acute Respiratory Syndrome 3CL Protease

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12 December 2020

A new lead for nonpeptidic active-site-directed inhibitors of the severe acute respiratory syndrome coronavirus main protease discovered by a combination of screening and docking methods

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12 December 2020

Structural Basis of Inhibition Specificities of 3C and 3C-like Proteases by Zinc-coordinating and Peptidomimetic Compounds

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12 December 2020

Identification of novel inhibitors of the SARS coronavirus main protease 3CLpro.

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12 December 2020

Polyprotein cleavage mechanism of SARS CoV Mpro and chemical modification of the octapeptide

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12 December 2020

Coronavirus main proteinase (3CLpro) structure: basis for design of anti-SARS drugs

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12 December 2020

New developments for the design, synthesis and biological evaluation of potent SARS-CoV 3CL(pro) inhibitors

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12 December 2020

Evaluation of metal-conjugated compounds as inhibitors of 3CL protease of SARS-CoV.

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12 December 2020

Protective effects of MCI-186 on cerebral ischemia: possible involvement of free radical scavenging and antioxidant actions.

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12 December 2020

Identification of novel small-molecule inhibitors of severe acute respiratory syndrome-associated coronavirus by chemical genetics.

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12 December 2020

Design and synthesis of cinanserin analogs as severe acute respiratory syndrome coronavirus 3CL protease inhibitors

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12 December 2020

High-throughput screening identifies inhibitors of the SARS coronavirus main proteinase

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12 December 2020

Synthesis and evaluation of isatin derivatives as effective SARS coronavirus 3CL protease inhibitors

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12 December 2020

Small molecules targeting severe acute respiratory syndrome human coronavirus

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12 December 2020

Individual and common inhibitors of coronavirus and picornavirus main proteases

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12 December 2020

Myocardial protection of MCI-186 in rabbit ischemia-reperfusion.

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12 December 2020

Discovery of potent anilide inhibitors against the severe acute respiratory syndrome 3CL protease

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12 December 2020

Virtual screening of novel noncovalent inhibitors for SARS-CoV 3C-like proteinase.

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12 December 2020

Development of potent inhibitors of the coxsackievirus 3C protease

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12 December 2020

The crystal structures of severe acute respiratory syndrome virus main protease and its complex with an inhibitor

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12 December 2020

Design, synthesis, and evaluation of 3C protease inhibitors as anti-enterovirus 71 agents.

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12 December 2020

Design and synthesis of peptidomimetic severe acute respiratory syndrome chymotrypsin-like protease inhibitors

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12 December 2020

Inhibition of the severe acute respiratory syndrome 3CL protease by peptidomimetic alpha,beta-unsaturated esters

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12 December 2020

A pyrimidine-pyrazolone nucleoside chimera with potent in vitro anti-orthopoxvirus activity

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12 December 2020

Effects of a novel free radical scavenger, MCl-186, on ischemic brain damage in the rat distal middle cerebral artery occlusion model.

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12 December 2020

Characterization of a novel coronavirus associated with severe acute respiratory syndrome

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12 December 2020

Structure-based design, synthesis, and biological evaluation of peptidomimetic SARS-CoV 3CLpro inhibitors

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12 December 2020

Synthesis and evaluation of keto-glutamine analogues as potent inhibitors of severe acute respiratory syndrome 3CLpro

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12 December 2020

Discovering severe acute respiratory syndrome coronavirus 3CL protease inhibitors: virtual screening, surface plasmon resonance, and fluorescence resonance energy transfer assays

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12 December 2020

Characterization of SARS main protease and inhibitor assay using a fluorogenic substrate

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12 December 2020

Cinanserin is an inhibitor of the 3C-like proteinase of severe acute respiratory syndrome coronavirus and strongly reduces virus replication in vitro

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12 December 2020

Synthesis, docking studies, and evaluation of pyrimidines as inhibitors of SARS-CoV 3CL protease

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12 December 2020

Conservation of amino acids in human rhinovirus 3C protease correlates with broad-spectrum antiviral activity of rupintrivir, a novel human rhinovirus 3C protease inhibitor.

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12 December 2020

Coronavirus as a possible cause of severe acute respiratory syndrome

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12 December 2020

10.1016/J.BMC.2010.09.050

Identifiers

DOI

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8 November 2017

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