(Q42871498)

9 November 2017

Next generation maleimides enable the controlled assembly of antibody-drug conjugates via native disulfide bond bridging (English)

1 reference

9 November 2017

1 reference

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25103319%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Vijay Chudasama

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25103319%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

James R. Baker

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25103319%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

author name string

Felix F Schumacher

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25103319%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

João P M Nunes

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25103319%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Antoine Maruani

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25103319%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Mark E B Smith

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25103319%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Kerry A Chester

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25103319%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

publication date

1 October 2014

1 reference

Organic and Biomolecular Chemistry

9 November 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25103319%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

volume

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25103319%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

page(s)

7261-7269

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25103319%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

issue

37

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25103319%20AND%20SRC:MED&resulttype=core&format=json

Site-specific antibody drug conjugates for cancer therapy

1 June 2020

cites work

1 reference

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A mild synthesis of N-functionalised bromomaleimides, thiomaleimides and bromopyridazinediones

27 May 2018

1 reference

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Acid-cleavable thiomaleamic acid linker for homogeneous antibody-drug conjugation.

27 May 2018

1 reference

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Homogeneous antibody fragment conjugation by disulfide bridging introduces 'spinostics'.

27 May 2018

1 reference

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Antibody-drug conjugates for the treatment of cancer

27 May 2018

1 reference

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Trastuzumab emtansine for HER2-positive advanced breast cancer

27 May 2018

1 reference

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Synthesis of site-specific antibody-drug conjugates using unnatural amino acids

27 May 2018

1 reference

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Conjugation site modulates the in vivo stability and therapeutic activity of antibody-drug conjugates.

27 May 2018

1 reference

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Brentuximab Vedotin (SGN-35).

27 May 2018

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Tunable reagents for multi-functional bioconjugation: reversible or permanent chemical modification of proteins and peptides by control of maleimide hydrolysis

27 May 2018

1 reference

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The development of pyrrolobenzodiazepines as antitumour agents

27 May 2018

1 reference

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Analytical methods for physicochemical characterization of antibody drug conjugates

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4159697

In situ maleimide bridging of disulfides and a new approach to protein PEGylation

27 May 2018

1 reference

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Brentuximab vedotin (SGN-35) for relapsed CD30-positive lymphomas

27 May 2018

1 reference

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Chemoenzymatic methods for site-specific protein modification

27 May 2018

1 reference

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Engineered thio-trastuzumab-DM1 conjugate with an improved therapeutic index to target human epidermal growth factor receptor 2-positive breast cancer

27 May 2018

1 reference

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Antibody-drug conjugates: targeted drug delivery for cancer

27 May 2018

1 reference

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Site-specific conjugation of a cytotoxic drug to an antibody improves the therapeutic index.

27 May 2018

1 reference

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Trastuzumab--mechanism of action and use in clinical practice

27 May 2018

1 reference

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Enhanced activity of monomethylauristatin F through monoclonal antibody delivery: effects of linker technology on efficacy and toxicity

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4159697

EphB2 as a therapeutic antibody drug target for the treatment of colorectal cancer

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4159697

Limitations of radiolabeled monoclonal antibodies for localization of human neoplasms

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4159697

Doxorubicin conjugates of monoclonal antibodies to hepatoma-associated antigens

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4159697

Auristatin antibody drug conjugate physical instability and the role of drug payload

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4159697

Antibody-drug conjugates: present and future.

16 August 2018

1 reference

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Reagents for astatination of biomolecules. 6. An intact antibody conjugated with a maleimido-closo-decaborate(2-) reagent via sulfhydryl groups had considerably higher kidney concentrations than the same antibody conjugated with an isothiocyanato-cl

16 August 2018

1 reference

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Impact of drug conjugation on pharmacokinetics and tissue distribution of anti-STEAP1 antibody-drug conjugates in rats

16 August 2018

1 reference

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Physicochemical stability of the antibody-drug conjugate Trastuzumab-DM1: changes due to modification and conjugation processes

16 August 2018

1 reference

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Paul Ehrlich's magic bullet concept: 100 years of progress.

16 August 2018

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A Comparative Study of Bioorthogonal Reactions with Azides

16 August 2018

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16 August 2018

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Engineered antibody-drug conjugates with defined sites and stoichiometries of drug attachment.

21 January 2018

1 reference

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Cathepsin B-labile dipeptide linkers for lysosomal release of doxorubicin from internalizing immunoconjugates: model studies of enzymatic drug release and antigen-specific in vitro anticancer activity

16 August 2018

1 reference

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Novel peptide linkers for highly potent antibody-auristatin conjugate

16 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1039%2FC4OB01550A

Development of potent monoclonal antibody auristatin conjugates for cancer therapy

21 January 2018

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12 December 2020

Synthesis and evaluation of hydrophilic linkers for antibody-maytansinoid conjugates

1 reference

12 December 2020

E-selectin up-regulation allows for targeted drug delivery in prostate cancer

1 reference

12 December 2020

Effects of drug loading on the antitumor activity of a monoclonal antibody drug conjugate

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12 December 2020

In vivo drug-linker stability of an anti-CD30 dipeptide-linked auristatin immunoconjugate

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12 December 2020

Synthesis of substituted bis(heteroaryl)maleimides

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18 October 2022

https://opencitations.net/index/coci/api/v1/citations/10.1016/J.TET.2005.03.016

Identifiers

DOI

10.1039/C4OB01550A

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25103319%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25103319%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25103319%20AND%20SRC:MED&resulttype=core&format=json