(Q42905649)

English

5-HT2B receptors are expressed on astrocytes from brain and in culture and are a chronic target for all five conventional 'serotonin-specific reuptake inhibitors'.

scientific article published on May 2010

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

10 November 2017

5-HT2B receptors are expressed on astrocytes from brain and in culture and are a chronic target for all five conventional 'serotonin-specific reuptake inhibitors'. (English)

1 reference

Europe PubMed Central

PubMed publication ID

10 November 2017

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Maiken Nedergaard

7

object named as

Maiken Nedergaard

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Steven A. Goldman

6

object named as

Steven A Goldman

0 references

8

object named as

Leif Hertz

1 reference

Europe PubMed Central

PubMed publication ID

10 November 2017

author name string

Shiquen Zhang

1

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Europe PubMed Central

PubMed publication ID

10 November 2017

Baoman Li

2

1 reference

Europe PubMed Central

PubMed publication ID

10 November 2017

Ditte Lovatt

3

1 reference

Europe PubMed Central

PubMed publication ID

10 November 2017

Junnan Xu

4

1 reference

Europe PubMed Central

PubMed publication ID

10 November 2017

Dan Song

5

1 reference

Europe PubMed Central

PubMed publication ID

10 November 2017

Steven A Goldman

6

1 reference

Europe PubMed Central

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10 November 2017

Liang Peng

9

1 reference

Europe PubMed Central

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10 November 2017

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publication date

1 May 2010

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Europe PubMed Central

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10 November 2017

Neuron Glia Biology

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Europe PubMed Central

PubMed publication ID

10 November 2017

6

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Europe PubMed Central

PubMed publication ID

10 November 2017

2

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Europe PubMed Central

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10 November 2017

113-125

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Europe PubMed Central

PubMed publication ID

10 November 2017

Dysfunctional attitudes and 5-HT2 receptors during depression and self-harm.

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Serotonin transporter occupancy of five selective serotonin reuptake inhibitors at different doses: an [11C]DASB positron emission tomography study.

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Detection of 5-hydroxytryptamine2 receptors by radioligand binding, northern blot analysis, and Ca2+ responses in rat primary astrocyte cultures.

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Fluoxetine treatment of depression. Clinical effects, drug concentrations and monoamine metabolites and N-terminally extended substance P in cerebrospinal fluid.

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

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Glia as a putative target for antidepressant treatments

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The pharmacology and distribution of human 5‐hydroxytryptamine2B (5‐HT2b) receptor gene products: comparison with 5‐HT2a and 5‐HT2c receptors

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Unbound drug concentration in brain homogenate and cerebral spinal fluid at steady state as a surrogate for unbound concentration in brain interstitial fluid

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Blockade by newly-developed antidepressants of biogenic amine uptake into rat brain synaptosomes.

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Fluoxetine-mediated 5-HT2B receptor stimulation in astrocytes causes EGF receptor transactivation and ERK phosphorylation

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Arachidonic acid stimulates glucose uptake in cerebral cortical astrocytes

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Comparison of two-phase treatment with imipramine or fluvoxamine, both followed by lithium addition, in inpatients with major depressive disorder.

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Chronic treatment of astrocytes with therapeutically relevant fluoxetine concentrations enhances cPLA2 expression secondary to 5-HT2B-induced, transactivation-mediated ERK1/2 phosphorylation

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21 January 2018

In vitro and in vivo characterisation of [11C]-DASB: a probe for in vivo measurements of the serotonin transporter by positron emission tomography.

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21 January 2018

Pharmacological and Genetic Characterization of Two Selective Serotonin Transporter Ligands: 2-[2-(Dimethylaminomethylphenylthio)]-5-fluoromethylphenylamine (AFM) and 3-Amino-4-[2-(dimethylaminomethyl-phenylthio)]benzonitrile (DASB)

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Up-regulation of 5-HT2B receptor density and receptor-mediated glycogenolysis in mouse astrocytes by long-term fluoxetine administration

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21 January 2018

Occupancy of brain serotonin transporters during treatment with paroxetine in patients with social phobia: a positron emission tomography study with 11C McN 5652.

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Pooled analysis of antidepressant levels in lactating mothers, breast milk, and nursing infants

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Plasma and tissue protein binding of drugs in pharmacokinetics

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Serotonin transporter occupancy of high-dose selective serotonin reuptake inhibitors during major depressive disorder measured with [11C]DASB positron emission tomography.

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Prostaglandin E(2)-synthesizing enzymes in fever: differential transcriptional regulation

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Clinical pharmacokinetics of selective serotonin reuptake inhibitors

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Pharmacological profile of antidepressants and related compounds at human monoamine transporters

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Plasma polyunsaturated fatty acids and regional cerebral glucose metabolism in major depression

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Relationship between brain serotonin transporter binding, plasma concentration and behavioural effect of selective serotonin reuptake inhibitors

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21 January 2018

Changes in antidepressant metabolism and dosing across pregnancy and early postpartum

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Functional studies in cultured astrocytes

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Establishment of a novel enzyme-linked immunosorbent assay for Thy-1; quantitative assessment of neuronal degeneration

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The effect of paroxetine on 5-HT(2A) receptors in depression: an [(18)F]setoperone PET imaging study

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Effects of dosage and CYP2D6-mutated allele on plasma concentration of paroxetine

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21 January 2018

5-Hydroxytryptamine2B receptors stimulate Ca2+ increases in cultured astrocytes from three different brain regions

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21 January 2018

Potassium-stimulated calcium uptake in astrocytes and its potent inhibition by nimodipine

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Bioenergetics of cerebral ischemia: a cellular perspective

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Evidence for possible involvement of 5-HT(2B) receptors in the cardiac valvulopathy associated with fenfluramine and other serotonergic medications

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Kinetic characteristics of the glutamate uptake into normal astrocytes in cultures

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Serotonergic drugs and valvular heart disease

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A comparison of brain and serum pharmacokinetics of R-fluoxetine and racemic fluoxetine: A 19-F MRS study

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Therapeutic targets in pulmonary arterial hypertension

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5-Hydroxytryptamine stimulates the formation of inositol phosphate in astrocytes from different regions of the brain

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Pharmacokinetics of sertraline across pregnancy and postpartum

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Chronic fluoxetine upregulates activity, protein and mRNA levels of cytosolic phospholipase A2 in rat frontal cortex

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Imaging neuronal subsets in transgenic mice expressing multiple spectral variants of GFP

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Modifications in phospholipase D activity and isoform expression occur upon maturation and differentiation in vivo and in vitro in human myeloid cells

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Adrenergic and 5-HT2 receptors on the same astroglial cell. A microspectrofluorimetric study on cytosolic Ca2+ responses in single cells in primary culture

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Clinical pharmacokinetics of sertraline

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Pharmacological characterization of selective serotonin reuptake inhibitors (SSRIs).

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Delivery outcome after maternal use of antidepressant drugs in pregnancy: an update using Swedish data

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The transcriptome and metabolic gene signature of protoplasmic astrocytes in the adult murine cortex

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7 January 2021

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Further evidence that fluoxetine interacts with a 5-HT2C receptor in glial cells

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7 January 2021

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Activation of glycogen phosphorylase by serotonin and 3,4-methylenedioxymethamphetamine in astroglial-rich primary cultures: involvement of the 5-HT2A receptor

1 reference

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Astrocytic transactivation by alpha2A-adrenergic and 5-HT2B serotonergic signaling

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Brain pharmacokinetics and tissue distribution in vivo of fluvoxamine and fluoxetine by fluorine magnetic resonance spectroscopy

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Relationship between clinical effects, serum drug concentration and serotonin uptake inhibition in depressed patients treated with citalopram. A double-blind comparison of three dose levels

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Adrenoceptors in brain: cellular gene expression and effects on astrocytic metabolism and [Ca(2+)]i

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Biochemical effects and drug levels in rats after long-term treatment with the specific 5-HT-uptake inhibitor, citalopram

1 reference

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7 January 2021

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Identifiers

10.1017/S1740925X10000141

1 reference

Europe PubMed Central

PubMed publication ID

10 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

10 November 2017

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