(Q42931493)

English

Inhibition of oral midazolam clearance by boosting doses of ritonavir, and by 4,4-dimethyl-benziso-(2H)-selenazine (ALT-2074), an experimental catalytic mimic of glutathione oxidase

scientific article published on December 2009

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

11 November 2017

Inhibition of oral midazolam clearance by boosting doses of ritonavir, and by 4,4-dimethyl-benziso-(2H)-selenazine (ALT-2074), an experimental catalytic mimic of glutathione oxidase (English)

1 reference

Europe PubMed Central

PMC publication ID

11 November 2017

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

Jerold S. Harmatz

4

object named as

Jerold S Harmatz

1 reference

Europe PubMed Central

PMC publication ID

11 November 2017

David J. Greenblatt

1

object named as

David J Greenblatt

1 reference

Europe PubMed Central

PMC publication ID

11 November 2017

Michael H Court

8

object named as

Michael H Court

1 reference

Europe PubMed Central

PMC publication ID

11 November 2017

7

object named as

Miguel A Zinny

1 reference

Europe PubMed Central

PMC publication ID

11 November 2017

Lauren E Oleson

3

object named as

Lauren E Oleson

1 reference

Europe PubMed Central

PMC publication ID

11 November 2017

author name string

Diane E Peters

2

1 reference

Europe PubMed Central

PMC publication ID

11 November 2017

Malcolm W MacNab

5

1 reference

Europe PubMed Central

PMC publication ID

11 November 2017

Noah Berkowitz

6

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Europe PubMed Central

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11 November 2017

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publication date

1 December 2009

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Europe PubMed Central

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11 November 2017

British Journal of Clinical Pharmacology

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Europe PubMed Central

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11 November 2017

68

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Europe PubMed Central

PMC publication ID

11 November 2017

6

1 reference

Europe PubMed Central

PMC publication ID

11 November 2017

920-927

1 reference

Europe PubMed Central

PMC publication ID

11 November 2017

Mechanism of ritonavir changes in methadone pharmacokinetics and pharmacodynamics: II. Ritonavir effects on CYP3A and P-glycoprotein activities

1 reference

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Gender has a small but statistically significant effect on clearance of CYP3A substrate drugs

1 reference

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27 May 2018

New era in drug interaction evaluation: US Food and Drug Administration update on CYP enzymes, transporters, and the guidance process

1 reference

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Drug interaction studies: study design, data analysis, and implications for dosing and labeling

1 reference

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Effect of widely used combinations of antiretroviral therapy on liver CYP3A4 activity in HIV-infected patients.

1 reference

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27 May 2018

Stochastic prediction of CYP3A-mediated inhibition of midazolam clearance by ketoconazole

1 reference

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27 May 2018

The utility of in vitro cytochrome P450 inhibition data in the prediction of drug-drug interactions

1 reference

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CYP3A4 substrate selection and substitution in the prediction of potential drug-drug interactions

1 reference

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Organoselenium and organotellurium compounds: toxicology and pharmacology

1 reference

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27 May 2018

Role of hepatic and intestinal cytochrome P450 3A and 2B6 in the metabolism, disposition, and miotic effects of methadone

1 reference

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27 May 2018

Exposure-dependent inhibition of intestinal and hepatic CYP3A4 in vivo by grapefruit juice

1 reference

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27 May 2018

Time course of recovery of cytochrome p450 3A function after single doses of grapefruit juice

1 reference

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The Conduct of In Vitro and In Vivo Drug-Drug Interaction Studies: A PhRMA Perspective

1 reference

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Short-term exposure to low-dose ritonavir impairs clearance and enhances adverse effects of trazodone.

1 reference

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27 May 2018

Intestinal first pass metabolism of midazolam in liver cirrhosis --effect of grapefruit juice

1 reference

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27 May 2018

Optimizing drug development: strategies to assess drug metabolism/transporter interaction potential--towards a consensus

1 reference

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Pharmacokinetic interactions between sildenafil and saquinavir/ritonavir

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27 May 2018

Phenotyping of drug-metabolizing enzymes in adults: a review of in-vivo cytochrome P450 phenotyping probes

1 reference

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ABT-378, a highly potent inhibitor of the human immunodeficiency virus protease

1 reference

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27 May 2018

Differential inhibition of cytochrome P450 isoforms by the protease inhibitors, ritonavir, saquinavir and indinavir

1 reference

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27 May 2018

Saquinavir pharmacokinetics alone and in combination with ritonavir in HIV-infected patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810804

27 May 2018

Pharmacokinetic enhancement of inhibitors of the human immunodeficiency virus protease by coadministration with ritonavir.

1 reference

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27 May 2018

Midazolam hydroxylation by human liver microsomes in vitro: inhibition by fluoxetine, norfluoxetine, and by azole antifungal agents.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810804

27 May 2018

Oxidation of midazolam and triazolam by human liver cytochrome P450IIIA4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810804

27 May 2018

Ritonavir greatly impairs CYP3A activity in HIV infection with chronic viral hepatitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810804

16 August 2018

Dose-response of ritonavir on hepatic CYP3A activity and elvitegravir oral exposure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810804

16 August 2018

Effect of an antiretroviral regimen containing ritonavir boosted lopinavir on intestinal and hepatic CYP3A, CYP2D6 and P-glycoprotein in HIV-infected patients

1 reference

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16 August 2018

Pomegranate juice does not impair clearance of oral or intravenous midazolam, a probe for cytochrome P450-3A activity: comparison with grapefruit juice.

1 reference

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Haptoglobin genotype determines myocardial infarct size in diabetic mice

1 reference

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16 August 2018

Lopinavir/ritonavir induces the hepatic activity of cytochrome P450 enzymes CYP2C9, CYP2C19, and CYP1A2 but inhibits the hepatic and intestinal activity of CYP3A as measured by a phenotyping drug cocktail in healthy volunteers.

1 reference

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16 August 2018

Comparison of midazolam and simvastatin as cytochrome P450 3A probes.

1 reference

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Effect of extended exposure to grapefruit juice on cytochrome P450 3A activity in humans: comparison with ritonavir

1 reference

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Differential inhibition of cytochrome P450 3A4, 3A5 and 3A7 by five human immunodeficiency virus (HIV) protease inhibitors in vitro

1 reference

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Variations of CYP3A activity induced by antiretroviral treatment in HIV-1 infected patients

1 reference

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Oral administration of a low dose of midazolam (75 microg) as an in vivo probe for CYP3A activity

1 reference

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An evaluation of the suitability of intravenous midazolam as an in vivo marker for hepatic cytochrome P4503A activity

1 reference

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Application of semisimultaneous midazolam administration for hepatic and intestinal cytochrome P450 3A phenotyping

1 reference

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Differential impairment of triazolam and zolpidem clearance by ritonavir

1 reference

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Midazolam and triazolam biotransformation in mouse and human liver microsomes: relative contribution of CYP3A and CYP2C isoforms.

1 reference

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Concurrent administration of the erythromycin breath test (EBT) and oral midazolam as in vivo probes for CYP3A activity.

1 reference

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16 August 2018

Differentiation of intestinal and hepatic cytochrome P450 3A activity with use of midazolam as an in vivo probe: effect of ketoconazole.

1 reference

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Analysis of ritonavir in plasma/serum and tissues by high-performance liquid chromatography

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The contribution of intestinal and hepatic CYP3A to the interaction between midazolam and clarithromycin.

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ICAM-1 and VCAM-1 expression induced by TNF-alpha are inhibited by a glutathione peroxidase mimic

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Interaction between grapefruit juice and midazolam in humans*

1 reference

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Effect of age, gender, and obesity on midazolam kinetics.

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Alprazolam-ritonavir interaction: implications for product labeling

1 reference

https://pubmed.ncbi.nlm.nih.gov/20002087

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potent mechanism-based inhibition of human CYP3A in vitro by amprenavir and ritonavir: comparison with ketoconazole

1 reference

https://pubmed.ncbi.nlm.nih.gov/20002087

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Shear stress induces iNOS expression in cultured smooth muscle cells: role of oxidative stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/20002087

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protease inhibitors as inhibitors of human cytochromes P450: high risk associated with ritonavir

1 reference

https://pubmed.ncbi.nlm.nih.gov/20002087

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preparation of scientific reports on pharmacokinetic drug interaction studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/20002087

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inferred from PubMed ID database lookup

Identifiers

10.1111/J.1365-2125.2009.03545.X

1 reference

Europe PubMed Central

PMC publication ID

11 November 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 November 2017

ResearchGate publication ID

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