(Q37256195)

19 August 2017

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title

Gender has a small but statistically significant effect on clearance of CYP3A substrate drugs (English)

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19 August 2017

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1

David J Greenblatt

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19 August 2017

2

Lisa L von Moltke

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19 August 2017

publication date

29 August 2008

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The Journal of Clinical Pharmacology

19 August 2017

published in

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19 August 2017

volume

48

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19 August 2017

issue

11

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19 August 2017

page(s)

1350-1355

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Gender in the pharmacy: does it matter?

19 August 2017

cites work

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https://api.crossref.org/works/10.1177%2F0091270008323754

Cytochrome P-450 3A4: regulation and role in drug metabolism

21 January 2018

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Human variability in CYP3A4 metabolism and CYP3A4-related uncertainty factors for risk assessment

21 January 2018

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Cytochrome P4503A (CYP3A) metabolism: prediction of in vivo activity in humans

21 January 2018

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Cytochrome P450 3A and their regulation

21 January 2018

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Gender differences in pharmacokinetics and pharmacodynamics of psychotropic medication

21 January 2018

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https://api.crossref.org/works/10.1177%2F0091270008323754

Gender effects in pharmacokinetics and pharmacodynamics

21 January 2018

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https://api.crossref.org/works/10.1177%2F0091270008323754

Gender differences in pharmacokinetics

21 January 2018

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https://api.crossref.org/works/10.1177%2F0091270008323754

Sex-dependent metabolism of xenobiotics.

21 January 2018

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https://api.crossref.org/works/10.1177%2F0091270008323754

Drugs and sex differences: a review of drugs relating to anaesthesia

21 January 2018

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https://api.crossref.org/works/10.1177%2F0091270008323754

21 January 2018

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https://api.crossref.org/works/10.1177%2F0091270008323754

How important are gender differences in pharmacokinetics?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270008323754

Gender differences in drug effects: implications for anesthesiologists

21 January 2018

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https://api.crossref.org/works/10.1177%2F0091270008323754

The influence of sex on pharmacokinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270008323754

Sex differences in pharmacokinetics and pharmacodynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270008323754

The influence of age and sex on the clearance of cytochrome P450 3A substrates

21 January 2018

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https://api.crossref.org/works/10.1177%2F0091270008323754

Confounding factors for sex differences in pharmacokinetics and pharmacodynamics: focus on dosing regimen, dosage form, and formulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270008323754

Sex and racial differences in pharmacological response: where is the evidence? Pharmacogenetics, pharmacokinetics, and pharmacodynamics

21 January 2018

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The current state of knowledge on age, sex, and their interactions on clinical pharmacology

21 January 2018

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https://api.crossref.org/works/10.1177%2F0091270008323754

Sex-specific differences in CYP450 isoforms in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270008323754

Bioequivalence revisited: influence of age and sex on CYP enzymes

21 January 2018

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https://api.crossref.org/works/10.1177%2F0091270008323754

The distribution and gender difference of CYP3A activity in Chinese subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270008323754

The contribution of intestinal and hepatic CYP3A to the interaction between midazolam and clarithromycin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270008323754

The effect of age, sex, and rifampin administration on intestinal and hepatic cytochrome P450 3A activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270008323754

Differentiation of intestinal and hepatic cytochrome P450 3A activity with use of midazolam as an in vivo probe: effect of ketoconazole.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270008323754

Effect of age and gender on the activity of human hepatic CYP3A

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270008323754

Interindividual variability in catalytic activity and immunoreactivity of three major human liver cytochrome P450 isozymes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270008323754

The effects of gender, age, ethnicity, and liver cirrhosis on cytochrome P450 enzyme activity in human liver microsomes and inducibility in cultured human hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270008323754

Factors influencing midazolam hydroxylation activity in human liver microsomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270008323754

Do men and women differ in proximal small intestinal CYP3A or P-glycoprotein expression?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270008323754

Sex is a major determinant of CYP3A4 expression in human liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270008323754

21 January 2018

Identifiers

DOI

10.1177/0091270008323754

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19 August 2017

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