(Q42949861)

English

Validation and pharmacological characterisation of MK-801-induced locomotor hyperactivity in BALB/C mice as an assay for detection of novel antipsychotics

scientific article published on July 31, 2010

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

11 November 2017

Validation and pharmacological characterisation of MK-801-induced locomotor hyperactivity in BALB/C mice as an assay for detection of novel antipsychotics (English)

1 reference

Europe PubMed Central

PubMed publication ID

11 November 2017

1 reference

based on heuristic

inferred from title

author name string

Mikhail Kalinichev

4

1 reference

Europe PubMed Central

PubMed publication ID

11 November 2017

Andrea M. Bradford

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20676613

14 June 2024

Kevin M. Savage

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20676613

14 June 2024

Declan N. C. Jones

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20676613

14 June 2024

language of work or name

1 reference

National Center for Biotechnology Information

PubMed publication ID

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20676613

14 June 2024

publication date

31 July 2010

1 reference

Europe PubMed Central

PubMed publication ID

11 November 2017

full work available at URL

http://link.springer.com/content/pdf/10.1007/s00213-010-1938-0.pdf

Portable Document Format

1 reference

10.1007/S00213-010-1938-0

https://api.crossref.org/works/10.1007/S00213-010-1938-0

14 June 2024

http://link.springer.com/article/10.1007/s00213-010-1938-0/fulltext.html

1 reference

10.1007/S00213-010-1938-0

https://api.crossref.org/works/10.1007/S00213-010-1938-0

14 June 2024

http://link.springer.com/content/pdf/10.1007/s00213-010-1938-0

1 reference

10.1007/S00213-010-1938-0

https://api.crossref.org/works/10.1007/S00213-010-1938-0

14 June 2024

Psychopharmacology

1 reference

Europe PubMed Central

PubMed publication ID

11 November 2017

212

1 reference

Europe PubMed Central

PubMed publication ID

11 November 2017

2

1 reference

Europe PubMed Central

PubMed publication ID

11 November 2017

155-170

1 reference

Europe PubMed Central

PubMed publication ID

11 November 2017

https://scigraph.springernature.com/pub.10.1007/s00213-010-1938-0

0 references

Recent advances in the phencyclidine model of schizophrenia

1 reference

https://api.crossref.org/works/10.1007%2FS00213-010-1938-0

21 January 2018

Characterization of MDL 73005EF as a 5-HT1A selective ligand and its effects in animal models of anxiety: comparison with buspirone, 8-OH-DPAT and diazepam

1 reference

https://api.crossref.org/works/10.1007%2FS00213-010-1938-0

21 January 2018

Glutamate receptor dysfunction and schizophrenia

1 reference

https://api.crossref.org/works/10.1007%2FS00213-010-1938-0

21 January 2018

The dopamine hypothesis of schizophrenia: focus on the dopamine receptor

1 reference

https://api.crossref.org/works/10.1007%2FS00213-010-1938-0

21 January 2018

Pharmacological actions of a novel, high-affinity, and selective human dopamine D(3) receptor antagonist, SB-277011-A

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The metabotropic glutamate 2/3 receptor agonists LY354740 and LY379268 selectively attenuate phencyclidine versus d-amphetamine motor behaviors in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Effects of dizocilpine and phencyclidine on prepulse inhibition of the acoustic startle reflex and on prepulse-elicited reactivity in C57BL6 mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Repeated administration of phencyclidine, amphetamine and MK-801 selectively impairs spatial learning in mice: a possible model of psychotomimetic drug-induced cognitive deficits

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preferential inhibition of dizocilpine-induced hyperlocomotion by olanzapine

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A single application of MK801 causes symptoms of acute psychosis, deficits in spatial memory, and impairment of synaptic plasticity in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

N-methyl-D-aspartate receptor antagonists enhance histamine neuron activity in rodent brain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MK-801, a proposed noncompetitive antagonist of excitatory amino acid neurotransmission, produces phencyclidine-like behavioral effects in pigeons, rats and rhesus monkeys

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reversal of phencyclidine effects by a group II metabotropic glutamate receptor agonist in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thioperamide, the selective histamine H3 receptor antagonist, attenuates stimulant-induced locomotor activity in the mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of dopamine receptor antagonists on hyperlocomotion induced by cocaine, amphetamine, MK-801 and the dopamine D1 agonist C-APB in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of apomorphine, amphetamine and dizocilpine disruptions of prepulse inhibition in inbred and outbred mice strains

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GABAergic dysfunction in schizophrenia: new treatment strategies on the horizon.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Xanomeline, an M(1)/M(4) preferring muscarinic cholinergic receptor agonist, produces antipsychotic-like activity in rats and mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective muscarinic receptor agonist xanomeline as a novel treatment approach for schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of dopamine D1 and D2 receptor blockade on MK-801-induced hyperlocomotion in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of aripiprazole/OPC-14597 on motor activity, pharmacological models of psychosis, and brain activity in rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The muscarinic receptor agonist xanomeline has an antipsychotic-like profile in the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The antipsychotic potential of l-stepholidine--a naturally occurring dopamine receptor D1 agonist and D2 antagonist

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Strain-specificity in nicotine attenuation of phencyclidine-induced disruption of prepulse inhibition in mice: relevance to smoking in schizophrenia patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lack of effect of LY314582 (a group 2 metabotropic glutamate receptor agonist) on phencyclidine-induced locomotor activity in metabotropic glutamate receptor 2 knockout mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of nucleus accumbens dopamine in the neurochemical and behavioral effects of phencyclidine: a microdialysis and behavioral study

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diazepam treatment of early signs of exacerbation in schizophrenia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A selective allosteric potentiator of metabotropic glutamate (mGlu) 2 receptors has effects similar to an orthosteric mGlu2/3 receptor agonist in mouse models predictive of antipsychotic activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Strain-specific effects of amphetamine on prepulse inhibition and patterns of locomotor behavior in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of phencyclidine (PCP) and (+)MK-801 on sensorimotor gating in CD-1 mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: a randomized Phase 2 clinical trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effects of ketamine vary among inbred mouse strains and mimic schizophrenia for the P80, but not P20 or N40 auditory ERP components

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antipsychotic agents antagonize non-competitive N-methyl-D-aspartate antagonist-induced behaviors

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Histamine metabolites in cerebrospinal fluid of patients with chronic schizophrenia: their relationships to levels of other aminergic transmitters and ratings of symptoms

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of the H3 receptor inverse agonist thioperamide on cocaine-induced locomotion in mice: role of the histaminergic system and potential pharmacokinetic interactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of MK-801-induced behavior as a putative rat model of psychosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biphasic effects of clonidine on conflict behavior: involvement of different alpha-adrenoceptors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anxiolytic and sedative effects of 5-HT1A ligands, 8-OH-DPAT and MDL 73005EF, in mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immediate and long-lasting effects of MK-801 on motor activity, spatial navigation in a swimming pool and EEG in the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glycine and D-serine decrease MK-801-induced hyperactivity in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The behavioral and neurochemical effects of phencyclidine in humans and animals: some implications for modeling psychosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mGlu2 but not the mGlu3 receptor mediates the actions of the mGluR2/3 agonist, LY379268, in mouse models predictive of antipsychotic activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interactive effects of subanesthetic ketamine and haloperidol in healthy humans.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Histamine and schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Attenuation of amphetamine-induced activity by the non-selective muscarinic receptor agonist, xanomeline, is absent in muscarinic M4 receptor knockout mice and attenuated in muscarinic M1 receptor knockout mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Behavioral effects of MK-801 in the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The behavioural effects of MK-801: a comparison with antagonists acting non-competitively and competitively at the NMDA receptor.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inbred mouse strains differ in sensitivity to "popping" behavior elicited by MK-801

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Locomotor reactivity to a novel environment and sensitivity to MK-801 in five strains of mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute and chronic phencyclidine effects on locomotor activity, stereotypy and ataxia in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aripiprazole, an atypical antipsychotic, prevents the motor hyperactivity induced by psychotomimetics and psychostimulants in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The glutamatergic dysfunction hypothesis for schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phencyclidine-induced stereotype in rats: effects of methadone, apomorphine, and naloxone

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel selective allosteric activator of the M1 muscarinic acetylcholine receptor regulates amyloid processing and produces antipsychotic-like activity in rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inbred mouse strains differ in their sensitivity to an antiseizure effect of MK-801.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The dopamine D3 receptor mediates locomotor hyperactivity induced by NMDA receptor blockade

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preclinical investigations into the antipsychotic potential of the novel histamine H3 receptor antagonist GSK207040.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The neuropsychopharmacology of phencyclidine: from NMDA receptor hypofunction to the dopamine hypothesis of schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of the H(3) antagonist, thioperamide, on behavioral alterations induced by systemic MK-801 administration in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mGlu(2/3) receptor agonist LY379268 selectively blocks amphetamine ambulations and rearing

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Allosteric modulation of the muscarinic M4 receptor as an approach to treating schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Behavioral characterization of mice lacking histamine H(3) receptors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

5-HT2 receptor antagonism reduces hyperactivity induced by amphetamine, cocaine, and MK-801 but not D1 agonist C-APB

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The topography of MK-801-induced locomotor patterns in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Low cerebrospinal fluid glutamate in schizophrenic patients and a new hypothesis on schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of caffeine in animal models of learning and memory

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Do NMDA receptor antagonist models of schizophrenia predict the clinical efficacy of antipsychotic drugs?

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The glycine transporter-1 inhibitor SSR103800 displays a selective and specific antipsychotic-like profile in normal and transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Atypical antipsychotics clozapine and quetiapine attenuate prepulse inhibition deficits in dopamine transporter knockout mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of NR1, NR2A and NR2B NMDA receptor subunits is not altered in the genetically-inbred Balb/c mouse strain with heightened behavioral sensitivity to MK-801, a noncompetitive NMDA receptor antagonist

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute and chronic effects of methamphetamine on tele-methylhistamine levels in mouse brain: selective involvement of the D(2) and not D(3) receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel NMDA antagonist, MK-801, impairs performance in a hippocampal-dependent spatial learning task.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Highly potent and selective ligands for histamine H3-receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Seroquel: biochemical profile of a potential atypical antipsychotic.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of risperidone on phencyclidine-induced behaviors: comparison with haloperidol and ritanserin

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MK-801 and AP5 impair acquisition, but not retention, of the Morris milk maze

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blockade of phencyclidine-induced hyperlocomotion by clozapine and MDL 100,907 in rats reflects antagonism of 5-HT2A receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aripiprazole increases dopamine but not noradrenaline and serotonin levels in the mouse prefrontal cortex

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hyperactivity, hyper-reactivity, and sensorimotor deficits induced by low doses of the N-methyl-D-aspartate non-competitive channel blocker MK801

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Centrally active allosteric potentiators of the M4 muscarinic acetylcholine receptor reverse amphetamine-induced hyperlocomotor activity in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Home cage activity and behavioral performance in inbred and hybrid mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Risperidone attenuates MK-801-induced hyperlocomotion in mice via the blockade of serotonin 5-HT 2A/2C receptors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of metabotropic glutamate receptors as a novel approach for the treatment of schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/20676613

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

European Journal of Pharmacology

12

361

39

author name string

J Cartmell

publication date

2000

1 reference

10.1007/S00213-010-1938-0

https://api.crossref.org/works/10.1007/S00213-010-1938-0

14 June 2024

Identifiers

10.1007/S00213-010-1938-0

1 reference

Europe PubMed Central

PubMed publication ID

11 November 2017

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

11 November 2017

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