(Q43037326)

12 November 2017

title

High resolution footprinting of the hepatitis C virus polymerase NS5B in complex with RNA. (English)

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12 November 2017

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7

Mamuka Kvaratskhelia

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12 November 2017

6

Sonja Hess

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12 November 2017

Jérôme Deval

1

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12 November 2017

Claudia M D'Abramo

2

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12 November 2017

Zhuojun Zhao

3

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12 November 2017

Suzanne McCormick

4

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12 November 2017

Dimitrios Coutsinos

5

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12 November 2017

Matthias Götte

8

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12 November 2017

language of work or name

English

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publication date

18 April 2007

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Journal of Biological Chemistry

12 November 2017

published in

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12 November 2017

volume

282

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12 November 2017

issue

23

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12 November 2017

page(s)

16907-16916

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Epidemiology of hepatitis C: geographic differences and temporal trends

12 November 2017

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Template/primer requirements and single nucleotide incorporation by hepatitis C virus nonstructural protein 5B polymerase

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Multiple interactions within the hepatitis C virus RNA polymerase repress primer-dependent RNA synthesis

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A novel mechanism to ensure terminal initiation by hepatitis C virus NS5B polymerase

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Crystal structure of the RNA-dependent RNA polymerase of hepatitis C virus

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Crystal structure of the RNA-dependent RNA polymerase from hepatitis C virus reveals a fully encircled active site

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Structural Analysis of the Hepatitis C Virus RNA Polymerase in Complex with Ribonucleotides

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Mutagenesis analysis of the rGTP-specific binding site of hepatitis C virus RNA-dependent RNA polymerase

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De novo initiation pocket mutations have multiple effects on hepatitis C virus RNA-dependent RNA polymerase activities

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Substrate complexes of hepatitis C virus RNA polymerase (HC-J4): structural evidence for nucleotide import and de-novo initiation

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Interactions of HIV-1 Gag with assembly cofactors

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Modulation of replication protein A function by its hyperphosphorylation-induced conformational change involving DNA binding domain B.

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Ribonuclease H. An Enzyme Degrading the RNA Moiety of DNA-RNA Hybrids

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Requirements for De Novo Initiation of RNA Synthesis by Recombinant Flaviviral RNA-Dependent RNA Polymerases

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Crystal structures of RNase H bound to an RNA/DNA hybrid: substrate specificity and metal-dependent catalysis

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Mass spectrometric identification of lysines involved in the interaction of human replication protein a with single-stranded DNA.

21 January 2018

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Identification of specific HIV-1 reverse transcriptase contacts to the viral RNA:tRNA complex by mass spectrometry and a primary amine selective reagent

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Excision of incorporated nucleotide analogue chain-terminators can diminish their inhibitory effects on viral RNA-dependent RNA polymerases

21 January 2018

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De novo initiation of RNA synthesis by the RNA-dependent RNA polymerase (NS5B) of hepatitis C virus

21 January 2018

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The polymerase subunit of a dsRNA virus plays a central role in the regulation of viral RNA metabolism

21 January 2018

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A mechanism for initiating RNA-dependent RNA polymerization

21 January 2018

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Biochemical properties of full-length hepatitis C virus RNA-dependent RNA polymerase expressed in insect cells

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In vitro RNA replication directed by replicase complexes isolated from the subgenomic replicon cells of hepatitis C virus

21 January 2018

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Modulation of the hepatitis C virus RNA-dependent RNA polymerase activity by the non-structural (NS) 3 helicase and the NS4B membrane protein.

21 January 2018

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Functional analysis of RNA binding by the hepatitis C virus RNA-dependent RNA polymerase

21 January 2018

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A structural and primary sequence comparison of the viral RNA-dependent RNA polymerases

21 January 2018

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Modulation of hepatitis C virus RNA-dependent RNA polymerase activity by structure-based site-directed mutagenesis

21 January 2018

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Direct interaction between nucleolin and hepatitis C virus NS5B

21 January 2018

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Oligomeric interaction of hepatitis C virus NS5B is critical for catalytic activity of RNA-dependent RNA polymerase

21 January 2018

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Crystal structures of the RNA-dependent RNA polymerase genotype 2a of hepatitis C virus reveal two conformations and suggest mechanisms of inhibition by non-nucleoside inhibitors

21 January 2018

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Non-nucleoside inhibitors binding to hepatitis C virus NS5B polymerase reveal a novel mechanism of inhibition

21 January 2018

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Interdomain communication in hepatitis C virus polymerase abolished by small molecule inhibitors bound to a novel allosteric site

21 January 2018

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Crystal structure of HIV-1 reverse transcriptase in complex with a polypurine tract RNA:DNA

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M701973200

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12 November 2017

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