(Q43116152)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20349222%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

title

Sustained production of spliced X-box binding protein 1 (XBP1) induces pancreatic beta cell dysfunction and apoptosis (English)

1 reference

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29 January 2020

1

1 reference

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29 January 2020

Fernanda Ortis

3

1 reference

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29 January 2020

Stephan Lortz

5

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29 January 2020

author name string

F Christulia

2

1 reference

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29 January 2020

P Pirot

4

1 reference

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29 January 2020

S Lenzen

6

1 reference

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29 January 2020

D L Eizirik

7

1 reference

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29 January 2020

A K Cardozo

8

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29 January 2020

publication date

29 March 2010

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29 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20349222%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

volume

53

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29 January 2020

issue

6

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29 January 2020

page(s)

1120-1130

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https://scigraph.springernature.com/pub.10.1007/s00125-010-1699-7

29 January 2020

exact match

0 references

cites work

XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein Response

1 reference

12 December 2020

Glucose regulation of insulin gene expression in pancreatic beta-cells

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12 December 2020

Inhibition of cytokine-induced NF-kappaB activation by adenovirus-mediated expression of a NF-kappaB super-repressor prevents beta-cell apoptosis

1 reference

12 December 2020

Global profiling of genes modified by endoplasmic reticulum stress in pancreatic beta cells reveals the early degradation of insulin mRNAs

1 reference

12 December 2020

Cytokines downregulate the sarcoendoplasmic reticulum pump Ca2+ ATPase 2b and deplete endoplasmic reticulum Ca2+, leading to induction of endoplasmic reticulum stress in pancreatic beta-cells

1 reference

12 December 2020

Interferon-gamma potentiates endoplasmic reticulum stress-induced death by reducing pancreatic beta cell defence mechanisms

1 reference

12 December 2020

Functional significance of repressor element 1 silencing transcription factor (REST) target genes in pancreatic beta cells.

1 reference

12 December 2020

XBP-1 is required for biogenesis of cellular secretory machinery of exocrine glands

1 reference

12 December 2020

Transcriptional regulation of the endoplasmic reticulum stress gene chop in pancreatic insulin-producing cells

1 reference

12 December 2020

The role of IRE1alpha in the degradation of insulin mRNA in pancreatic beta-cells

1 reference

12 December 2020

XBP1 is critical to protect cells from endoplasmic reticulum stress: evidence from Site-2 protease-deficient Chinese hamster ovary cells.

1 reference

12 December 2020

The role for endoplasmic reticulum stress in diabetes mellitus

1 reference

12 December 2020

Toll-like receptor 3 and STAT-1 contribute to double-stranded RNA+ interferon-gamma-induced apoptosis in primary pancreatic beta-cells

1 reference

12 December 2020

XBP1 is essential for survival under hypoxic conditions and is required for tumor growth.

1 reference

12 December 2020

Transcriptional induction of mammalian ER quality control proteins is mediated by single or combined action of ATF6alpha and XBP1

1 reference

12 December 2020

Induction of nuclear factor-kappaB and its downstream genes by TNF-alpha and IL-1beta has a pro-apoptotic role in pancreatic beta cells

1 reference

12 December 2020

Unfolded protein response transcription factor XBP-1 does not influence prion replication or pathogenesis.

1 reference

12 December 2020

Preventing oxidative stress: a new role for XBP1.

1 reference

12 December 2020

Glucose stimulates proinsulin biosynthesis by a dose-dependent recruitment of pancreatic beta cells

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12 December 2020

Initiation and execution of lipotoxic ER stress in pancreatic beta-cells

1 reference

12 December 2020

XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor

1 reference

12 December 2020

Mitochondrial membrane permeabilization in cell death

1 reference

12 December 2020

Unconventional splicing of XBP-1 mRNA in the unfolded protein response

1 reference

12 December 2020

Expression of neuronal traits in pancreatic beta cells. Implication of neuron-restrictive silencing factor/repressor element silencing transcription factor, a neuron-restrictive silencer.

1 reference

12 December 2020

Identification of novel cytokine-induced genes in pancreatic beta-cells by high-density oligonucleotide arrays

1 reference

12 December 2020

Nitric oxide-induced apoptosis in pancreatic beta cells is mediated by the endoplasmic reticulum stress pathway

1 reference

12 December 2020

Selective inhibition of eukaryotic translation initiation factor 2 alpha dephosphorylation potentiates fatty acid-induced endoplasmic reticulum stress and causes pancreatic beta-cell dysfunction and apoptosis

1 reference

12 December 2020

Oligonucleotide microarray analysis reveals PDX1 as an essential regulator of mitochondrial metabolism in rat islets

1 reference

12 December 2020

Glucose regulated proteins 78 protects insulinoma cells (NIT-1) from death induced by streptozotocin, cytokines or cytotoxic T lymphocytes

1 reference

12 December 2020

The role of nitric oxide and the unfolded protein response in cytokine-induced beta-cell death

1 reference

12 December 2020

Regulation by cytokines of the inducible nitric oxide synthase promoter in insulin-producing cells

1 reference

12 December 2020

A new in vitro model for the study of pancreatic A and B cells

1 reference

12 December 2020

The role of inflammation in insulitis and beta-cell loss in type 1 diabetes

1 reference

12 December 2020

A simplified system for generating recombinant adenoviruses

1 reference

12 December 2020

IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA

1 reference

12 December 2020

An essential role in liver development for transcription factor XBP-1

1 reference

12 December 2020

The loss of GLUT2 expression by glucose-unresponsive beta cells of db/db mice is reversible and is induced by the diabetic environment

1 reference

12 December 2020

A comprehensive analysis of cytokine-induced and nuclear factor-kappa B-dependent genes in primary rat pancreatic beta-cells

1 reference

12 December 2020

High expression rates of human islet amyloid polypeptide induce endoplasmic reticulum stress mediated beta-cell apoptosis, a characteristic of humans with type 2 but not type 1 diabetes

1 reference

12 December 2020

Endoplasmic reticulum stress-induced activation of activating transcription factor 6 decreases insulin gene expression via up-regulation of orphan nuclear receptor small heterodimer partner

1 reference

12 December 2020

Cytokine-induced beta-cell death is independent of endoplasmic reticulum stress signaling.

1 reference

12 December 2020

Glucose promotes survival of rat pancreatic beta cells by activating synthesis of proteins which suppress a constitutive apoptotic program

1 reference

12 December 2020

Insulin protects islets from apoptosis via Pdx1 and specific changes in the human islet proteome

1 reference

12 December 2020

Plasma cell differentiation and the unfolded protein response intersect at the transcription factor XBP-1

1 reference

12 December 2020

IRE1alpha kinase activation modes control alternate endoribonuclease outputs to determine divergent cell fates.

1 reference

12 December 2020

Protective effect against Parkinson's disease-related insults through the activation of XBP1

1 reference

12 December 2020

Cytokine-induced proapoptotic gene expression in insulin-producing cells is related to rapid, sustained, and nonoscillatory nuclear factor-kappaB activation

1 reference

12 December 2020

Regulation of insulin gene transcription

1 reference

12 December 2020

PDX-1 and MafA play a crucial role in pancreatic beta-cell differentiation and maintenance of mature beta-cell function

1 reference

12 December 2020

Differential contributions of ATF6 and XBP1 to the activation of endoplasmic reticulum stress-responsive cis-acting elements ERSE, UPRE and ERSE-II

1 reference

12 December 2020