(Q43150268)

14 November 2017

title

Synthesis of 3'-amino-3'-deoxyguanosine and 3'-amino-3'-deoxyxyloguanosine monophosphate HepDirect prodrugs from guanosine (English)

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14 November 2017

Brett C Bookser

1

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14 November 2017

Nicholas B Raffaele

2

1 reference

14 November 2017

K Raja Reddy

3

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14 November 2017

Kevin Fan

4

1 reference

14 November 2017

Wenjian Huang

5

1 reference

14 November 2017

Mark D Erion

6

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14 November 2017

publication date

1 October 2009

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Nucleosides, Nucleotides & Nucleic Acids

14 November 2017

published in

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14 November 2017

volume

28

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14 November 2017

issue

10

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14 November 2017

page(s)

969-986

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https://api.crossref.org/works/10.1080%2F15257770903307151

14 November 2017

1 reference

2',3'-Bis(2-chloroethyl)aminophosphoryl-3'-amino-3'-deoxyadenosine: a cyclic nucleotide with antitumor activity

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1 reference

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Syntheses of puromycin from adenosine and 7-deazapuromycin from tubercidin, and biological comparisons of the 7-aza/deaza pair

21 January 2018

1 reference

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A practical route to 3'-amino-3'-deoxyadenosine derivatives and puromycin analogues

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15257770903307151

Azidonucleosides: synthesis, reactions, and biological properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15257770903307151

N6-cyclopentyl-3'-substituted-xylofuranosyladenosines: a new class of non-xanthine adenosine A1 receptor antagonists.

21 January 2018

1 reference

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Neoceptor concept based on molecular complementarity in GPCRs: a mutant adenosine A(3) receptor with selectively enhanced affinity for amine-modified nucleosides

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1 reference

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Orthogonal activation of the reengineered A3 adenosine receptor (neoceptor) using tailored nucleoside agonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15257770903307151

Improved and reliable synthesis of 3'-azido-2',3'-dideoxyguanosine derivatives

21 January 2018

1 reference

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Synthesis and anti-HIV activity of beta-D-3'-azido-2',3'-unsaturated nucleosides and beta-D-3'-azido-3'-deoxyribofuranosylnucleosides

21 January 2018

1 reference

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Telomere shortening in human HL60 cells by treatment with 3'-azido-2',3'-dideoxynucleosides and telomerase inhibition by their 5'-triphosphates

21 January 2018

1 reference

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Structure-activity relationship of purine ribonucleosides for inhibition of hepatitis C virus RNA-dependent RNA polymerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15257770903307151

Structure-activity relationship of heterobase-modified 2'-C-methyl ribonucleosides as inhibitors of hepatitis C virus RNA replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15257770903307151

A 7-deaza-adenosine analog is a potent and selective inhibitor of hepatitis C virus replication with excellent pharmacokinetic properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15257770903307151

Synthesis and evaluation of S-acyl-2-thioethyl esters of modified nucleoside 5'-monophosphates as inhibitors of hepatitis C virus RNA replication.

21 January 2018

1 reference

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Characterization of resistance to non-obligate chain-terminating ribonucleoside analogs that inhibit hepatitis C virus replication in vitro

21 January 2018

1 reference

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Development and optimization of anti-HIV nucleoside analogs and prodrugs: A review of their cellular pharmacology, structure-activity relationships and pharmacokinetics

21 January 2018

1 reference

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Design, synthesis, and characterization of a series of cytochrome P(450) 3A-activated prodrugs (HepDirect prodrugs) useful for targeting phosph(on)ate-based drugs to the liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15257770903307151

Prodrugs of phosphates and phosphonates

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15257770903307151

Remofovir mesylate: a prodrug of PMEA with improved liver-targeting and safety in rats and monkeys

21 January 2018

1 reference

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Liver-targeted drug delivery using HepDirect prodrugs

21 January 2018

1 reference

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Pradefovir: a prodrug that targets adefovir to the liver for the treatment of hepatitis B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15257770903307151

Targeting thyroid hormone receptor-beta agonists to the liver reduces cholesterol and triglycerides and improves the therapeutic index

21 January 2018

1 reference

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Synthesis and biological evaluation of a series of liver-selective phosphonic acid thyroid hormone receptor agonists and their prodrugs

21 January 2018

1 reference

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Inhibitory Effect of 2'-Substituted Nucleosides on Hepatitis C Virus Replication Correlates with Metabolic Properties in Replicon Cells

21 January 2018

1 reference

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21 January 2018

1 reference

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Nucleotide chemistry. XX. Use of the azido group in the synthesis of 5'-terminal aminodeoxythymidine oligonucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15257770903307151

Liver-targeted prodrugs of 2'-C-methyladenosine for therapy of hepatitis C virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15257770903307151

Polymer-assisted solution-phase synthesis of 2'-amido-2'-deoxyadenosine derivatives targeted at the NAD(+)-binding sites of parasite enzymes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15257770903307151

Synthesis of 9-(3-azido-2,3-dideoxy-β-D--pentofuranosyl)-2,6-diaminopurine (AzddDAP)

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15257770903307151

Synthesis and Conformational Analysis of 2?-Deoxy-2?-(3-methoxybenzamido)adenosine, a rational-designed inhibitor of trypanosomal glyceraldehyde phosphate dehydrogenase (GAPDH)

21 January 2018

1 reference

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10.1080/15257770903307151

21 January 2018

Identifiers

DOI

1 reference

14 November 2017

1 reference