(Q43211428)

16 November 2017

title

The genetic and metabolic signature of oncocytic transformation implicates HIF1alpha destabilization (English)

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Mariantonietta Capristo

Mariantonietta Capristo

6

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Michela Rugolo

Michela Rugolo

17

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Valerio Carelli

Valerio Carelli

15

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Giovanni Tallini

Giovanni Tallini

13

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author name string

Anna Maria Porcelli

1

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16 November 2017

Anna Ghelli

2

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Giovanna Cenacchi

5

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16 November 2017

Lucia Fiammetta Pennisi

7

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Isabella Morra

8

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Enrica Ciccarelli

9

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Antonio Melcarne

10

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Anna Bartoletti-Stella

11

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Nunzio Salfi

12

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Marcella Attimonelli

16

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Giovanni Romeo

18

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Giuseppe Gasparre

19

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16 November 2017

publication date

22 December 2009

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16 November 2017

published in

Human Molecular Genetics

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16 November 2017

volume

19

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16 November 2017

issue

6

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16 November 2017

page(s)

1019-1032

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Mitochondrial disorders in the nervous system

16 November 2017

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Defective oxidative phosphorylation in thyroid oncocytic carcinoma is associated with pathogenic mitochondrial DNA mutations affecting complexes I and III.

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Clonal expansion of mutated mitochondrial DNA is associated with tumor formation and complex I deficiency in the benign renal oncocytoma

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Lack of complex I is associated with oncocytic thyroid tumours

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Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase

21 January 2018

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Mitochondrial dysfunction as a cause of optic neuropathies

21 January 2018

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Severe impairment of complex I-driven adenosine triphosphate synthesis in leber hereditary optic neuropathy cybrids

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Transcriptional profiling reveals coordinated up-regulation of oxidative metabolism genes in thyroid oncocytic tumors

21 January 2018

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Defective mitochondrial ATP synthesis in oxyphilic thyroid tumors.

21 January 2018

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21 January 2018

Mitochondria and cancer

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21 January 2018

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21 January 2018

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21 January 2018

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mtDNA tree Build 17 (18 Feb 2016)

21 January 2018

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Human cells lacking mtDNA: repopulation with exogenous mitochondria by complementation

21 January 2018

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The antioxidant function of Bcl-2 preserves cytoskeletal stability of cells with defective respiratory complex I.

21 January 2018

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Respiratory complex I dysfunction due to mitochondrial DNA mutations shifts the voltage threshold for opening of the permeability transition pore toward resting levels

21 January 2018

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Assessment of mitochondrial oxidative phosphorylation in patient muscle biopsies, lymphoblasts, and transmitochondrial cell lines

21 January 2018

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Differences in reactive oxygen species production explain the phenotypes associated with common mouse mitochondrial DNA variants

21 January 2018

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21 January 2018

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21 January 2018

Identifiers

DOI

10.1093/HMG/DDP566

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16 November 2017

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