(Q43221663)

16 November 2017

title

Small peptide inhibitor of JNKs protects against MPTP-induced nigral dopaminergic injury via inhibiting the JNK-signaling pathway (English)

1 reference

16 November 2017

1 reference

Jing Pan

1

1 reference

16 November 2017

Jing Qian

2

1 reference

16 November 2017

Yu Zhang

3

1 reference

16 November 2017

Jianfang Ma

4

1 reference

16 November 2017

Gang Wang

5

1 reference

16 November 2017

Qin Xiao

6

1 reference

16 November 2017

Shengdi Chen

7

1 reference

16 November 2017

Jianqing Ding

8

1 reference

16 November 2017

publication date

14 December 2009

1 reference

16 November 2017

published in

Laboratory Investigation

1 reference

16 November 2017

volume

90

1 reference

16 November 2017

issue

2

1 reference

16 November 2017

page(s)

156-167

1 reference

https://scigraph.springernature.com/pub.10.1038/labinvest.2009.124

16 November 2017

exact match

0 references

cites work

Behavioral recovery in MPTP-treated monkeys: neurochemical mechanisms studied by intrastriatal microdialysis.

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2009.124

Behavioral improvement in a primate Parkinson's model is associated with multiple homeostatic effects of human neural stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2009.124

Role of MEKK1 in cell survival and activation of JNK and ERK pathways defined by targeted gene disruption

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2009.124

JNK phosphorylates paxillin and regulates cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2009.124

Pin1 mediates neural-specific activation of the mitochondrial apoptotic machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2009.124

Benzyl isothiocyanate targets mitochondrial respiratory chain to trigger reactive oxygen species-dependent apoptosis in human breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2009.124

MAP kinases and the control of nuclear events

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2009.124

A critical role of neural-specific JNK3 for ischemic apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2009.124

JNK-mediated induction of cyclooxygenase 2 is required for neurodegeneration in a mouse model of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2009.124

Specific pathophysiological functions of JNK isoforms in the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2009.124

Notch interferes with the scaffold function of JNK-interacting protein 1 to inhibit the JNK signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2009.124

Recruitment of JNK to JIP1 and JNK-dependent JIP1 phosphorylation regulates JNK module dynamics and activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2009.124

Vaccinia virus B1R kinase interacts with JIP1 and modulates c-Jun-dependent signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2009.124

Direct inhibition of c-Jun N-terminal kinase in sympathetic neurones prevents c-jun promoter activation and NGF withdrawal-induced death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2009.124

The JNK binding domain of islet-brain 1 inhibits IL-1 induced JNK activity and apoptosis but not the transcription of key proapoptotic or protective genes in insulin-secreting cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2009.124

Identification of the critical features of a small peptide inhibitor of JNK activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2009.124

Crystal structure of JNK3: a kinase implicated in neuronal apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2009.124

Expression of FasL and its interaction with Fas are mediated by c-Jun N-terminal kinase (JNK) pathway in 6-OHDA-induced rat model of Parkinson disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2009.124

The neuroprotective effects of K252a through inhibiting MLK3/MKK7/JNK3 signaling pathway on ischemic brain injury in rat hippocampal CA1 region

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2009.124

Involvement of oxidative stress in the rapid Akt1 regulating a JNK scaffold during ischemia in rat hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2009.124

Caspase-11 mediates inflammatory dopaminergic cell death in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2009.124

Poly(ADP-ribose) polymerase activation mediates 1-methyl-4-phenyl-1, 2,3,6-tetrahydropyridine (MPTP)-induced parkinsonism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2009.124

Recombinant human granulocyte colony-stimulating factor protects against MPTP-induced dopaminergic cell death in mice by altering Bcl-2/Bax expression levels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2009.124

JNK is activated but does not mediate hippocampal neuronal apoptosis in experimental neonatal pneumococcal meningitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2009.124

The isoform-specific functions of the c-Jun N-terminal Kinases (JNKs): differences revealed by gene targeting.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2009.124

JNK2 and JNK3 combined are essential for apoptosis in dopamine neurons of the substantia nigra, but are not required for axon degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2009.124

Role of Dickkopf-1, an antagonist of the Wnt/beta-catenin signaling pathway, in estrogen-induced neuroprotection and attenuation of tau phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2009.124

Docking interactions in the c-Jun N-terminal kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2009.124

The JNK-interacting protein-1 scaffold protein targets MAPK phosphatase-7 to dephosphorylate JNK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2009.124

p63 is an essential proapoptotic protein during neural development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2009.124

Siah1 interacts with the scaffold protein POSH to promote JNK activation and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2009.124

Caspase-8- and JNK-dependent AP-1 activation is required for Fas ligand-induced IL-8 production

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2009.124

Neuroprotection against ischaemic brain injury by a GluR6-9c peptide containing the TAT protein transduction sequence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2009.124

Exogenous nitric oxide negatively regulates c-Jun N-terminal kinase activation via inhibiting endogenous NO-induced S-nitrosylation during cerebral ischemia and reperfusion in rat hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2009.124

The Isopeptidase Inhibitor G5 Triggers a Caspase-independent Necrotic Death in Cells Resistant to Apoptosis: A COMPARATIVE STUDY WITH THE PROTEASOME INHIBITOR BORTEZOMIB

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2009.124

Neuroprotection of Tat-GluR6-9c against neuronal death induced by kainate in rat hippocampus via nuclear and non-nuclear pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2009.124

Bcl-2 homodimerization involves two distinct binding surfaces, a topographic arrangement that provides an effective mechanism for Bcl-2 to capture activated Bax

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2009.124

Effects of systemic administration of ciliary neurotrophic factor on Bax and Bcl-2 proteins in the lumbar spinal cord of neonatal rats after sciatic nerve transection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2009.124

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2009.124

Caspase-2 triggers Bax-Bak-dependent and -independent cell death in colon cancer cells treated with resveratrol.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2009.124

Pro-apoptotic Bim Induction in Response to Nerve Growth Factor Deprivation Requires Simultaneous Activation of Three Different Death Signaling Pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2009.124

Neuropathology of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2009.124

7 January 2021

inferred from DOI database lookup

Inhibition of JNK by overexpression of the JNL binding domain of JIP-1 prevents apoptosis in sympathetic neurons

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2009.124

7 January 2021

inferred from DOI database lookup

K252a prevents nigral dopaminergic cell death induced by 6-hydroxydopamine through inhibition of both mixed-lineage kinase 3/c-Jun NH2-terminal kinase 3 (JNK3) and apoptosis-inducing kinase 1/JNK3 signaling pathways

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2009.124

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/LABINVEST.2009.124

1 reference

Dimensions Publication ID

16 November 2017

1002597800

0 references

Fatcat ID

release_fuxgupyosjgsnp677zv4i6mhca

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/fuxgupyosjgsnp677zv4i6mhca

24 November 2022

mapped directly with Wikidata item

1 reference