(Q43241664)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21446022%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

title

Mitochondrial DNA deletions and neurodegeneration in multiple sclerosis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21446022%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

0 references

0 references

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21446022%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Graham R Campbell

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21446022%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Owain W. Howell

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21446022%20AND%20SRC:MED&resulttype=core&format=json

Douglass Matthew Turnbull

26 January 2020

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21446022%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

5

Richard Reynolds

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21446022%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

author name string

Iryna Ziabreva

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21446022%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Amy K Reeve

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21446022%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Kim J Krishnan

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21446022%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Don J Mahad

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21446022%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

publication date

8 November 2010

1 reference

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26 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21446022%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

volume

69

1 reference

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26 January 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21446022%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

page(s)

481-492

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21446022%20AND%20SRC:MED&resulttype=core&format=json

Mitochondrial DNA mutations affect calcium handling in differentiated neurons

26 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580047

On the timing and the extent of clonal expansion of mtDNA deletions: evidence from single-molecule PCR.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580047

Mitochondrial changes within axons in multiple sclerosis

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580047

Mitochondrial DNA mutations in disease, aging, and neurodegeneration

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580047

The inhibition of mitochondrial cytochrome oxidase by the gases carbon monoxide, nitric oxide, hydrogen cyanide and hydrogen sulfide: chemical mechanism and physiological significance

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580047

Neurogenesis in the chronic lesions of multiple sclerosis

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580047

Gray matter atrophy in multiple sclerosis: a longitudinal study

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580047

Mitochondrial DNA repair in aging and disease

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580047

What causes mitochondrial DNA deletions in human cells?

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580047

Lack of mitochondrial DNA deletions in lesions of multiple sclerosis

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580047

The ageing mitochondrial genome

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580047

Pathogenesis of axonal and neuronal damage in multiple sclerosis

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580047

The involvement of mitochondria in the pathogenesis of multiple sclerosis.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580047

Optical imaging techniques (histochemical, immunohistochemical, and in situ hybridization staining methods) to visualize mitochondria

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580047

Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580047

The neurobiology of multiple sclerosis: genes, inflammation, and neurodegeneration

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580047

Mitochondrial DNA-deletion mutations accumulate intracellularly to detrimental levels in aged human skeletal muscle fibers

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580047

High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580047

NMDA receptors mediate calcium accumulation in myelin during chemical ischaemia

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580047

Mitochondrial DNA mutations in human disease

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580047

25 May 2018

Mitochondrial disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580047

Neuropathological aspects of mitochondrial DNA disease

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580047

Oxidative DNA damage: mechanisms, mutation, and disease

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580047

Mitochondrial respiratory-chain diseases

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580047

Mitochondrial biogenesis in mammals: the role of endogenous nitric oxide.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580047

Mitochondria, Ca2+ and neurodegenerative disease

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580047

Detection and quantification of mitochondrial DNA deletions in individual cells by real-time PCR.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580047

Frequent intracellular clonal expansions of somatic mtDNA mutations: significance and mechanisms

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580047

Endotoxin-stimulated nitric oxide production inhibits expression of cytochrome c oxidase in ANA-1 murine macrophages

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580047

Random intracellular drift explains the clonal expansion of mitochondrial DNA mutations with age.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580047

Excitotoxicity and mitochondria

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580047

Enhanced number and activity of mitochondria in multiple sclerosis lesions

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580047

Impaired regulation of electron transport chain subunit genes by nuclear respiratory factor 2 in multiple sclerosis

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580047

Dopaminergic midbrain neurons are the prime target for mitochondrial DNA deletions

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580047

Nature of mitochondrial DNA deletions in substantia nigra neurons

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580047

Mitochondrial DNA deletions are abundant and cause functional impairment in aged human substantia nigra neurons.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580047

Mitochondrial dysfunction as a cause of axonal degeneration in multiple sclerosis patients.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580047

Subpial demyelination in the cerebral cortex of multiple sclerosis patients.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580047

Transected neurites, apoptotic neurons, and reduced inflammation in cortical multiple sclerosis lesions.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3580047

Aspects, mechanism, and biological relevance of mitochondrial protein nitration sustained by mitochondrial nitric oxide synthase

15 August 2018

1 reference

12 December 2020

The natural history of multiple sclerosis: a geographically based study. 2. Predictive value of the early clinical course

1 reference

12 December 2020

Mitochondrial DNA deletions in muscle fibers in inclusion body myositis

1 reference

12 December 2020

Multiple mitochondrial DNA deletions in sporadic inclusion body myositis: a study of 56 patients

1 reference

12 December 2020

A multiplex real-time PCR method to detect and quantify mitochondrial DNA deletions in individual cells

1 reference

12 December 2020

Gray matter atrophy is related to long-term disability in multiple sclerosis

1 reference

12 December 2020

Oxidative damage to mitochondrial DNA and activity of mitochondrial enzymes in chronic active lesions of multiple sclerosis

1 reference

12 December 2020

Identifiers

DOI

10.1002/ANA.22109

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21446022%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21446022%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

1 reference