(Q43279324)

18 November 2017

Structural model for the binding sites of allosterically potentiating ligands on nicotinic acetylcholine receptors (English)

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18 November 2017

1

Edgar Luttmann

0 references

Gregor Fels

6

object named as

Gregor Fels

1 reference

18 November 2017

Edgar Luttmann

1

1 reference

18 November 2017

Jürgen Ludwig

2

1 reference

18 November 2017

Anja Höffle-Maas

3

1 reference

18 November 2017

Marek Samochocki

4

1 reference

18 November 2017

Alfred Maelicke

5

1 reference

18 November 2017

1 November 2009

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18 November 2017

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18 November 2017

4

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18 November 2017

11

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18 November 2017

1874-1882

1 reference

The Chemistry Development Kit (CDK): an open-source Java library for Chemo- and Bioinformatics

18 November 2017

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900320

Amyloid plaque core protein in Alzheimer disease and Down syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900320

7 January 2021

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900320

7 January 2021

A quantitative morphometric analysis of the neuronal and synaptic content of the frontal and temporal cortex in patients with Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900320

7 January 2021

Alzheimer's disease is a synaptic failure

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900320

7 January 2021

Physical basis of cognitive alterations in alzheimer's disease: Synapse loss is the major correlate of cognitive impairment

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900320

7 January 2021

The pharmacology of galanthamine and its analogues

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900320

7 January 2021

A 52-week study of the efficacy of rivastigmine in patients with mild to moderately severe Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900320

7 January 2021

Long-term efficacy and safety of donepezil in the treatment of Alzheimer's disease: an interim analysis of the results of a US multicentre open label extension study

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900320

7 January 2021

Cholinergic function and Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900320

7 January 2021

Cholinesterases: new roles in brain function and in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900320

7 January 2021

Allosterically potentiating ligands of nicotinic receptors as a treatment strategy for Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900320

7 January 2021

The nicotinic allosteric potentiating ligand galantamine facilitates synaptic transmission in the mammalian central nervous system

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900320

7 January 2021

Allosteric modulation of nicotinic acetylcholine receptors as a treatment strategy for Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900320

7 January 2021

Galantamine is an allosterically potentiating ligand of neuronal nicotinic but not of muscarinic acetylcholine receptors

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900320

7 January 2021

Effect of galantamine on the human alpha7 neuronal nicotinic acetylcholine receptor, the Torpedo nicotinic acetylcholine receptor and spontaneous cholinergic synaptic activity

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900320

7 January 2021

Physostigmine, galanthamine and codeine act as 'noncompetitive nicotinic receptor agonists' on clonal rat pheochromocytoma cells

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900320

7 January 2021

Desensitization is a property of the cholinergic binding region of the nicotinic acetylcholine receptor, not of the receptor-integral ion channel

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900320

7 January 2021

Photoaffinity labeling of Torpedo acetylcholine receptor by physostigmine

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900320

7 January 2021

Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900320

7 January 2021

Galanthamine and Non-competitive Inhibitor Binding to ACh-binding Protein: Evidence for a Binding Site on Non-α-subunit Interfaces of Heteromeric Neuronal Nicotinic Receptors

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900320

7 January 2021

Crystal structure of a Cbtx-AChBP complex reveals essential interactions between snake alpha-neurotoxins and nicotinic receptors.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900320

7 January 2021

Crystal structure of nicotinic acetylcholine receptor homolog AChBP in complex with an alpha-conotoxin PnIA variant.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900320

7 January 2021

Nicotine and carbamylcholine binding to nicotinic acetylcholine receptors as studied in AChBP crystal structures

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900320

7 January 2021

Crystal structure of the extracellular domain of nAChR alpha1 bound to alpha-bungarotoxin at 1.94 A resolution

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900320

7 January 2021

Structures of Aplysia AChBP complexes with nicotinic agonists and antagonists reveal distinctive binding interfaces and conformations

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900320

7 January 2021

X-ray structure of a prokaryotic pentameric ligand-gated ion channel

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900320

7 January 2021

A glia-derived acetylcholine-binding protein that modulates synaptic transmission.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900320

7 January 2021

Nicotinic acetylcholine receptor at 9 A resolution.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900320

7 January 2021

Nicotinic acetylcholine receptor at 4.6 A resolution: transverse tunnels in the channel wall.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900320

7 January 2021

Refined structure of the nicotinic acetylcholine receptor at 4A resolution

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900320

7 January 2021

Structure and gating mechanism of the acetylcholine receptor pore

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900320

7 January 2021

Models of the extracellular domain of the nicotinic receptors and of agonist- and Ca2+-binding sites

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900320

7 January 2021

A structural model of agonist binding to the α3β4 neuronal nicotinic receptor

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900320

7 January 2021

Acetylcholine nicotinic receptors: finding the putative binding site of allosteric modulators using the "blind docking" approach

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900320

7 January 2021

Rational understanding of nicotinic receptors drug binding

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900320

7 January 2021

Ligand-induced conformational change in the alpha7 nicotinic receptor ligand binding domain

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900320

7 January 2021

A gating mechanism proposed from a simulation of a human alpha7 nicotinic acetylcholine receptor

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900320

7 January 2021

Conformational dynamics of the nicotinic acetylcholine receptor channel: a 35-ns molecular dynamics simulation study

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900320

7 January 2021

Structural model of nicotinic acetylcholine receptor isotypes bound to acetylcholine and nicotine

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900320

7 January 2021

The nicotinic receptor ligand binding domain

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900320

7 January 2021

Modeling differential binding of alpha4beta2 nicotinic acetylcholine receptor with agonists and antagonists.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900320

7 January 2021

Combined roles of loops C and D in the interactions of a neonicotinoid insecticide imidacloprid with the alpha4beta2 nicotinic acetylcholine receptor

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900320

7 January 2021

Localization of agonist and competitive antagonist binding sites on nicotinic acetylcholine receptors

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900320

7 January 2021

Galantamine is an allosterically potentiating ligand of the human alpha4/beta2 nAChR

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900320

7 January 2021

Automated docking using a Lamarckian genetic algorithm and an empirical binding free energy function

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900320

7 January 2021

Initial coupling of binding to gating mediated by conserved residues in the muscle nicotinic receptor

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900320

7 January 2021

Mutations of a conserved lysine residue in the N-terminal domain of alpha7 nicotinic receptors affect gating and binding of nicotinic agonists

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900320

7 January 2021

Galantamine activates muscle-type nicotinic acetylcholine receptors without binding to the acetylcholine-binding site.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900320

7 January 2021

Cholinergic drugs potentiate human nicotinic alpha4beta2 acetylcholine receptors by a competitive mechanism

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900320

7 January 2021

Recent advances in Cys-loop receptor structure and function

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900320

7 January 2021

Dynamic structural investigations on the torpedo nicotinic acetylcholine receptor by time-resolved photoaffinity labeling

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900320

7 January 2021

The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900320

7 January 2021

TEXshade: shading and labeling of multiple sequence alignments using LATEX2 epsilon.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900320

7 January 2021

SWISS-MODEL: An automated protein homology-modeling server

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900320

7 January 2021

Evaluation of the FLEXX incremental construction algorithm for protein-ligand docking

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900320

7 January 2021

Identifiers

DOI

10.1002/CMDC.200900320

1 reference

18 November 2017

1 reference